Biology: Life on Earth with Physiology (11th Edition)
11th Edition
ISBN: 9780133923001
Author: Gerald Audesirk, Teresa Audesirk, Bruce E. Byers
Publisher: PEARSON
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Textbook Question
Chapter 9.6, Problem 1TC
What would happen if a cell suffered a mutation that turned a growth factor receptor “on” all the time so that it activated the intracellular cascade even without growth factors present?
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Many malignant tumors are characterized by the activation of one or more growth-factor receptors. What is the catalytic activity associated with transmembrane growth factor receptors such as the EGF receptor?
RAS is a signal transducer that acts as a switch for turning on cell division. Drag the descriptions below to their proper places on the
figure to show the sequence of events.
When growth factor
binds to the receptor,
the intracellular domain
activates RAS by
facilitating exchange of
GDP for GTP.
When no growth factor
is bound to the
extracellular receptor,
RAS is bound to GDP
and is inactive.
RAS activates the
first of three
sequential kinase
proteins termed the
MAP kinase cascade.
Cell proliferation
proceeds as the
machinery for cell
division is set in
motion.
The end result of the
MAP kinase cascade
is activation of a
transcription factor.
Receptor
1
Ras
GDP
2
4
5
Growth factor
Ras
GTP
What is the main benefit of cell signaling over long distances (ex: signaling via hormone secretion into the bloodstream)?
Chapter 9 Solutions
Biology: Life on Earth with Physiology (11th Edition)
Ch. 9.1 - describe the types of cells found in a...Ch. 9.1 - describe the functions of cell division in...Ch. 9.2 - describe the prokaryotic cell cycle and the major...Ch. 9.3 - describe the structure of a eukaryotic chromosome?Ch. 9.3 - describe the functions of telomeres and...Ch. 9.4 - Body, Heal Thyself Ligaments and tendons have a...Ch. 9.4 - describe the events of the eukaryotic cell cycle?Ch. 9.4 - explain the difference between mitotic cell...Ch. 9.5 - Body, Heal Thyself The precision of mitotic cell...Ch. 9.5 - describe the steps of mitotic cell division?
Ch. 9.5 - What would the consequences be if one set of...Ch. 9.5 - describe the usual outcome of mitotic cell...Ch. 9.5 - Prob. 3CYLCh. 9.6 - Body, Heal Thyself Bartolo Colns physicians wanted...Ch. 9.6 - Prob. 1CTCh. 9.6 - describe the interactions among growth factors,...Ch. 9.6 - Yesterday, when Daniel was showering after a...Ch. 9.6 - The saliva of dogs, like the saliva of most...Ch. 9.6 - What would happen if a cell suffered a mutation...Ch. 9.6 - explain how a cell protects against producing...Ch. 9 - Most nerve cells in the adult human central...Ch. 9 - The genetic material of all living organisms is...Ch. 9 - A cell that remains capable of dividing throughout...Ch. 9 - Diagram and describe the eukaryotic cell cycle....Ch. 9 - Prob. 2ACCh. 9 - Prokaryotic cells divide by a process called...Ch. 9 - Prob. 2MCCh. 9 - Prob. 2RQCh. 9 - Prob. 3FIBCh. 9 - Prob. 3MCCh. 9 - Prob. 3RQCh. 9 - Prob. 4FIBCh. 9 - How does prokaryotic fission differ from...Ch. 9 - Define the following terms: centromere, telomere,...Ch. 9 - The four phases of mitosis are _________,...Ch. 9 - Prob. 5MCCh. 9 - Prob. 5RQCh. 9 - Prob. 6FIBCh. 9 - Prob. 6RQCh. 9 - Prob. 7RQ
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