Question 1 Amyloid Precursor Protein (APP) is actually thought to be a natural neuroprotective agent induced by neuronal stress or injury. True O False Question 2 Which of the following is not a property of serine protease? A globular protein with high molecular weight It is initially synthesized as a zymogen It has uniquely activated tyrosine residue at the active site Cleaves polypeptide at a specific amino acid residue Question 3 RTK is activated by cyclic AMP. True False
Q: 1. Given the following metabolic pathway of aspartate to pyruvate, all of which occurs in the…
A: Since you have posted multiple questions, we will provide the solution only to the first question as…
Q: Discuss the cellular location and biological significance of the processes of the citric acid cycle…
A: Cellular respiration is a collection of three metabolic pathways that generate ATP by the oxidation…
Q: The Cori cycle involves the: OA) conversion of glucose to lactate in liver and lactate to glucose in…
A: The Cori cycle is also known as the lactic acid cycle. During muscular activity, when oxygen supply…
Q: In TCA cycle, FADH2 is formed in reaction(s) catalyzed by a. Succinyl-CoA synthetase O b. Succinate…
A: In aerobic condition, pyruvate in the presence of pyruvate dehydrogenase complex produces Acetyl…
Q: Describe how the activity and specificity of ribonucleotide reductase (RNR) is regulated.
A: Ribonucleotide reductase (RNR) catalyzes the rate-limiting step in the only known de novo pathway…
Q: Which one of the statements below best describes the mechanism of proton translocation by the…
A: The Q cycle (named after quinol) is a set of reactions. The Q cycle describes how the sequential…
Q: What is the dissociation equilibrium constant of a protein if the concentration of free ligand is…
A: Consider the following reaction: P + L ⇌k2k1 PL where P is the protein, L is the ligand and k1 and…
Q: 1. Carbohydrates a. If lactose were to react with an acid or an enzyme within the gastric system,…
A: Chemically, carbohydrates are polyhydroxy aldehydes or ketones. They have the general formula :…
Q: Why stachyose can be used as prebiotic??how is the chemical structure of stachyose affect bacteria?
A: Chemically carbohydrates are polyhydroxy aldehydes or ketones. They have the general formula :…
Q: In the first stage of glycolysis, the hydroxyl group on C6 of glucose is phosphorylated to form…
A: Glycolysis is takes place in both the cells aerobic and anerobic as it does not utilize oxygen to…
Q: What is the molecular basis for the difference in the electrophorentic pattern between normal…
A: Hemoglobin is a globular protein, ie it is roughly spherical. It is a tetramer of two types of…
Q: OXIDATIVE PHOSPHORYLATION: 3A) Thoroughly explain the biological significance of NADH/H* and FADH2…
A: All life forms require energy. We obtain this energy from the food we eat. It is the highly reduced…
Q: Draw the structure of the a-methyl-pyranoside form of mannose following the reaction of the sugar…
A: Carbohydrates are polyhydroxy aldehydes or ketones. They can be classified as monosaccharides,…
Q: Why is it more accurate to call the pathway that converts acetyl-CoA to COA + 2 CO₂ the citrate…
A: The pathway that converts the acetyl coA to coA and carbon dioxide is called citric acid cycle or…
Q: ATP is the primary source of cellular energy. What qualities of ATP make it a useful energy…
A: ATP acts as the “energy currency” of the cell. The energy that is released during fuel oxidation in…
Q: Que Tuesday, December well Faudos *The amino acid alanine can be used as an energy source. alanine…
A: Alanine is a glucogenic amino acid, which synthesizes the precursor for glucose synthesis during its…
Q: What charge does a protein molecule have? O neutral O positive O negative O The charge depends on…
A: Diffusion and osmosis are 2 processes that depict the movement of substances from higher…
Q: Task #3: Design primers 1 agagtctcct cagacgccga gatgctggtc atggcgcccc gaaccgtcct cctgctgctc 61…
A: A primer is a short single-stranded nucleotide chain used for the initiation of DNA synthesis. In…
Q: QUESTION 21 Match the following metabolic reactions or components with their corresponding cellular…
A: Since you have posted multiple questions, we will provide the solution only to the first question as…
Q: Part A Determine the amino acid sequence of a peptide section of beta-amyloid containing 10 amino…
A: Amino acid sequences are written with N-terminal amino acid on the left and C-terminal amino acid on…
Q: Cell signaling systems: A. autocrine B. paracrine C. endocrine D. none among the…
A:
Q: AG" for reaction A B = -10 kJ/mol AG" for reaction BC = -8 kJ/mol AG" for reaction CD = 5 kJ/mol AG"…
A: The standard free energy change (∆G°) of a chemical reaction is the free energy change at the…
Q: Reciprocal regulation of opposing pathways is necessary to avoid the wasteful synthesis and…
A: Metabolism is the total of all chemical transformation that takes place in a living cell. One…
Q: Which of the following is a substrate from primase?
