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1 Mus 2 Canis 3 Bos 4 G-gamma 5 A-gamma 6 gamma 7 epsilon 8 fetal 9 beta consensus/100% consensus/90% consensus/80% consensus/70% 1 Mus 2 Canis 3 Bos 4 G-gamma 5 A-gamma 6 gamma 7 epsilon 8 fetal 9 beta consensus/100% consensus/90% consensus/80% consensus/70% pid 1 [ COV 100.0% 100.0% 100.0 % 83.8% 100.0 % 78.6% 94.8% 24.2% 94.8% 24.2% 94.8% 25.5% 94.8% 25.5% 86.4% 21.1% 94.8% 25.5% 81 -MGLSDGEWOLVLNVWGKVEADLAGHGQEVLIGLFKTHPETLOKFDKFKNLKSEED -MGLSDGEWOLVLNIWGKVETDLAGHGQEVLIRLFKNHPETLDKFDKFKHLKTEDEMKGSEDLKKHGNTVLTALGGILKK -MGLSDGEWOLVLNAWGKVEADVAGHGQEVLIRLFTGHPETLEKFDKFKHLKTEAEMKASEDLKKHGNTVLTALGGILKK MGHFTEEDKATITSLWGKVNVEDA--GGETLGRLLVVYPWTORFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKH MGHFTEEDKATITSLWGKVNVEDA--GGETLGRLLVVYPWTORFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKH MVHFTAEEKAAITSTWKLVDVEDA--GAEALGRLLVVYPWTORFFDSFGNLSSSSAIMGNPKVKAHGKKVLTAFGDAVKN MVHFTPEEKCIISKOWGOVNIDET--GGEALGRLLVVYPWTORFFDNFGNLSSSSAIMGNPKVKAHGKKVLTSFGDAIKN MVHLSSEEKSAVTALWGKVNVEEV--GGEALGRLLVVYPWTORFFESFGDLSSAHAVMSNPKVKAHGKKVLAAFSEGLNH --MLTAEEKASVISLF- KGSEDLKKHGCTVLTALGTILKK ..hho.t-ht.l.t.a.... ..hho.t-ht.l.t.a... .hhhLhhsap.T.chf-pftpl.ottthhus.clKtHGppVL suhuthlpp ....hhhLhhsap.T.chF-pFtp.ottthhus.clKtHGppVL suhuthlpp .hthott-hth1hshwt.Vph-.s..GtEsLhtLhhsap..chF-pFtp potpthhus.clktHGppVL suhuth1kp .hthostEnth1hshwGpVps-.s..GtEsLhRLhssap..chFDpFts LpStsshhGs.clKtHGppVLTuhGsh1Kp -AKVLLVVYPWTORFFEHFGDLFSADAILGNPKVKGHGKKVLNSFSEGLKO 1 COV pid 100.0% 100.0% KGQHAAETOPLAQSHATKHKIPVKYLEFISEIIIEVLKKRHSGDF GADAOGAMSKALELFRNDIAAKYKELGFQG 100.0% 83.8% 100.0 % 78.6% 94.8% 24.2% 94.8% 24.2% 94.8% 25.5% 94.8% 25.5% 86.4% 21.1% 94.8% 25.5% ] 155 KGHHEAELKPLAQSHATKHKIPVKYLEFISDAIIQVLOSKHSGDFHADTEAAMKKALELFRNDIAAKYKELGFQG KGHHEAEVKHLAESHANKHKIPVKYLEFISDAIIHVLHAKHPSDFGADAQAAMSKALELFRNDMAAOYKVLGFHG LDDLKGTFAQLSELHCOKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTGVASALSSRYH- LDDLKGTFAQLSELHCOKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTAVASALSSRYH- VDDLKNTFAHLSELHCORLHVDPENFKLLGNVLVIVLAKYFGKEFTPOVOSAWOKLVAGVATALAHKYH- MONLKGAFAKLSELHCOKLHVDPENFKLLGNVLLIVLATHFGKEFTPEVQAAWQKLVSGVAIALAHKYH- LDDLKGAFASLSELHCOKLHVDPENFRLLGNVLVVVLARRFGGEFTPELOANFQKVVTGVANALAHRYH- LDNLKGTFAKLSELHCOKLHVDPENFRLLGNVL VVVL SHHFGKEFTPOVQAAYOKVVAGVANALAHKYH- hsphtstht.Lup.Hss+h+lssc.hchluph11.VLt.hast-FtsphpushpKh1thht.shutpy+. hsphtstht.Lup.Hss+h+lssc.hchluph11.VLt.hast-FtsphpushpKhlthht.shutpy+. hsphcutht.Lup.HssKh+lssc.hchluss11.VLth+aut-FsspsQuuhpKhlthhtsslut+v+. hsphcuphtpLUE-HssKh+lssc.hchluslllhVLtt+aut-Fss-SQAuhpKh1phhtsslAt+v+ 80

1 Mus 2 Canis 3 Bos 4 G-gamma 5 A-gamma 6 gamma 7 epsilon 8 fetal 9 beta consensus/100% consensus/90% consensus/80% consensus/70% 1 Mus 2 Canis 3 Bos 4 G-gamma 5 A-gamma 6 gamma 7 epsilon 8 fetal 9 beta consensus/100% consensus/90% consensus/80% consensus/70% pid 1 [ COV 100.0% 100.0% 100.0 % 83.8% 100.0 % 78.6% 94.8% 24.2% 94.8% 24.2% 94.8% 25.5% 94.8% 25.5% 86.4% 21.1% 94.8% 25.5% 81 -MGLSDGEWOLVLNVWGKVEADLAGHGQEVLIGLFKTHPETLOKFDKFKNLKSEED -MGLSDGEWOLVLNIWGKVETDLAGHGQEVLIRLFKNHPETLDKFDKFKHLKTEDEMKGSEDLKKHGNTVLTALGGILKK -MGLSDGEWOLVLNAWGKVEADVAGHGQEVLIRLFTGHPETLEKFDKFKHLKTEAEMKASEDLKKHGNTVLTALGGILKK MGHFTEEDKATITSLWGKVNVEDA--GGETLGRLLVVYPWTORFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKH MGHFTEEDKATITSLWGKVNVEDA--GGETLGRLLVVYPWTORFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKH MVHFTAEEKAAITSTWKLVDVEDA--GAEALGRLLVVYPWTORFFDSFGNLSSSSAIMGNPKVKAHGKKVLTAFGDAVKN MVHFTPEEKCIISKOWGOVNIDET--GGEALGRLLVVYPWTORFFDNFGNLSSSSAIMGNPKVKAHGKKVLTSFGDAIKN MVHLSSEEKSAVTALWGKVNVEEV--GGEALGRLLVVYPWTORFFESFGDLSSAHAVMSNPKVKAHGKKVLAAFSEGLNH --MLTAEEKASVISLF- KGSEDLKKHGCTVLTALGTILKK ..hho.t-ht.l.t.a.... ..hho.t-ht.l.t.a... .hhhLhhsap.T.chf-pftpl.ottthhus.clKtHGppVL suhuthlpp ....hhhLhhsap.T.chF-pFtp.ottthhus.clKtHGppVL suhuthlpp .hthott-hth1hshwt.Vph-.s..GtEsLhtLhhsap..chF-pFtp potpthhus.clktHGppVL suhuth1kp .hthostEnth1hshwGpVps-.s..GtEsLhRLhssap..chFDpFts LpStsshhGs.clKtHGppVLTuhGsh1Kp -AKVLLVVYPWTORFFEHFGDLFSADAILGNPKVKGHGKKVLNSFSEGLKO 1 COV pid 100.0% 100.0% KGQHAAETOPLAQSHATKHKIPVKYLEFISEIIIEVLKKRHSGDF GADAOGAMSKALELFRNDIAAKYKELGFQG 100.0% 83.8% 100.0 % 78.6% 94.8% 24.2% 94.8% 24.2% 94.8% 25.5% 94.8% 25.5% 86.4% 21.1% 94.8% 25.5% ] 155 KGHHEAELKPLAQSHATKHKIPVKYLEFISDAIIQVLOSKHSGDFHADTEAAMKKALELFRNDIAAKYKELGFQG KGHHEAEVKHLAESHANKHKIPVKYLEFISDAIIHVLHAKHPSDFGADAQAAMSKALELFRNDMAAOYKVLGFHG LDDLKGTFAQLSELHCOKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTGVASALSSRYH- LDDLKGTFAQLSELHCOKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTAVASALSSRYH- VDDLKNTFAHLSELHCORLHVDPENFKLLGNVLVIVLAKYFGKEFTPOVOSAWOKLVAGVATALAHKYH- MONLKGAFAKLSELHCOKLHVDPENFKLLGNVLLIVLATHFGKEFTPEVQAAWQKLVSGVAIALAHKYH- LDDLKGAFASLSELHCOKLHVDPENFRLLGNVLVVVLARRFGGEFTPELOANFQKVVTGVANALAHRYH- LDNLKGTFAKLSELHCOKLHVDPENFRLLGNVL VVVL SHHFGKEFTPOVQAAYOKVVAGVANALAHKYH- hsphtstht.Lup.Hss+h+lssc.hchluph11.VLt.hast-FtsphpushpKh1thht.shutpy+. hsphtstht.Lup.Hss+h+lssc.hchluph11.VLt.hast-FtsphpushpKhlthht.shutpy+. hsphcutht.Lup.HssKh+lssc.hchluss11.VLth+aut-FsspsQuuhpKhlthhtsslut+v+. hsphcuphtpLUE-HssKh+lssc.hchluslllhVLtt+aut-Fss-SQAuhpKh1phhtsslAt+v+ 80

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Identify the polar amino acids that are highly conserved (100% conserved), and list them in order of the sequence

1 Mus 2 Canis 3 Bos 4 G-gamma 5 A-gamma 6 gamma 7 epsilon 8 fetal 9 betal consensus/100% consensus/90% consensus/80% consensus/70% 1 Mus 2 Canis 3 Bos 4 G-gamma 5 A-gamma 6 gamma 7 epsilon. 8 fetal 9 beta consensus/100% consensus/90% consensus/80% consensus/70% pid 1 [ cov 100.0% 100.0% 100.0 % 83.8% 100.0% 78.6% 94.8% 24.2% 94.8% 24.2% 94.8% 25.5% 94.8% 25.5% 86.4% 21.1% 94.8% 25.5% MVHLSSEEKSAVTALWGKVNVEEV--GGEALGRLLVVYPWTORFFESFGDLSSAHAVMSNPKVKAHGKKVLAAFSEGLNH cov pid 100.0% 100.0% 100.0% 83.8% 100.0% 78.6% 94.8% 24.2% 94.8% 24.2% 94.8% 25.5% 94.8% 25.5% 86.4% 21.1% 94.8% 25.5% 81 -MGLSDGEWQLVLNVWGKVEADLAGHGQEVLIGLFKTHPETLDKFDKFKNLKSEEDMKGSEDLKKHGCTVLTALGTILKK -MGLSDGEWOLVLNIWGKVETDLAGHGQEVLIRLFKNHPETLDKFDKFKHLKTEDEMKGSEDLKKHGNTVLTALGGILKK -MGLSDGEWQLVLNAWGKVEADVAGHGQEVLIRLFTGHPETLEKFDKFKHLKTEAEMKASEDLKKHGNTVLTALGGILKK MGHFTEEDKATITSLWGKVNVEDA--GGETLGRLLVVYPWTORFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKH MGHFTEEDKATITSLWGKVNVEDA--GGETLGRLLVVYPWTORFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKH MVHFTAEEKAAITSTWKLVDVEDA--GAEALGRLLVVYPWTORFFDSFGNLSSSSAIMGNPKVKAHGKKVLTAFGDAVKN MVHFTPEEKCIISKOWGOVNIDET--GGEALGRLLVVYPWTORFFDNFGNLSSSSAIMGNPKVKAHGKKVLTSFGDAIKN --MLTAEEKASVISLF- ..hho.t-ht.l.t.a.. ..hho.t-ht.l.t.a.. -AKVLLVVYPWTORFFEHFGDLFSADAILGNPKVKGHGKKVLNSFSEGLKO ..hhhLhhsap.T.chF-pFtpL.ottthhus.clKtHGppVL suhuthlpp ..hhhLhhsap.T.chF-pFtpL.ottthhus.clKtHGppVLsuhuthlpp .hthott-hth1hshwt.Vph-.s..GtEsLhtLhhsap.T.chF-pFtpLpotpthhus.clKtHGppVL suhuth1kp .hthostEhth1hshWGpVps-.s..GtEsLhRLhssap.T.chFDpFtsLpStsshhGs.clktHGppVL TuhGsh1Kp KGQHAAEIOPLAQSHATKHKIPVKYLEFISEIIIEVLKKRHSGDFGADAQGAMSKALELFRNDIAAKYKELGFQG KGHHEAELKPLAQSHATKHKIPVKYLEFISDAIIQVLOSKHSGDFHADTEAAMKKALELFRNDIAAKYKELGFQG KGHHEAEVKHLAESHANKHKIPVKYLEFISDAIIHVLHAKHPSDFGADAQAAMSKALELFRNDMAAQYKVLGFHG LDDLKGTFAQLSELHCOKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTGVASALSSRYH- LDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTAVASALSSRYH- VDDLKNTFAHLSELHCDRLHVDPENFKLLGNVLVIVLAKYFGKEFTPOVOSAWOKLVAGVATALAHKYH- MDNLKGAFAKLSELHCOKLHVDPENFKLLGNVLLIVLATHFGKEFTPEVQAAWQKLVSGVAIALAHKYH- LDDLKGAFASLSELHCOKLHVDPENFRLLGNVLVVVLARRFGGEFTPELQANFQKVVTGVANALAHRYH LDNLKGTFAKLSELHCDKLHVDPENFRLLGNVLVVVLSHHFGKEFTPOVQAAYQKVVAGVANALAHKYH- hsphtstht.Lup.Hss+h+lssc.hchluphll.VLt.hast-FtsphpushpKhlthht.shutpy+. hsphtstht.Lup.Hss+h+lssc.hchluphll.VLt.hast-FtsphpushpKhlthht.shutpy+ hsphcutht.Lup. HssKh+lssc.hchluss11.VLth+aut-FsspsQuuhpKhlthhtsslut+Y+. hsphcuphtpLUE.HssKh+lssc.hchluslllhVLtt+aut-Fss-SQAuhpKh1phhtsslAt+Y+ 155 80
