Genetic Analysis: An Integrated Approach (2nd Edition)
2nd Edition
ISBN: 9780321948908
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 13, Problem 22P
In humans that XX/XO mosaics, the phenotype is highly variable, ranging from females who have classic Turner syndrome symptoms to females who are essentially normal. Likewise, XX/XO mosaics have
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Females heterozygous for the recessive second chromosome mutations px, sp, and cn are mated to a male homozygous for all three mutations. The offspring are as follows:
Must show all work
1.) What gene is in the middle? and what are the map distances between the genes in centimorgans?
2.) What is the interference?
An individual is heterozygous for a reciprocal translocation, with the following chromosomes:
A • B C D E F
A • B C V W X
R ST • U D E F
R ST • U V W X
Q. Explain why the fertility of this individual is likely to be less than the fertility of an individual without a translocation.
L, R, P and D are four genes located on the same chromosome in a diploid
organism. Map distances between different pairs of genes were determined and
the following results obtained. Based on these data, what is the order of the
genes on the chromosome?
D-R: 35 CM
P-D: 5 CM
L-R: 10 CM
D-P: 30 CM
D-L 25 CM
P-R: 40 CM
Note that only one orientation of the order is given as an answer choice. For
example: ABCD has the same order as DCBA, but only ABCD would be listed
as a possible answer. So be sure to check both orientations when comparing
your gene order to the possible answer choices.
D-L-P-R
P-D-L-R
P-R-D-L
L-P-R-D
R-L-D-P
Chapter 13 Solutions
Genetic Analysis: An Integrated Approach (2nd Edition)
Ch. 13 - Prob. 1PCh. 13 - For one set of chromosomes carried by a triploid...Ch. 13 - 10.8 If the haploid number for a plant species is...Ch. 13 - From the following list, identify the types...Ch. 13 - Mating between a male donkey (2n=64) and a female...Ch. 13 - Prob. 6PCh. 13 - Prob. 7PCh. 13 - What can we conclude about a mutational event...Ch. 13 - 9. In terms of the chromosome content of nuclei,...Ch. 13 - 10. In Drosophila, an X-linked recessive allele...
Ch. 13 - The plants in this problem are the same as those...Ch. 13 - A normal chromosome and its homolog carrying a...Ch. 13 - 10.12 A pair of homologous chromosomes in...Ch. 13 - 10.13 An animal heterozygous for a reciprocal...Ch. 13 - Dr. Ara B. Dopsis has an idea he thinks will be a...Ch. 13 - Suppose polymerase chain reaction (PCR) is used...Ch. 13 - Prob. 17PCh. 13 - A healthy couple with a history of three previous...Ch. 13 - A boy with Down syndrome (trisomy 21) has 46...Ch. 13 - Prob. 20PCh. 13 - 10.28 A small population of deer living on an...Ch. 13 - In humans that XX/XO mosaics, the phenotype is...Ch. 13 - 10.20 A plant breeder would like to develop the...Ch. 13 - In Drosophilia, seven partial deletion (1to7)...Ch. 13 - Two experimental varieties of strawberry are...Ch. 13 - 10.23 In the tomato, Solanum esculentum, tall ()...Ch. 13 - In Drosophila, the wild-type red eye color is...Ch. 13 - A DrosophilaPelement 2.5kb in length is modified...Ch. 13 - A biologist studying flight mechanisms in insects...Ch. 13 - 30. After reading Experimental Insight and...Ch. 13 - 31. Two NotI restriction enzymes cleave DNA on...Ch. 13 - For the following crosses, determine as accurately...
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- For the following chromosome complements, what is the phenotypic sex of a person who has Q. XXYY with one copy of the SRY gene deleted?arrow_forwardBarr bodies are formed to adjust X chromosome dosage in species other than humans, such as Drosophila (fruit flies) and C. elegans (nematodes). True or False ?arrow_forwardHuman sex chromosomes are XX for females and XY for males. a. With respect to an X-linked gene, how many different types of gametes can a male produce? b. If a female is homozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele? c. If a female is heterozygous for an X-linked allele, how many different types of gametes can she produce with respect to this allele?arrow_forward
- In D. melanogaster, reduced bristles (rd), cinnabar eyes (cn), and vestigial wings (vg) are recessive traits located on chromosome II in that order. The distance between rd and cn is 7 cM and the distance between cn and vg is 9 cM. The CoC for this chromosome is 0.9. A true-breeding female expressing cinnabar eyes and vestigial wings is crossed to a true-breeding male expressing reduced bristles. The F1 are wild type. An F1 female is then test crossed to a male expressing all three traits. Among the F2 progeny, how often would you expect to observe flies expressing only cinnabar eyes? Using the same information from above, among the F2 progeny, how often would you expect to observe flies expressing only vestigial wings?arrow_forwardIn D. melanogaster, reduced bristles (rd), cinnabar eyes (cn), and vestigial wings (vg) are recessive traits located on chromosome II in that order. The distance between rd and cn is 7 cM and the distance between cn and vg is 9 cM. The CoC for this chromosome is 0.9. A true-breeding female expressing cinnabar eyes and vestigial wings is crossed to a true-breeding male expressing reduced bristles. The F1 are wild type. An F1 female is then test crossed to a male expressing all three traits. Among the F2 progeny, how often would you expect to observe flies expressing only cinnabar eyes? Using the same information from above, among the F2 progeny, how often would you expect to observe completely wild-type flies?arrow_forwardA boy with Down syndrome (trisomy 21) has 46 chromosomes. One parent and his two older sisters have a normal phenotype, but each have 45 chromosomes. a)Explain how this is possible. b)How many chromosomes do you expect to see in karyotypes of the parents? c)What term best describes this kind of chromosome abnormality? d)What is the probability the next child of this couple will have a normal phenotype and have 46 chromosomes? Explain your answer.arrow_forward
- For the following chromosome complements, what is the phenotypic sex of a person who has Q. XXY with the SRY gene deleted?arrow_forwardA PORTION OF THE LINKAGE MAP OF CHROMOSOME 2 IN THE TOMATO IS ILLUSTRATED HERE. ci (compound influorescence) o (oblate) - 15 CM 20 CM p (peach) THE OBLATE PHENOTYPE IS A FLATTENED FRUIT, THE PEACH PHENOTYPE IS HAIRY FRUIT (LIKE A PEACH), AND COMPOUND INFLORESCENCE MEANS CLUSTERED FLOWERS. IGNORE THE PEACH LOCUS. AMONG 1000 GAMETES PRODUCED BY A PLANT OF GENOTYPE O CI /+ +, WHAT TYPES OF GAMETES WOULD BE EXPECTED, AND WHAT NUMBER WOULD BE EXPECTED OF EACH?arrow_forwardFamilial Down syndrome is similar to primary Down syndrome in that it is caused by trisomy 21. However, in familial Down syndrome, all or part of the third copy of chromosome 21 has translocated onto another autosome, typically chromosome 14. In cases of familial Down syndrome, one of the parents of the affected child is often a carrier of a translocated chromosome. The translocation carrier parent does not have Down syndrome because he or she has a total of two copies of chromosome 21. Suppose that a woman is a translocation carrier of chromosome 21 on chromosome 14. She conceives six zygotes with a man who carries no aneuploidies. Match the description of the chromosomes inherited by each zygote with the viability and phenotype of the zygote. ✓ Two normal copies of 14, two normal copies of 21 two normal copies of 21, one normal copy of 14 ✓one normal copy of 14, one 21 to 14 translocation, one normal copy of 21 ✓two normal copies of 14, one normal copy of 21, on 21 to 14…arrow_forward
- Kuliev and Verlinsky (2004) state that there was a relatively high number of separation errors at meiosis I. In these cases the centromere underwent a premature division, occurring at meiosis I rather than meiosis II. Regarding chromosome 21, what would you expect to be the chromosome 21 complement in the secondary oocyte in which you saw a single chromatid (monad) for chromosome 21 in the first polar body? If this secondary oocyte was involved in fertilization, what would be the expected consequences?arrow_forwardAlthough most tortoiseshell cats are female, a litter of kittens will occasionally contain a male tortoiseshell. Which of the following can explain tortoiseshell coat color in a male kitten? Please explain in detail. The male kitten has an extra Y chromosome The male kitten has an extra X chromosome The male kitten has no X chromosome The male kitten cannot carry out X-inactivationarrow_forwardA diploid species has 3 pairs of chromosomes in its somatic cells. In males, the first pair is large submetacentric[1]; the second is medium acrocentric[2], and the third is small telocentric[3]. In females, the first two pairs are like those of the males while the third is large metacentric[4][5], with satellite4 Illustrate the karyograms (drawing/picture of the chromosome) of the following: A triploid cell in females tetrasomic cell in males tetraploid cell in females [1] submetacentric --centrosome is just above the middle of the chromosome [2] acrocentric --centrosome is much higher location than submetacentric so that the “p” arm of the chromosome is much shorter than the q arm [3] telocentric --the centromere is at the end of the chromosome [4] metacentric --centrosome is in the middle of the chromosome; thus the “p-arm” and the “q-arm” or both arms of the chromosome are equal in length [5] satellite-a constriction in an arm of a chromosome, aside…arrow_forward
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