A: DNA/RNA are nucleic acids, the molecules responsible for carrying genetic information from one…
Q: The total degradation of a fatty acid with an odd number of carbons yields acetyl-CoA and another…
A: Fatty acids are carboxylic acids with a hydrocarbon chain ranging from 4 carbon to 36 carbons.…
Q: The enzyme that decarboxylates pyruvate before it gets converted to Acetyl CoA is a. Pyruvate…
A: Citric acid cycle is a metabolic pathway that converts carbon atoms to CO2 and, in doing so,…
Q: true or false: Guanylate phosphorylase is responsible for converting guanosine monophosphate into…
A: Nucleosides are pentose sugar linked to heterocyclic nitrogenous bases. Nucleotides are phosphoric…
Q: *While acetyl-SCOA activates pyruvate carboxylase, it inhibits pyruvate kinase. Explain how this is…
A: Complementary control is a type of metabolic regulation by which 2 complementary pathways are…
Q: Which of the following amino acid side chains CANNOT form hydrogen bond? O a. Gln O b. Tyr O C. O d.…
A: Amino acids contain amino group and carboxyl group along with R side chain. The R side chain defines…
Q: A patient with chronic pancreatitis and hence decreased secretory function of pancreas was…
A: Individual having an inflammation in the pancreas which does not improve over a long period of time…
Q: If the AH for a reaction is -4 kJ/mol and the AS is 20 J/(molK), which of the following statements…
A: Standard free energy of a reaction is calculated in order to quantify the spontaneity of a reaction…
Q: During phototransduction, the molecular processing in retinal rods under light activates mechanism…
A: Rods and cones are the two types of photoreceptors that are distributed in the retina. Rods are very…
Q: A characteristic of complex III is that it is reduced by FADH2. participates in electron transfer…
A: ETC consist of four protein complexes called Complex I, II, III and IV that transport electron…
Q: The sequence of part of an mRNA transcript is What is the sequence of the DNA coding strand? 5'- 5'…
A: DNA is double stranded & during replication both of its strands unwind to produce single…
Q: What is the correct order, from highest content to lowest content, for triacylglycerols in the…
A: Lipoproteins are droplets of fats that are surrounded by a single layer of phospholipid molecules.…
Q: How do enhancers differ from promoters? Enhancers do not bind RNA polymerase. Enhancers include the…
A: Transcription requires an enzyme called RNA polymerase that catalyses the transcription. Prokaryotic…
Q: A drug with an elimination half-life of 1 hour was given to a male patient weighing 60 g by IV at…
A: Given, Rate of administration IV (R) is 300 mg/hr Plasma drug concentration at 7 hours was (C) 11…
Q: If the range of the graph in the first part of the question is supposed to be between 5 and 10,…
A: Changes in pH affect the ionisation of active site residues of an enzyme and alters the rate of…
Q: Metabolic enzymes are often found in large multi-enzyme complexes. What are the benefits of this…
A: Enzymes are biological catalysts that catalyse biochemical reactions. Substrates bind to the free…
Q: (a) A pathway consists of 6 enzymes (p, q, r, s, t, u) that convert substrate J to product X at a…
A: Metabolic pathways are a series of biochemical reactions that convert one biomolecule into another.…
Q: Glycogenolysis requires which of the following combination of enzymes? OA) Glycogen synthase and…
A: Glycogen is a storage polysaccharide consisting of D-glucose residues in which glucose residues are…
Q: How does the binding of a hormone to a receptor activate a G-protein? a. It replaces bound GDP…
A: G Protein Coupled Receptors These are also called metabotropic receptors or heptahelical…
Q: Q2. Circle true or false for each stat ni bavlovni smyno sto siqmsxs n6 zi sbimsoqu 1) T F Oxygen…
A: Since you have posted multiple questions, we will provide the solution only to the first five…
Q: Coenzyme A is: A) a form of cellular energy. OB) an anabolic electron carrier. C) a catabolic…
A: Cells convert energy into small, energy-rich molecules such as ATP and nicotinamide adenine…
Q: In extracellular proteins the amino acid Cys can interact with another Cys to form a bond sometimes…
A: Proteins are composed of amino acids, which are bound together by peptide linkage. Amino acids…
Q: Growth is an example of a ________ process. metabolic generative responsive control
A: Metabolism is the process of breakdown of complex biomolecules in food, in order to release energy.…
Q: Beer’s Law: In serum cholesterol analysis, if the grad. cylinder that measured the acetic acid…
A: A spectrophotometer can measure the amount of light absorbed by a biomolecule and we can use that…
Q: How are soaps made? Draw the full saponification reaction between potassium hydroxide and a…
A: Lipids are one of the 4 biomacromolecules. Majority fraction of a lipid molecule would be…
