EBK VISUAL ANATOMY & PHYSIOLOGY
3rd Edition
ISBN: 9780134454658
Author: Petti
Publisher: PEARSON CUSTOM PUB.(CONSIGNMENT)
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Question
Chapter 11.2, Problem 2I
Summary Introduction
To describe: If there will be an action potential that will be generated if the resting membrane potential is at the threshold level of -60mV.
Introduction: The presynaptic cell releases the neurotransmitters that are able to depolarize the postsynaptic membrane; this is called excitatory postsynaptic potential (EPSP).
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Describe the contribution of each of the following to the establishment and maintenance of membrane potential:
Part A
Na+K+ Pump
Passive movement of K+ across the membrane
Passive movement of Na+ across the membrane
Part B
Resting membrane potential is approximately -70mV. Explain what resting membrane potential is and what -70mV refers to.
You are recording from a cell with a resting
membrane potential of -65 mV. You inject 100
pA of current, resulting 58.7 mV.
What is the value of tau? With this in mind, what
is the capacitance of the cell? Please provide
relevant equations to illustrate your thought
process.
When you terminate the current injection, how
long do you expect for it to take for the cell to
repolarize to -63 mV?
Draw details of the repolarization phase of an action potential from the following descriptions of the sequences of AfterHyperPolarization (AHP) and AfterDePolarization (ADP) sequences. Make the distinct phases clear and noticeable (5 % each)
A complex AHP consisting of a first component AHP, an ADP, and a second component AHP before repolarization to resting membrane potential
a first fast AHP component, followed by a slower AHP, followed by a fast ADP, and a second late AHP component before repolarization to rest
Chapter 11 Solutions
EBK VISUAL ANATOMY & PHYSIOLOGY
Ch. 11.1 - Prob. 1RCh. 11.1 - Prob. 2RCh. 11.1 - Prob. 3RCh. 11.1 - Prob. 4RCh. 11.1 - Prob. 5RCh. 11.1 - Prob. 6RCh. 11.1 - Prob. 7RCh. 11.1 - Prob. 8RCh. 11.1 - Prob. 9RCh. 11.1 - Prob. 10R
Ch. 11.1 - Prob. 11RCh. 11.1 - Prob. 1LOCh. 11.1 - Prob. 2LOCh. 11.1 - Prob. 3LOCh. 11.1 - Prob. 4LOCh. 11.1 - Prob. 5LOCh. 11.1 - Prob. 1ICh. 11.1 - Prob. 2ICh. 11.1 - Prob. 3ICh. 11.1 - Prob. 1SRCh. 11.1 - Labeling: Label each of the structures in the...Ch. 11.1 - Labeling: Label each of the structures in the...Ch. 11.1 - Prob. 4SRCh. 11.1 - Prob. 5SRCh. 11.1 - Prob. 6SRCh. 11.1 - Prob. 7SRCh. 11.1 - Prob. 8SRCh. 11.1 - Prob. 9SRCh. 11.1 - Prob. 10SRCh. 11.1 - Prob. 11SRCh. 11.1 - Prob. 12SRCh. 11.1 - Prob. 13SRCh. 11.1 - Prob. 14SRCh. 11.1 - Prob. 15SRCh. 11.1 - Prob. 16SRCh. 11.1 - Prob. 17SRCh. 11.1 - Prob. 18SRCh. 11.1 - Prob. 19SRCh. 11.1 - Prob. 20SRCh. 11.2 - Define membrane potential.
Ch. 11.2 - Prob. 2RCh. 11.2 - Prob. 3RCh. 11.2 - Prob. 4RCh. 11.2 - Prob. 5RCh. 11.2 - Prob. 6RCh. 11.2 - Prob. 7RCh. 11.2 - Prob. 8RCh. 11.2 - Prob. 9RCh. 11.2 - Prob. 10RCh. 11.2 - Prob. 11RCh. 11.2 - Prob. 12RCh. 11.2 - C. Compare the absolute refractory period with the...Ch. 11.2 - Prob. 14RCh. 11.2 - Prob. 15RCh. 11.2 - Prob. 16RCh. 11.2 - Prob. 17RCh. 11.2 - Prob. 18RCh. 11.2 - Prob. 19RCh. 11.2 - Prob. 20RCh. 11.2 - Prob. 21RCh. 11.2 - Prob. 22RCh. 11.2 - Prob. 23RCh. 11.2 - Describe the general role of membrane potential...Ch. 11.2 - Explain how the resting membrane potential is...Ch. 11.2 - Describe the functions of gated ion channels with...Ch. 11.2 - Describe graded potentials.
