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Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
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Textbook Question
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Chapter 5, Problem 10P
A study was conducted assessing the effect of observer training on measurement of blood pressure based on NHANES data from 1999–2000 (Ostchega, et al., [1]). A goal was that the difference in recorded blood pressure between the observer and trainer be ≤ 2 mm Hg in absolute value. It was reported that the
If we assume that the distribution of Δ is
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A study was conducted assessing the effect of observer training on measurement of blood pressure based on NHANES data from 1999–2000 (Ostchega, et al., [1]). A goal was that the difference in recorded blood pressure between the observer and trainer be ≤ 2 mm Hg in absolute value. It was reported that the mean difference in systolic blood pressure (SBP) between observers and trainers (i.e., mean observer SBP minus trainer SBP) = mean (Δ) was 0.189 mm Hg with sd = 2.428 mm Hg.
1. If we assume that the distribution of Δ is normally distributed, then what % of (observer, trainer) pairs have a mean difference of ≥ 2 mm Hg in absolute value (i.e., either ≥ 2 mm Hg or ≤ −2 mm Hg)?
2. If we assume that the distribution of Δ is normally distributed, then what is the 90 percentile (i.e., the upper decile) and 10 percentile (i.e., the lower decile) of the distribution?
Albumin is a liver protein that helps circulate vitamins throughout the body. Reduced Albumin
has been associated with severe illness with Covid-19 patients. Suppose we wanted to conduct
a study to compare the mean Albumin concentration (g/L) between a sample of adult patients
hospitalized for Covid 19 (Sample Mean= 32.8, s=6.0) to the mean albumin concentration (g/L)
of healthy adults (u=34.1, o=7.13). How many patients would need to enroll from the hospital to
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A. 267
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Peak expiratory flow (PEF) is a measure of a patient’s ability to expel air from the lungs. Patients with asthma or other respiratory conditions often have restricted PEF. The mean PEF for children free of asthma is 306. An investigator conducts a study to investigate whether there is a difference in mean PEF in children with chronic bronchitis as compared to those without asthma or other respiratory conditions that often have restricted PEF. Data on PEF are collected and summarized below. Based on the data, is there statistical evidence of a lower mean PEF in children with chronic bronchitis as compared to those without? Run the appropriate test at a = 0.05.
Group
Number of Children
Mean PEF
Std Dev PEF
Chronic Bronchitis
25
274
59
No Chronic Bronchitis
25
317
73
Chapter 5 Solutions
Fundamentals of Biostatistics
Ch. 5.4 - What is the difference between a...Ch. 5.4 - Suppose a continuous random variable can only take...Ch. 5.4 - What is a standard normal distribution?Ch. 5.4 - (a) What is the area to the left of 0.2 under a...Ch. 5.4 - (a) What is z.30? What does it mean? (b) What is...Ch. 5.5 - What is the difference between a standard normal...Ch. 5.5 - What does the principle of standardization mean?Ch. 5.5 - Suppose the distribution of serum-cholesterol...Ch. 5.8 - Why do we use the normal approximation to the...Ch. 5.8 - Prob. C.2RE
Ch. 5.8 - The prevalence of glaucoma among the elderly in...Ch. 5.8 - The number of deaths from heart failure in a...Ch. 5 - Because serum cholesterol is related to age and...Ch. 5 - Because serum cholesterol is related to age and...Ch. 5 - Because serum cholesterol is related to age and...Ch. 5 - Because serum cholesterol is related to age and...Ch. 5 - Because serum cholesterol is related to age and...Ch. 5 - Suppose that total carbohydrate intake in 12- to...Ch. 5 - Suppose that total carbohydrate intake in 12- to...Ch. 5 - Suppose boys in this age range who live below the...Ch. 5 - Suppose boys in this age range who live below the...Ch. 5 - A study was conducted assessing the effect of...Ch. 5 - A study was conducted assessing the effect of...Ch. 5 - The duration of cigarette smoking has been linked...Ch. 5 - The duration of cigarette smoking has been linked...Ch. 5 - Serum cholesterol is an important risk factor for...Ch. 5 - Serum cholesterol is an important risk factor for...Ch. 5 - Serum cholesterol is an important risk factor for...Ch. 5 - People are classified as hypertensive if their...Ch. 5 - People are classified as hypertensive if their...Ch. 5 - People are classified as hypertensive if their...Ch. 5 - People are classified as hypertensive if their...Ch. 5 - Forced expiratory volume (FEV) is an index of...Ch. 5 - Forced expiratory volume (FEV) is an index of...Ch. 5 - Forced expiratory volume (FEV) is an index of...Ch. 5 - Forced expiratory volume (FEV) is an index of...Ch. 5 - The differential is a standard measurement made...Ch. 5 - The differential is a standard measurement made...Ch. 5 - The differential is a standard measurement made...Ch. 5 - The differential is a standard measurement made...Ch. 5 - The differential is a