Concept explainers
(a)
Interpretation:
The phosphate of ATP that undergoes the nucleophilic hydroxy group of ribose-5-phosphate is to be identified and the by-product of the reaction is to be given.
Concept Introduction:
PRPP is an important intermediate in the biosynthesis of
(b)
Interpretation:
The reaction of ammonia with PRPP with correct stereochemistry, is to be determined.
Concept introduction:
The lone pairs on nitrogen in ammonia will attack on the carbon atom resulting in the formation of a new carbon-nitrogen bond. Simultaneously, the bond between carbon and the oxygen atom in pyrophosphate breaks.
(c)
Interpretation:
The other biochemical reaction which ensures that the reaction of ammonia with PRPP goes to completion is to be determined.
Concept introduction:
The irreversible last step in the reaction sequence drives the reaction to completion.
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Organic Chemistry
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- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning