1. Propose reagents to achieve the following transformation. Hint: If you want to use an enolate, you need to do that first, while you still have a carbonyl. OH
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- Fill the reagents, a through f in the following synthesisAldol condensation is a reversible reaction and in fact aldols can be transform into the starting carbonyl compounds. Complete using arrows, the following retroaldol reactionPropose a synthesis of the following compound and any other reagent that you need.
- Draw the reagents and solvent necessary to conduct the following reaction. ( You may need to use more than one step to accomplish the transformations). DRAW ALL REAGENTS, SUBSTRATE, AS WELL AS THE PRODUCT OF EACH STEP.draw the mechanism for all 3 steps Propose a plausible mechanism for the following transformation. This reaction will appear later in this chapter, so practicing the mechanism now will serve as preparation for the rest of this chapter. xs NH CI NH2 Step 0 Correct. These are not acidic conditions, so the mechanism begins with nucleophilic attack and has three steps overall: 1) nucleophilic attack, 2) loss of a leaving group, and 3) deprotonation. Identify the most likely sequence of steps in the mechanism. Deprotonation, followed by concerted Nucleophilic attack and Loss of a leaving group Deprotonation, Nucleophilic attack, Loss of a leaving group Nucleophilic attack, Loss of a leaving group, Deprotonation Concerted Nucleophilic attack and Loss of a leaving group, followed by Deprotonation Step 1 X Incorrect. Add curved arrow(s) to draw step 1 of the mechanism. Modify the given drawing of the product as needed to show the intermediate that is formed in this step. Use the +/- tools to…In a presence of a base, which of the following will not form an enolate? A) B) OEt OEt OEt C) D) OEt O A C.
- How do I draw a synthesis for this reaction3. Propose a possible synthetic pathway for the following reaction. multiple stepsDraw the reagents and solvent necessary to conduct the following reactions. ( You may need to use more than one step to accomplish the transformations). DRAW ALL REAGENTS, SUBSTRATE, AS WELL AS THE PRODUCT OF EACH STEP.