Biology (MindTap Course List)
11th Edition
ISBN: 9781337392938
Author: Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher: Cengage Learning
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Chapter 17.2, Problem 4LO
Summary Introduction
To describe: The features of Drosophila melanogaster, Caenorhabditis elegans, Mus musculus, and Arabidopsis thaliana that have made these organisms valuable models in developmental genetics.
Introduction: The growth and development of an organism are controlled by genes. Developmental genetics gives us insight into how these genes influence the growth and development of an organism. The patterns of morphogenesis in different species are investigated. Information necessary to build an organism is passed in the form of genes from one generation to the next.
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provide one example from the Drosophila AP toolkit for "Toolkit genes can be classified according to the phenotypes caused by their mutation. Similar mutant phenotypes often reflect genes that function in a single developmental pathway. Distinct pathways exist for the generation of body axes, for example, and for the formation and identity of fields."
Name three possible factors contributing to early asymmetries in a developing embryo (i.e. what are the kinds of things early on that lead to the development of the body axes - dn, a/p, l/r, etc)?
In the fruit fly drosophila melanogaster, the anterior-to-posterior body axis becomes segmented into distinct regions. explain the role of the genes bicoid and nanos in this process.
You have identified a Drosophila gene that is expressed exclusively in the odd-numbered "stripes" in the cellular blastoderm. Assuming that this gene is not redundant, what
would be the most likely phenotype cause by a loss-of-function mutation in this gene?
an embryo missing odd numbered segments
an adult fly with a second pair of wings instead of halteres
an embryo with two anterior ends
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an embryo missing larval segments 3-10
Chapter 17 Solutions
Biology (MindTap Course List)
Ch. 17.1 - Prob. 1LOCh. 17.1 - Describe the classic experiments of Steward,...Ch. 17.1 - Define stem cells, distinguish between embryonic...Ch. 17.1 - What lines of evidence support the principle of...Ch. 17.1 - Prob. 2CCh. 17.1 - What does the ability to produce iPSCs tell...Ch. 17.2 - Prob. 4LOCh. 17.2 - Prob. 5LOCh. 17.2 - Prob. 6LOCh. 17.2 - Prob. 7LO
Ch. 17.2 - Prob. 1CCh. 17.2 - Prob. 2CCh. 17.2 - Prob. 3CCh. 17.2 - Prob. 4CCh. 17.3 - Prob. 8LOCh. 17.3 - Prob. 1CCh. 17.3 - Prob. 2CCh. 17 - Prob. 1TYUCh. 17 - Prob. 2TYUCh. 17 - The anteriorposterior axis of a Drosophila embryo...Ch. 17 - Prob. 4TYUCh. 17 - Homeobox genes (a) are found in fruit flies but no...Ch. 17 - Prob. 6TYUCh. 17 - Prob. 7TYUCh. 17 - Which of the following statements about cancer is...Ch. 17 - Proto-oncogenes code for (a) morphogens (b)...Ch. 17 - Prob. 10TYUCh. 17 - Prob. 11TYUCh. 17 - Prob. 12TYUCh. 17 - CONNECT Why is an understanding of gene regulation...Ch. 17 - What is the reason that scientists study...Ch. 17 - Prob. 15TYUCh. 17 - Prob. 16TYUCh. 17 - EVOLUTION LINK What is the common ground between...Ch. 17 - INTERPRET DATA Flower parts are arranged in four...
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- What changes, if any, would you predict would occur in the pigmentation of Drosophila melanogaster with increased global warming? What type of genetic changes would you expect to see? Be as specific as you can.arrow_forwardIt seems that developmental genetics boils down to a complex network of gene regulation. Try to draw a structure of this network for Drosophila. How many genes do you think are necessary to complete the developmental network for the fruit fly? How many genes do you think are needed for a network to specify one segment? Do you think it is more difficult to identify genes that are involved in the beginning, middle, or end of this network? Suppose you were trying to identify all of the genes needed for development in a chicken. Knowing what you know about Drosophila development, would you first try to identify genes necessary for early development, or would you begin by identifying genes involved in cell differentiation?arrow_forwardCompare and contrast the experimental advantages and disadvantages of Drosophila, C. elegans, mammals, and Arabidopsis.arrow_forward
- Explain how loss-of-function mutations in the following categories of genes would affect the morphologies of Drosophila larvae: A. Gap genes B. Pair-rule genes C. Segment-polarity genesarrow_forwardIllustrate the chromosomes in the salivary gland of Drosophila melanogasterarrow_forwardA C. elegans (nematode) gene called par-1 helps todetermine the AP axis of the animal early in development. Scientists determined that par-1 is pleiotropic—it also has a later function in forming the vulva of theadult animal. How could researchers circumvent thelethality of par-1− mutants to observe the later function of the par-1 gene? (Hint: C. elegans larvae caneat bacteria expressing RNAi for any gene.)arrow_forward
- Compare and contrast the experimental advantages of Drosophila and C. elegans in the study of developmental genetics.arrow_forwardWhat would be the most likely effect on development of puncturing the posterior end of a Drosophila egg, allowing a small amount of cytoplasm to leak out, and then injecting that cytoplasm into the anterior end of another egg?arrow_forwardExpression of a homeotic gene in the wrong tissue in Drosophila results in the development of an inappropriate body part from that tissue. Explain why this happens and how it shows that homeotic genes are positive regulators of developmental pathways.arrow_forward
- Describe genetic studies which showed that yeastmitochondria are inherited biparentallyarrow_forwardBrainbow is a genetic approach to fate mapping developed to label cells with a seeming rainbow of possible colors, which can be used to identify each individual cell in a tissue or even a whole embryo. Give the mechanics behind this technique. What are its applications to the field of Biology in general, and to Developmental Biology in particular?arrow_forwardChristiane Nüsslein-Volhard and her colleagues carried out several experiments in an attempt to understand what determines the anterior and posterior ends of a Drosophila larva (reviewed in C. NüssleinVolhard, H. G. Frohnhofer, and R. Lehmann. 1987. Science 238:1675– 1681). They isolated fruit flies with mutations in the bicoid gene (bcd−). These flies produced embryos that lacked a head and thorax. When they transplanted cytoplasm from the anterior end of an egg from a wild-type female into the anterior end of an egg from a mutant bicoid female, normal head and thorax development took place in the embryo. However, transplanting cytoplasm from the posterior end of an egg from a wild-type female into the anterior end of an egg from a bicoid femalehad no effect. Explain these results in regard to what you know about proteins that control the determination of the anterior–posterior axis.arrow_forward
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