(a)
Interpretation: The given compounds has to be prepared from methyl phenyl
Concept introduction: A crossed-claisen condensation is also a condensation reaction between a ketone and an ester. Primarily one product will form from crossed-claisen condensation when one of the ketone or easter do not have any alpha hydrogens.
If both ester and ketone have alpha hydrogens then primarily one product can form if LDA is used to remove alpha hydrogen to form the enolate ion. The other compound is added slowly to the enolate ion.
(b)
Interpretation: The given compounds has to be prepared from methyl phenyl ketone.
Concept introduction: A crossed-claisen condensation is also a condensation reaction between a ketone and an ester. Primarily one product will form from crossed-claisen condensation when one of the ketone or easter do not have any alpha hydrogens.
If both ester and ketone have alpha hydrogens then primarily one product can form if LDA is used to remove alpha hydrogen to form the enolate ion. The other compound is added slowly to the enolate ion.
(c)
Interpretation: The given compounds has to be prepared from methyl phenyl ketone.
Concept introduction: A crossed-claisen condensation is also a condensation reaction between a ketone and an ester. Primarily one product will form from crossed-claisen condensation when one of the ketone or easter do not have any alpha hydrogens.
If both ester and ketone have alpha hydrogens then primarily one product can form if LDA is used to remove alpha hydrogen to form the enolate ion. The other compound is added slowly to the enolate ion.
Want to see the full answer?
Check out a sample textbook solutionChapter 18 Solutions
Organic Chemistry
- Identify all carbonyl compounds that can undergo nucleophilic addition reactions from the following:arrow_forwardHow can the following compounds be prepared from a carbonyl compound that has one less carbon than the desired product?arrow_forwardWhat ketones are prepared by the following reactions?arrow_forward
- What products are formed by acidic hydrolysis of the following compound? benzaldehyde and butan-1-d benzeie acid and butan-2-d 2-methylbutanoic acid and phenol benzoic acid and methyl ethyl ketonearrow_forwardShow how the benzaldehyde can be prepared from benzene:arrow_forwardWhat is the product of the following ketone reduction reaction? O cyclohexanol cyclohexanone cyclohexane O cyclohexanal + H₂ Niarrow_forward