(a)
Interpretation:
The curved-arrow mechanism for the given reaction is to be stated. The role of weak acid ammonium chloride is also to be stated.
Concept introduction:
The nitrogen groups are not good leaving groups in the form of negatively charged nitrogen because of stronger basic nature. Even if the ring strain is removed still that is not enough for nitrogen to leave as negative ion. Therefore, acid is used to protonate nitrogen before its elimination so that it will leave as neutral nitrogen.
(b)
Interpretation:
An explanation as to why the reaction of aziridine requires a weak acid is to be stated.
Concept introduction:
The nitrogen groups are not good leaving groups in the form of negatively charged nitrogen because of stronger basic nature. Even if the ring strain is removed still that is not enough for nitrogen to leave as negative ion. Therefore, acid is used to protonate nitrogen before its elimination so that it will leave as neutral nitrogen.
(b)
Interpretation:
The suggestion of using a dilute solution of strong acid
Concept introduction:
The nitrogen groups are not good leaving groups in the form of negatively charged nitrogen because of stronger basic nature. Even if the ring strain is removed still that is not enough for nitrogen to leave as negative ion. Therefore, acid is used to protonate nitrogen before its elimination so that it will leave as neutral nitrogen.
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Organic Chemistry
- Which is the stronger acid in each of the following pairs? Explain your reasoning. (a) Phenol or p-hydroxybenzaldehyde (b) m-Cyanophenol or p-cyanophenol (c) o-Fluorophenol or p-fluorophenolarrow_forward(a) Account for the following :(i) Propanal is more reactive than propanone towards nucleophilic reagents.(ii) Electrophilic substitution in benzoic acid takes place at meta position.(iii) Carboxylic acids do not give characteristic reactions of carbonyl group.(b) Give simple chemical test to distinguish between the following pairs of compounds:(i) Acetophenone and benzaldehyde(ii) Benzoic acid and ethylbenzoate.arrow_forward(b) Suggest a reasonable biosynthesis for the naturally occurring alkaloid coniine (isolated from hemlock), starting from octanoic acid. Coniinearrow_forward
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- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning