Order the cofactors based on their use in the mechanism of the a-etogluterate dehydrogenase complex. 1. Stabilizes a carbanion due to decarboxylation 2. Allows for the splitting of the carbon skeleton from the electron pair generated in a redox reaction 3. Enzyme bond electron carrier that is part of dihydrolipoyl dehydrogenase 4. Final electron acceptor in the overall reaction catalyzed by this complex

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter18: Glycolysis
Section: Chapter Questions
Problem 24P: Based on your knowledge of the structure of NAD+ and an assumption that coenzyme dissociation is the...
icon
Related questions
Question

Order the cofactors based on their use in the mechanism of the a-etogluterate dehydrogenase complex.

1. Stabilizes a carbanion due to decarboxylation

2. Allows for the splitting of the carbon skeleton from the electron pair generated in a redox reaction

3. Enzyme bond electron carrier that is part of dihydrolipoyl dehydrogenase

4. Final electron acceptor in the overall reaction catalyzed by this complex

1

2

3

4

answer choices: lipoamide, biotin, 2 Fe - 2S cluster, TPP, NAD+, FAD

Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 6 steps with 6 images

Blurred answer
Knowledge Booster
Metabolic diseases
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning