Gastro-oesophageal reflflux SCENARIO Jim is a three-month-old baby born at 35 weeks’ gestation. He has been in hospital since birth with a variety of problems. He is now feeding enterally via a bottle, but is not thriving and his weight is falling off the centile chart. He has been on feed thickeners and ranitidine for the last month for gastro-oesophageal reflflux, but symptoms still persist. QUESTIONS: Jim gets an ear infection and is started on metronidazole suspension. The current reflux regimen continues. 1. What is the problem of using metronidazole suspension when the gastric content is acid suppressed? 2. What is the other potential risk of using metronidazole alongside ranitidine suspension?

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter15: Adult And Pediatric Dosages Based On Body Weight
Section: Chapter Questions
Problem 37SST
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Gastro-oesophageal reflflux SCENARIO Jim is a three-month-old baby born at 35 weeks’ gestation. He has been in hospital since birth with a variety of problems. He is now feeding enterally via a bottle, but is not thriving and his weight is falling off the centile chart. He has been on feed thickeners and ranitidine for the last month for gastro-oesophageal reflflux, but symptoms still persist. QUESTIONS: Jim gets an ear infection and is started on metronidazole suspension. The current reflux regimen continues. 1. What is the problem of using metronidazole suspension when the gastric content is acid suppressed? 2. What is the other potential risk of using metronidazole alongside ranitidine suspension? 3.What is the rationale of use of these products? 4. Briefly mention the potential issues surrounding the use of each product.
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