Study Guide for Campbell Biology
11th Edition
ISBN: 9780134443775
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece, Martha R. Taylor, Michael A. Pollock
Publisher: PEARSON
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Textbook Question
Chapter 9, Problem 22TYK
Brown fat, which is found in newborn infants and hibernating mammals, has uncoupler proteins that, when activated, make the inner mitochondrial membrane leaky to H+. What is the function of brown fat?
- a. It produces more ATP than does regular fat and is also found in the flight muscles of ducks and geese, providing more energy for long-distance migrations.
- b. It lowers the pH of the intermembrane space, which results in the production of more ATP per gram than is produced by the oxidation of glucose or regular fat tissue.
- c. Because it dissipates the proton gradient, it generates heat through
cellular respiration without producing ATP, thereby raising the body temperature of hibernating mammals or newborn infants. - d. Its main function is insulation in the endothermic animals in which is it common.
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When the chemical dinitrophenol (DNP) is added to mitochondria, the inner membrane becomes permeable to protons. When the drug valinomycin is added to mitochondria, the inner membrane becomes permeable to potassium ions (K+).
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The fatty acid side chains of the phospholipids in the inner mitochondrial membrane exhibit a large proportion of multiple unsaturations. As a result, will the membrane be hydrophobic or hydrophilic? Also will it be more fluid or more rigid? How do these characteristics help explain the observation that the inner membrane is impermeable to ions such as Mg2+ and Cl–? Hint: what moves these ions through the membrane?
What would be the effect on ATP production of decreasing the pH inside the mitochondrial matrix? Explain
Chapter 9 Solutions
Study Guide for Campbell Biology
Ch. 9 - Fill in the following summary equation for...Ch. 9 - Fill in the appropriate terms in the following...Ch. 9 - a. In the conversion of glucose and O2 to CO2 and...Ch. 9 - a. NAD+ is called a(n) ____________________. b....Ch. 9 - Fill in the three stages of cellular respiration...Ch. 9 - Fill in the blanks in the following summary...Ch. 9 - Fill in the blanks in the following diagram of the...Ch. 9 - Label the following diagram of oxidative...Ch. 9 - Fill in the following tally for the maximum ATP...Ch. 9 - How much more ATP can be generated by aerobic...
Ch. 9 - This chapter describes how catabolic pathways...Ch. 9 - Prob. 2SYKCh. 9 - Fill in the following table to summarize...Ch. 9 - When electrons move closer to a more...Ch. 9 - In the reaction C6H12O6 + 6 O2 6 CO2 + 6 H2O, a....Ch. 9 - In which of the following conversions is the first...Ch. 9 - Some prokaryotes use anaerobic respiration, a...Ch. 9 - Which of the following reactions is incorrectly...Ch. 9 - In which organelle of a plant cell does the citric...Ch. 9 - Which of the following compounds produces the most...Ch. 9 - Aerobic eukaryotes produce CO2 as a by-product...Ch. 9 - Which of the following statements correctly...Ch. 9 - In the electron transport system, H+ ions are...Ch. 9 - When glucose is oxidized to CO2 and water,...Ch. 9 - The energy required for the chemiosmotic synthesis...Ch. 9 - Which of the following statements correctly...Ch. 9 - The citric acid cycle is best described as a. the...Ch. 9 - Fermentation produces less ATP than cellular...Ch. 9 - If muscle cells do not receive enough oxygen from...Ch. 9 - Glucose made from six radioactively labeled carbon...Ch. 9 - Glycolysis is considered one of the first...Ch. 9 - Which of the following substances produces the...Ch. 9 - Fats and proteins can be used as fuel in the cell...Ch. 9 - Which of the following statements is false...Ch. 9 - Brown fat, which is found in newborn infants and...
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- Under conditions where cellular ATP levels are high the rate of electron transport in mitochondria slows down. This is referred to as “respiratory control” What is the mechanism behind respiratory control? A. A high pH gradient slows proton pumping, which in turn slows electron transport. B. Glucose binds to the ATP synthase complex slowing the rate of diffusion of protons across the membrane. C. Molecules of UQ within the membrane change shape, which slows their rate of diffusion. D. ATP binds to NADH dehydrogenase complex (Complex 1) slowing the rate of NADH oxidation.arrow_forwardAlthough the outer mitochondrial membrane is permeable to all small molecules, the inner mitochondrial membrane is essentially impermeable in the absence of specific transport proteins. Consider this information answer: The ATP generated by oxidative respiration is used throughout the cell. The majority of ATP production occurs in the mitochondrial matrix. How do you think ATP is made accessible to enzymes in the cytosol and other organelles?arrow_forwardPredict the outcome of a mitochondrial membrane that is more permeable to hydrogen ions than normal. answer choices A.) Increased levels of inorganic phosphate in the mitochondrial matrix B.) Reduced formation of water C.) Reduced activity of electron transport chain D.) Increased activity of ATP synthasearrow_forward
- In the 1930s, some physicians prescribed low doses of a compound called dinitrophenol (DNP) to help patients lose weight. This unsafe method was abandoned after some patients died. DNP uncouples the chemiosmotic machinery by making the lipid bilayer of the inner mitochondrial membrane leaky to H+. Chemical agents that cause this effect are called uncouplers. Explain how this could cause weight loss and also death. Considering the danger, is there any use for compounds like DNP or other uncouplers?arrow_forwardThe mitochondrial membrane potential is an indicator of cell viability. Think about mitochondrial function and decide which of these statements best describes the mitochondrial membrane potential. a.) A voltage that reflects the movement of ATP across the outer mitochondrial membrane b.) A voltage that reflects the movement of protons across the outer mitochondrial membrane c.) A voltage that reflects the movement of protons across the inner mitochondrial membrane d.) A voltage that reflects the movement of ATP across the inner mitochondrial membranearrow_forwardIn the 1930s, some physicians prescribed low doses of a compound called dinitrophenol (DNP) to help patients lose weight. This unsafe method was abandoned after some patients died. DNP uncouples the chemiosmotic machinery by making the lipid bilayer of the inner mitochondrial membrane leaky to H+ . Explain how this could cause weight loss and death.arrow_forward
- Uncoupling agents are proteins spanning the inner mitochondrial membrane that allow protons to pass through the membrane and bypass the channel of ATP synthase. Describe the consequences to the proton gradient and ATP production.?arrow_forwardIt has been noted that the mitochondria of muscle cells often have more cristae than the mitochondria of liver cells. Provide an explanation for this observation.arrow_forwardAlthough the outer mitochondrial membrane is permeable to all small molecules, the inner mitochondrial membrane is essentially impermeable in the absence of specific transport proteins. Consider this information answer: If the inner mitochondrial membrane were rendered as permeable as the outer membrane, how would that affect oxidative phosphorylation? Which specific processes would stop and which remain?arrow_forward
- A principle of biology is that structure determines function.Explain how the invaginations of the inner mitochondrialmembrane are related to mitochondrial function.arrow_forwardDuring cellular respiration, 60 molecules of CO2 were given off as waste. a. How many pyruvate molecules were produced in glycolysis? b. The total amount of ATP produced by complete cellular respiration would be? c. The amount of energy available (Net ATP) to cell as ATP would be?arrow_forwardWhich of the takes place during oxidative phosphorylation in mitochondria? a. protons are pumped from the matrix to the intermembrane space b. protons are pumped from the intermembrane space to the matrix c. electrons are pumped from the matrix to the intermembrane space d. electrons are pumped from the intermembrane space to the matrix e. NADH is pumped from the matrix to the intermembrane spacearrow_forward
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