standard measurement made...Ch. 5 - The differential is a standard measurement made...Ch. 5 - Blood Chemistry In pharmacologic research a...Ch. 5 - Blood Chemistry In pharmacologic research a...Ch. 5 - Blood Chemistry In pharmacologic research a...Ch. 5 - In pharmacologic research a variety of clinical...Ch. 5 - Blood Chemistry In pharmacologic research a...Ch. 5 - A treatment trial is proposed to test the efficacy...Ch. 5 - A treatment trial is proposed to test the efficacy...Ch. 5 - A treatment trial is proposed to test the efficacy...Ch. 5 - Is the measure in Problem 5.38 a measure of...Ch. 5 - A treatment trial is proposed to test the efficacy...Ch. 5 - Refer to the pulmonary-function data in the Data...Ch. 5 - Prob. 43PCh. 5 - Refer to the pulmonary-function data in the Data...Ch. 5 - Prob. 45PCh. 5 - A clinical trial was conducted to test the...Ch. 5 - Well-known racial differences in blood pressure...Ch. 5 - Well-known racial differences in blood pressure...Ch. 5 - Prob. 49PCh. 5 - Suppose we observe 84 alcoholics with cirrhosis of...Ch. 5 - What is the probability of observing at least 29...Ch. 5 - Suppose we observe 84 alcoholics with cirrhosis of...Ch. 5 - FIGURE 5.22 Plasma-aldosterone concentrations in...Ch. 5 - FIGURE 5.22 Plasma-aldosterone concentrations in...Ch. 5 - Pregnant women with gestational diabetes mellitus...Ch. 5 - Officials in the State Health Department are...Ch. 5 - Prob. 57PCh. 5 - A study was conducted relating particulate air...Ch. 5 - Prob. 59PCh. 5 - Refer to Data Set VALID.DAT (at...Ch. 5 - Refer to Data Set VALID.DAT (at...Ch. 5 - Prob. 62PCh. 5 - A study concerned the risk of cancer among...Ch. 5 - Prob. 64PCh. 5 - A doctor diagnoses a patient as hypertensive and...Ch. 5 - A doctor diagnoses a patient as hypertensive and...Ch. 5 - Suppose the physician is not sure whether the...Ch. 5 - A study compared different treatments for...Ch. 5 - A study compared different treatments for...Ch. 5 - A study compared different treatments for...Ch. 5 - Obesity is an important determinant of...Ch. 5 - Prob. 72PCh. 5 - Prob. 73PCh. 5 - Prob. 74PCh. 5 - Prob. 75PCh. 5 - Prob. 76PCh. 5 - Answer the question in Problem 5.75 for a binomial...Ch. 5 - Prob. 78PCh. 5 - Prob. 79PCh. 5 - Prob. 81PCh. 5 - Prob. 82PCh. 5 - Prob. 83PCh. 5 - Prob. 85PCh. 5 - Retinitis pigmentosa (RP) is a genetic ocular...Ch. 5 - Prob. 87PCh. 5 - Prob. 88PCh. 5 - Prob. 89PCh. 5 - Physicians recommend that children with type-I...Ch. 5 - Physicians recommend that children with type-I...Ch. 5 - Prob. 92PCh. 5 - Prob. 93PCh. 5 - Prob. 94PCh. 5 - Prob. 95PCh. 5 - A previous study found that people consuming large...Ch. 5 - A previous study found that people consuming large...Ch. 5 - Prob. 98PCh. 5 - A study was recently published in Western...Ch. 5 - Prob. 100PCh. 5 - Prob. 101PCh. 5 - Prob. 102PCh. 5 - Prob. 103PCh. 5 - Prob. 104PCh. 5 - Prob. 105PCh. 5 - What is the 40th percentile of a normal...Ch. 5 - What is the sum of the 40th and 60th percentiles...Ch. 5 - What is z.90?Ch. 5 - A study was performed of different predictors of...Ch. 5 - A study was performed of different predictors of...Ch. 5 - Prob. 111PCh. 5 - Prob. 112PCh. 5 - Cancer The Shanghai Womens Health Study (SWHS) was...Ch. 5 - Prob. 114PCh. 5 - Prob. 115PCh. 5 - Prob. 116PCh. 5 - Prob. 117PCh. 5 - Prob. 118PCh. 5 - Prob. 119PCh. 5 - Prob. 120PCh. 5 - Prob. 121PCh. 5 - Prob. 122PCh. 5 - Prob. 123PCh. 5 - Prob. 124PCh. 5 - Hypertension Blood pressure readings are known to...Ch. 5 - Prob. 126PCh. 5 - Prob. 127PCh. 5 - Prob. 128PCh. 5 - Prob. 129PCh. 5 - Prob. 130P
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- Peak expiratory flow (PEF) is a measure of a patient’s ability to expel air from the lungs. Patients with asthma or other respiratory conditions often have restricted PEF. The mean PEF for children free of asthma is 306. An investigator conducts a study to investigate whether there is a difference in mean PEF in children with chronic bronchitis as compared to those without asthma or other respiratory conditions often have restricted PEF. Data on PEF are collected and summarized below. Based on the data, is there statistical evidence of a lower mean PEF in children with chronic bronchitis as compared to those without? Run the appropriate test at = 0.05. Group Number of Children Mean PEF Std PEF Chronic Bronchitis 25 281 68 No Bronchitis 25 319 74arrow_forwardPeak expiratory flow (PEF) is a measure of a patient’s ability to expel air from the lungs. Patients with asthma or other respiratory conditions often have restricted PEF. The mean PEF for children free of asthma is 306. An investigator conducts a study to investigate whether there is a difference in mean PEF in children with chronic bronchitis as compared to those without asthma or other respiratory conditions often have restricted PEF. Data on PEF are collected and summarized below. Based on the data, is there statistical evidence of a lower mean PEF in children with chronic bronchitis as compared to those without? Run the appropriate test at alpha = 0.05. Group Number of Children Mean PEF Std Dev PEF Chronic Bronchitis 25 281 68 No Chronic Bronchitis 25 319 74arrow_forward
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