General Physics, 2nd Edition
General Physics, 2nd Edition
2nd Edition
ISBN: 9780471522782
Author: Morton M. Sternheim
Publisher: WILEY
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Chapter 18, Problem 4RQ
To determine

In the resting state of an axon. there are far more _ions on the outside of the membrane than inside and far more __ ions on the inside than outside.

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12. (a) Using Eq. AQ=CAV and the data in the Table, calculate the number of ions entering the axon during the action potential, per meter of nonmyelinated axon length. (The charge on the ion is 1.6 x 10-19 coulomb.) (b) During the resting state of the axon, typical concentrations of sodium and potassium ions inside the axon are 15 and 150 millimole/liter, respectively. From the data in the Table, calculate the number of ions per meter length of the axon. Table 13.1 Properties of Sample Axons Hint: 1 F (farad) = 1coulomb/1 volt Property Nonmyelinated axon Myelinated axon Axon radius 5 x 10-m 5 x 10-6 m 1 mole /liter = 6.02 x 1020 particles (ions, atoms, etc. ) Resistance per unit length of fluid cm 6.37 x 10°2/m 6.37 x 10°2/m both inside and outside axon (r) Conductivity per unit length of axon membrane (gm) 1.25 x 10-4 mho/m In the resting state, the axon voltage is -70mV. During the pulse, the voltage changes to about +30mV, resulting in a net voltage change across the membrane of 100…
a) How does voltage change over distance from the stimulator on the artificial axon? AND why does this occur? (Think: where is the current going?)         b) How and why are neurons affected by the addition of myelin (think membrane resistance, capacitance, and the length constant)?
The velocity of spike propagation is proportional to the following combination of factors: 1 a C, V R„R, m Where a is the radius of the axon, Rm and R; are specific resistances of the membrane and the internal buffer, respectively. If we double the radius and simultaneously increase the concentration of salt inside the axon twice (i.e. R; decreases two times), by how many fold will the velocity change?
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