Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 2, Problem 20RQ
Summary Introduction
To review:
Definition of the following terminologies:
(a) Ciliopathy
(b) Retinitis pigmentosum
(c) Polycystic kidney disease
(d) Bardet-Biedl syndrome
(e) Anterograde transport
Introduction:
When there are abnormalities present in the genome, it results in a genetic disorder. It has been observed that most genetic disorders are rare as, generally, only one person gets affected from it among thousands or millions of people.
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Question 1.
Enzymes, proteins and deoxyribonucleic acid (DNA) are important biological
macromolecules. Enzymes are not only speed up the reaction, but also are necessary for DNA
reproduction.
c) Describe an example of biomedical application that utilizes a protein folding technique.
d) Describe the effect of pH on the oxygen binding affinity of hemoglobin.
Question 11
B.1.351 is a variant of SARS-CoV-2. It has the amino acid substitution N501Y in the spike protein
on the virus surface. In cellular fluids at -pH 7 the wild type spike protein has a net negative
charge. This substitution will make the spike protein
O more negative
O less hydrophobic
O less negative
O absorb more UV light
Please provide explanation, thank you!
There are two types of prokaryotes: bacteria and____________________.
Chapter 2 Solutions
Biochemistry: The Molecular Basis of Life
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