Q: Glycogen is the main storage form of glucose in animals. Why is glucose necessary as opposed to…
A: Osmolarity is the product of van't Hoff factor (i) and solute concentration. van't Hoff factor tells…
Q: Explain the rationale of dissolution of drugs according to pH? What is the pH of gastric fluid? What…
A: Dissolution of drugs is the process by which drugs dissolve in a liquid medium (generally the…
Step by step
Solved in 4 steps
- Question 6 of 19 Proteasomal proteases can be inhibited by compounds such as ixazomib (shown below). How does this compound inhibit protease activity? HO Ixazomib O Uncomptetitively O Competitively O NoncompetitivelyQUESTION 10 Select a property that does not belong to allosteric enzymes. They conform to hyperbolic Michaelis-Menten kinetics They may have binding sites for regulatory molecules that are separate from active sites They tend to have a signmoidal curve of rate versus [S] They undergo conformation changes as a result of modulator binding.Question 14 The folding of an unfolded protein proceeds from low entropy disordered state to a single high entropy, low energy native conformation O True O False Question 15 The GroES subunit has 14 identical 549-residue subunits arranged in two stacked rings with 7 subunits eac True False
- Question 8 Which statement about N-linked glycosylation is correct? O N-linked oligosaccharides are attached to proteins one sugar at the time in the endoplasmicreticulum. O N-linked sugars are attached to proteins as a 14 residue oligosaccharide during translation in the endoplasmic reticulum. O N-linked sugars are attached to proteins as a 14 residue oligosaccharide during translation inthe cytoplasm. O N-linked sugars are attached to proteins as a 14 residue oligosaccharide after translation inthe Golgi apparatus.Question 1Predicting Secondary Structure Which of the following peptides is more likely to take up an -helical structure, and why? (a) LKAENDEAARAMSEA (b) CRAGGFPWDQPGTSNQuestion 4. Imagine the main chain of a protein bends back on itself so that two amino acid residues R1 and R2 come close to each other. In the table below are four possibilities for what R1 and R2 might be. In each case, decide whether a specific interaction could form between the residues. If a specific interaction could form, give the name of the interaction. R₁ cysteine tyrosine threonine arginine R₂ cysteine phenylalanine glutamine aspartate specific interaction? OO yes O yes O no no OO O yes no yes no name of specific interaction 0 П 0 0
- 5 pts Question 9 95 58 40 HS HS SH 65 8 M urea and 72 B-mercaptoethanol 65 Hs84 Hs- SH 72 26 HS 110 SH 84 26 110 95 124 40 58 Native ribonuclease Denatured reduced ribonuclease Figure 2.53 Biochemistry, Seventh Edition O 2012 W. H. Freeman and Company The image above shows how Anfinsen unfolded ribonuclease for his classic experiment to see if proteins contain all necessary information for adopting their folded states on their own. To achieve proper refolding and ribonuclease activity, Anfinsen must have: trick question: ribonuclease cannot adopt its folded state without the help of cellular machinery removed the mercaptoethanol followed by the urea very carefully removed both the urea and mercaptoethanol at the same time removed the urea followed by the mercaptoethanolQuestion (2rarate nusCollagenase is an endopeptidase that digest native collagen in the triple helix region. The diagram below shows the kinetic plot of collagenase with varied substrate concentration. Plot collagenase activity in response to substrate concentration and find approximate values for Vmax and Km. (please indicate your assumption/s accordingly for this question) 0,04 0,035 0 luM) 0,03 O 200 (uM) 0,025 X 270 (uM) 0.02 A 350 (uMI 0,015 0.01 0,005 On 10 20 30 50 60 Collagenase [pg/ml] Collagenase activity [mM/min]Question 13 About the protein structure: |A The primary structure of a protein corre- sponds to its sequence and is always writ- ten from its C-terminus to its N-terminus. B The secondary structures of a protein are formed by hydrophobic bonds between the different atoms of the main chain. C The quaternary structure of a protein in- volves only covalent bonds established be- tween the different peptide chains. D The tertiary structure of a protein in- volves, among other things, hydrogen and ionic bonds between the side chains of the different amino acid residues. E None of the above statements is right.
- QUESTION 4 What TYPE of inhibition is observed in the following: S E Competitive Non-competitive Uncompetitive AllostericEffects of BPA on phosphorylation of MAPKfamily in RAW264.7 cells conclusionHydropathy & Amphipathicity 2 -1 -2- 110 210 310 410 510 Residue Number C. Draw the topology of this membrane protein in the bilayer and indicate the range of residues forming transmembrane a-helices.