The properties of dominant gain-of-function mutation. Introduction: The gene which controls the pattern of the body formation during early stages of embryonic development are known as homeotic genes. The homeotic genes encode the proteins that direct the cell to form various parts of the body.

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Chapter 23, Problem 12PDQ

Summary Introduction

To determine: The properties of dominant gain-of-function mutation.

Introduction: The gene which controls the pattern of the body formation during early stages of embryonic development are known as homeotic genes. The homeotic genes encode the proteins that direct the cell to form various parts of the body.

Summary Introduction

To determine: The process by which Antennapedia gene change antennae into legs.

Introduction: A homeotic gene is a gene that regulates the fate of certain areas of an animal’s body. The Drosophila species has eight homeotic genes, which are present on the same chromosome but are grouped into two complexes: the Antennapedia complex and the bithorax complex.

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The homeotic mutation Antennapedia causes mutant Drosophila to have legs in place of antennae and is a dominant gain of-function mutation. What are the properties of such mutations?How does the Antennapedia gene change antennae into legs?

Following a mutagenesis experiment to identify novel genes affecting the circadian clock in Drosophila melanogaster you discover several mutants. You start considering two of those mutants that you call C and d. The two homozygous C/C and d/d are arrhythmic (arrhythmic is the definition of their phenotype), whereas the two heterozygous C/C and D/d are rhythmic (rhythmic is the definition of their phenotype) with a 24h period. You make two true-breeding stocks: stock 3 homozygous for C and stock 4 homozygous for d. You cross them in both directions and in both cases you observe complementation with no difference between males and females. Then you take the progeny of one cross, for instance the F1 of Females 3 x Males 4, and you perform a Testcross. Out of 1000 flies resulting from the Testcross only 125 are rhythmic. Using the number of flies expected for the Parental and the Recombinant genotypes and the formula that defines recombination frequency, what is the distance between loci C…

Following a mutagenesis experiment to identify novel genes affecting the circadian clock in Drosophila melanogaster you discover several mutants. You start considering two of those mutants that you call c and d. The two homozygous c/c and d/d are arrhythmic (arrhythmic is the definition of their phenotype), whereas the two heterozygous C/c and D/d are rhythmic (rhythmic is the definition of their phenotype) with a 24h period. You make two true-breeding stocks: stock 3 homozygous for c and stock 4 homozygous for d. You cross them in both directions and in both cases you observe complementation with no difference between males and females. Then you take the progeny of one cross, for instance the F1 of Females 3 x Males 4, and you perform a Testcross. Out of 1000 flies resulting from the Testcross only 125 are rhythmic. Considering that out of 1000 flies resulting from the Testcross only 125 are rhythmic how many flies in total are approximatively expected for the Parental genotypes?…

Answer 2

Question

Chapter 23, Problem 12PDQ

Summary Introduction

To determine: The properties of dominant gain-of-function mutation.

Introduction: The gene which controls the pattern of the body formation during early stages of embryonic development are known as homeotic genes. The homeotic genes encode the proteins that direct the cell to form various parts of the body.

Summary Introduction

To determine: The process by which Antennapedia gene change antennae into legs.

Introduction: A homeotic gene is a gene that regulates the fate of certain areas of an animal’s body. The Drosophila species has eight homeotic genes, which are present on the same chromosome but are grouped into two complexes: the Antennapedia complex and the bithorax complex.

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Answer 3

Question

Chapter 23, Problem 12PDQ

Summary Introduction

To determine: The properties of dominant gain-of-function mutation.

Introduction: The gene which controls the pattern of the body formation during early stages of embryonic development are known as homeotic genes. The homeotic genes encode the proteins that direct the cell to form various parts of the body.

Summary Introduction

To determine: The process by which Antennapedia gene change antennae into legs.

Introduction: A homeotic gene is a gene that regulates the fate of certain areas of an animal’s body. The Drosophila species has eight homeotic genes, which are present on the same chromosome but are grouped into two complexes: the Antennapedia complex and the bithorax complex.

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Answer 4

Question

Chapter 23, Problem 12PDQ

Summary Introduction

To determine: The properties of dominant gain-of-function mutation.

Introduction: The gene which controls the pattern of the body formation during early stages of embryonic development are known as homeotic genes. The homeotic genes encode the proteins that direct the cell to form various parts of the body.

Summary Introduction

To determine: The process by which Antennapedia gene change antennae into legs.

Introduction: A homeotic gene is a gene that regulates the fate of certain areas of an animal’s body. The Drosophila species has eight homeotic genes, which are present on the same chromosome but are grouped into two complexes: the Antennapedia complex and the bithorax complex.

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Answer 5

Chapter 23, Problem 12PDQ

Summary Introduction

To determine: The properties of dominant gain-of-function mutation.

Introduction: The gene which controls the pattern of the body formation during early stages of embryonic development are known as homeotic genes. The homeotic genes encode the proteins that direct the cell to form various parts of the body.

Summary Introduction

To determine: The process by which Antennapedia gene change antennae into legs.

Introduction: A homeotic gene is a gene that regulates the fate of certain areas of an animal’s body. The Drosophila species has eight homeotic genes, which are present on the same chromosome but are grouped into two complexes: the Antennapedia complex and the bithorax complex.

Answer 6

Chapter 23, Problem 12PDQ

Summary Introduction

To determine: The properties of dominant gain-of-function mutation.

Introduction: The gene which controls the pattern of the body formation during early stages of embryonic development are known as homeotic genes. The homeotic genes encode the proteins that direct the cell to form various parts of the body.

Answer 7

Chapter 23, Problem 12PDQ

Summary Introduction

To determine: The properties of dominant gain-of-function mutation.

Introduction: The gene which controls the pattern of the body formation during early stages of embryonic development are known as homeotic genes. The homeotic genes encode the proteins that direct the cell to form various parts of the body.

Answer 8

Summary Introduction

To determine: The process by which Antennapedia gene change antennae into legs.

Introduction: A homeotic gene is a gene that regulates the fate of certain areas of an animal’s body. The Drosophila species has eight homeotic genes, which are present on the same chromosome but are grouped into two complexes: the Antennapedia complex and the bithorax complex.

Answer 9

Summary Introduction

To determine: The process by which Antennapedia gene change antennae into legs.

Introduction: A homeotic gene is a gene that regulates the fate of certain areas of an animal’s body. The Drosophila species has eight homeotic genes, which are present on the same chromosome but are grouped into two complexes: the Antennapedia complex and the bithorax complex.

Answer 10

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Answer 11

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Answer 12

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Answer 13

Ch. 23 - Suppose you initiate a screen for maternal-effect...Ch. 23 - Prob. 2NST Ch. 23 - Prob. 1CS Ch. 23 - Prob. 2CS Ch. 23 - Prob. 1PDQ Ch. 23 - Prob. 2PDQ Ch. 23 - Prob. 3PDQ Ch. 23 - Nuclei from almost any source may be injected into...Ch. 23 - Distinguish between the syncytial blastoderm stage...Ch. 23 - Prob. 6PDQ

The properties of dominant gain-of-function mutation. Introduction: The gene which controls the pattern of the body formation during early stages of embryonic development are known as homeotic genes. The homeotic genes encode the proteins that direct the cell to form various parts of the body.

Solution Summary: The author explains that homeotic genes regulate the fate of certain areas of an animal's body.

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