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How do you promote cellular regulation in a patient with impaired kidney
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- The principle of dialysis is employed in artificial kidneys. How do you think this dialysis works?In a person with diabetes mellitus, what would be causing polyuria? Glucose has saturated the secondary active transporters in the PCT that move glucose into the cells, increasing the concentration gradient between the filtrate and the ISF or Glucose has saturated the secondary active transporters in the PCT that move glucose into the cells, reducing the concentration gradient between the filtrate and the ISFa. A person ingests an ion-channel inhibitor, such that the ion channels present in the Loop of Henle are only able to pump at half their normal rate? b. What would this person notice about changes to their physiological filtration? (Answer a and b)
- Epithelial cells that reabsorb solutes are cuboidal, but epithelial cells involved in filtration are thin, squamous cells. The cuboidal cells contain more cytoplasm and organelles, especially mitochondria and rough endoplasmic reticulum (RER), than the squamous cells. Why do the cuboidal cells of the kidney tubules need more mitochondria and RER?Which of the following is an example of autoregulation of kidney function? a. The RAAS regulates Na1 by secreting renin when blood pressure or blood volume decreases. b. The ADH system regulates water balance by decreasing water reabsorption and increasing excretion of salt. c. Receptors in the juxtaglomerular apparatus detect a higher salt concentration in the distal convoluted tubule and trigger constriction of the afferent arteriole to reduce glomerular filtration rate. d. ANF is released by the kidney to increase renin release. e. Angiotensin II lowers blood pressure by constricting arterioles.Which of the following does not contribute to the process of filtration? (a) active transport by epithelial cells lining renal tubules (b) large surface area for filtration (c) low permeability of glomerular capillaries (d) high hydrostatic blood pressure in glomerular capillaries (e) podocytes
- Which of the following protein types would you predict is defective in kidney water balance disorders? Na+/K+ pump anion exchange protein ATPase GLUT1 aquaporin35. Identify the osmolality (including units) of MOST body fluids (cytosol, ISF, blood, CSF, etc.) vs. the osmolality range created and maintained in the renal medulla ISF by the countercurrent mechanism. Include the units. I Most body fluids except urine Renal medulla ISF UrineWhy is beta blocker not used for patients with renal disease? Please explain at your own words.
- sodium potassium pumps are the driving force behind whatHow does adh regulate kidney function? Please include blood osmolarity, the hypothalamus, adh, permeability of kidney, homeostasis and h20 reabsorption increasing in the explanationWhy patients with diabetes can experience significant changes in blood osmolality?