The average allele frequency will be weighted by the proportion of the allele frequency in males and females: Where: 1 2 p=3 Pm (t) + Pf(t) Pm (t) = the allele frequency in males at time t Pf(t) = the allele frequency in females at time t We also showed the following: Pm (t+1)= pr(t) Pm (t) + pf(t) 2 These are the allele frequencies in males and females at time t+1. Pf(t+1) = Lastly these can be used to determine the genotype frequencies for females in generation t+1 for a sex- linked locus assuming HWE: P₁1(t+1)= Pm (t)pf (t) P12(t+1)= Pm (t)am(t) + am (t)pf (t) P22(t+1)= 9m (t)qf(t) Here is the problem. Consider and X-linked locus with two alleles A1 and A2. Allele A₁ has an initial allele frequency of 1.0 in females and 0 in males. Use a spreadsheet (Excel) and its graphing functions to calculate the allele frequencies in males and females for 25 generations. Also plot the expected genotype frequencies in females for 25 generations. -How long does it take for allele frequencies to reach equilibrium? -How long does it take for female genotypes to reach equilibrium?

The average allele frequency will be weighted by the proportion of the allele frequency in males and females: Where: 1 2 p=3 Pm (t) + Pf(t) Pm (t) = the allele frequency in males at time t Pf(t) = the allele frequency in females at time t We also showed the following: Pm (t+1)= pr(t) Pm (t) + pf(t) 2 These are the allele frequencies in males and females at time t+1. Pf(t+1) = Lastly these can be used to determine the genotype frequencies for females in generation t+1 for a sex- linked locus assuming HWE: P₁1(t+1)= Pm (t)pf (t) P12(t+1)= Pm (t)am(t) + am (t)pf (t) P22(t+1)= 9m (t)qf(t) Here is the problem. Consider and X-linked locus with two alleles A1 and A2. Allele A₁ has an initial allele frequency of 1.0 in females and 0 in males. Use a spreadsheet (Excel) and its graphing functions to calculate the allele frequencies in males and females for 25 generations. Also plot the expected genotype frequencies in females for 25 generations. -How long does it take for allele frequencies to reach equilibrium? -How long does it take for female genotypes to reach equilibrium?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter19: Population Genetics And Human Evolution

Section: Chapter Questions

Problem 9QP: Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic...

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