Ch. 11.2 - Prob. 5LOCh. 11.2 - Describe continuous propagation and saltatory...Ch. 11.2 - Describe the general structure of synapses in the...Ch. 11.2 - Discuss the significance of postsynaptic...Ch. 11.2 - Discuss the interactions that make information...Ch. 11.2 - Prob. 1ICh. 11.2 - Prob. 2ICh. 11.2 - Prob. 3ICh. 11.2 - Vocabulary: Write the term for each of the...Ch. 11.2 - Vocabulary: Write the term for each of the...Ch. 11.2 - Vocabulary: Write the term for each of the...Ch. 11.2 - Vocabulary: Write the term for each of the...Ch. 11.2 - Vocabulary: Write the term for each of the...Ch. 11.2 - Vocabulary: Write the term for each of the...Ch. 11.2 - Vocabulary: Write the term for each of the...Ch. 11.2 - Vocabulary: Write the term for each of the...Ch. 11.2 - Short answer: For the following diagram of a...Ch. 11.2 - Section integration: Guillain-Barré (ghē-YAN...Ch. 11 - Prob. 1CRQCh. 11 - Prob. 2CRQCh. 11 - Prob. 3CRQCh. 11 - Prob. 4CRQCh. 11 - Prob. 5CRQCh. 11 - Prob. 6CRQCh. 11 - Prob. 7CRQCh. 11 - Prob. 8CRQCh. 11 - Prob. 9CRQCh. 11 - Prob. 10CRQCh. 11 - Prob. 11CRQCh. 11 - Prob. 12CRQCh. 11 - Prob. 13CRQCh. 11 - Prob. 14CRQCh. 11 - Prob. 15CRQCh. 11 - Prob. 16CRQCh. 11 - Prob. 17CRQCh. 11 - Prob. 18CRQCh. 11 - Prob. 19CRQCh. 11 - Prob. 20CRQCh. 11 - Prob. 21CRQCh. 11 - Prob. 22CRQCh. 11 - Prob. 23CRQCh. 11 - Prob. 24CRQCh. 11 - Prob. 25CRQCh. 11 - Prob. 26CRQCh. 11 - Prob. 27CRQCh. 11 - Prob. 28CRQCh. 11 - Prob. 29CRQCh. 11 - What three functional classes of neurons are found...Ch. 11 - Prob. 31CRQCh. 11 - Prob. 32CRQCh. 11 - Prob. 33CRQCh. 11 - Prob. 1CICh. 11 - Prob. 2CICh. 11 - Prob. 3CI
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- Conformational changes in channel proteins brought about by voltage changes are responsible for opening and closing Na+ and K+ gates during the generation of an action potential. (True or false?)arrow_forwardAssume presynaptic excitatory neuron A terminates on a postsynaptic cell near the axon hillock and presynaptic excitatory neuron B terminates on the same postsynaptic cell on a dendrite located on the side of the cell body opposite the axon hillock. Explain why rapid firing of presynaptic neuron A could bring the postsynaptic neuron to threshold through temporal summation, thus initiating an action potential, whereas firing of presynaptic neuron B at the same frequency and the same magnitude of EPSPs may not bring the postsynaptic neuron to threshold.arrow_forwardAt the peak of the neuronal action potential, Vm is approximately +50 mV. Assuming normal intracellular and extracellular K+ concentrations ( [K+]o = 4 mM, [K+]i = 150 mM ), what is the driving force (in mV) that acts on K+ ions at the peak of the action potential?arrow_forward
- What kind of graded potential describes a change in membrane potential from 70 to 60 mV? From 70 to 80 mV?arrow_forwardDraw the current that you would expect to flow during a voltage clamp experiment on a typical neuron. Voltages and time course are shown. Briefly explain why the currents are inward or outward. Be sure to provide scale bars. You should definitely label the Y axis so that the peak current value is obvious. Draw the Na+ current you would expect if there were physiological ionic gradients. Draw the K+ current you would expect if there are physiological ionic gradients. Draw the K+ current you would expect if the bath solution and the intracellular solution are both 125 mM.arrow_forwardSeparately, draw a table using arrows to depict the appropriate magnitude and direction of the forces and ion fluxes at different membrane potentials for a ligand-gated channel that is equally permeable to both ion X+ and ion Y+. The equilibrium potential for ion X+ is -60 mV, and the equilibrium potential for ion Y+ is -20 mV. Which item best represents the forces and fluxes for a membrane potential of 0 mV?arrow_forward
- What is the equilibrium membrane potential due to Na+ ions if the extracellular concentration of Na+ ions is 154 mM and the intracellular concentration of Na+ ions is 27 mM at 20 ∘C ? Please answer asap and in short and content should not be palgarised pleasearrow_forwardSeparately, draw a table using arrows to depict the appropriate magnitude and direction of the forces and ion fluxes at different membrane potentials for a ligand-gated channel that is equally permeable to both ion X+ and ion Y+. The equilibrium potential for ion X+ is -60 mV, and the equilibrium potential for ion Y+ is -20 mV. Which item best represents the forces and fluxes for a membrane potential of -40 mV (a, b, c, or d)? Upwards arrows means outward direction and downwards arrow means inward direction. The length of the arrow determines the magnitude.arrow_forwardMatch the description with the statement that best describes the following statements hyperpolarization repolarization depolarization A. usually corresponds to opening of voltage-gated potassium channels B. any change in the membrane potential that moves the membrane potential to a value more positive than the resting potential (eg from -70mV to +35mV) C. any change in the membrane potential that moves the membrane potential to a value more negative than the resting potential (eg from -70mV to -85mV)arrow_forward
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