Transcribed Image Text:1 Mus 2 Canis 3 Bos 4 G-gamma 5 A-gamma 6 gamma 7 epsilon 8 fetal 9 betal consensus/100% consensus/90% consensus/80% consensus/70% 1 Mus 2 Canis 3 Bos 4 G-gamma 5 A-gamma 6 gamma 7 epsilon. 8 fetal 9 beta consensus/100% consensus/90% consensus/80% consensus/70% pid 1 [ cov 100.0% 100.0% 100.0 % 83.8% 100.0% 78.6% 94.8% 24.2% 94.8% 24.2% 94.8% 25.5% 94.8% 25.5% 86.4% 21.1% 94.8% 25.5% MVHLSSEEKSAVTALWGKVNVEEV--GGEALGRLLVVYPWTORFFESFGDLSSAHAVMSNPKVKAHGKKVLAAFSEGLNH cov pid 100.0% 100.0% 100.0% 83.8% 100.0% 78.6% 94.8% 24.2% 94.8% 24.2% 94.8% 25.5% 94.8% 25.5% 86.4% 21.1% 94.8% 25.5% 81 -MGLSDGEWQLVLNVWGKVEADLAGHGQEVLIGLFKTHPETLDKFDKFKNLKSEEDMKGSEDLKKHGCTVLTALGTILKK -MGLSDGEWOLVLNIWGKVETDLAGHGQEVLIRLFKNHPETLDKFDKFKHLKTEDEMKGSEDLKKHGNTVLTALGGILKK -MGLSDGEWQLVLNAWGKVEADVAGHGQEVLIRLFTGHPETLEKFDKFKHLKTEAEMKASEDLKKHGNTVLTALGGILKK MGHFTEEDKATITSLWGKVNVEDA--GGETLGRLLVVYPWTORFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKH MGHFTEEDKATITSLWGKVNVEDA--GGETLGRLLVVYPWTORFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKH MVHFTAEEKAAITSTWKLVDVEDA--GAEALGRLLVVYPWTORFFDSFGNLSSSSAIMGNPKVKAHGKKVLTAFGDAVKN MVHFTPEEKCIISKOWGOVNIDET--GGEALGRLLVVYPWTORFFDNFGNLSSSSAIMGNPKVKAHGKKVLTSFGDAIKN --MLTAEEKASVISLF- ..hho.t-ht.l.t.a.. ..hho.t-ht.l.t.a.. -AKVLLVVYPWTORFFEHFGDLFSADAILGNPKVKGHGKKVLNSFSEGLKO ..hhhLhhsap.T.chF-pFtpL.ottthhus.clKtHGppVL suhuthlpp ..hhhLhhsap.T.chF-pFtpL.ottthhus.clKtHGppVLsuhuthlpp .hthott-hth1hshwt.Vph-.s..GtEsLhtLhhsap.T.chF-pFtpLpotpthhus.clKtHGppVL suhuth1kp .hthostEhth1hshWGpVps-.s..GtEsLhRLhssap.T.chFDpFtsLpStsshhGs.clktHGppVL TuhGsh1Kp KGQHAAEIOPLAQSHATKHKIPVKYLEFISEIIIEVLKKRHSGDFGADAQGAMSKALELFRNDIAAKYKELGFQG KGHHEAELKPLAQSHATKHKIPVKYLEFISDAIIQVLOSKHSGDFHADTEAAMKKALELFRNDIAAKYKELGFQG KGHHEAEVKHLAESHANKHKIPVKYLEFISDAIIHVLHAKHPSDFGADAQAAMSKALELFRNDMAAQYKVLGFHG LDDLKGTFAQLSELHCOKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTGVASALSSRYH- LDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTAVASALSSRYH- VDDLKNTFAHLSELHCDRLHVDPENFKLLGNVLVIVLAKYFGKEFTPOVOSAWOKLVAGVATALAHKYH- MDNLKGAFAKLSELHCOKLHVDPENFKLLGNVLLIVLATHFGKEFTPEVQAAWQKLVSGVAIALAHKYH- LDDLKGAFASLSELHCOKLHVDPENFRLLGNVLVVVLARRFGGEFTPELQANFQKVVTGVANALAHRYH LDNLKGTFAKLSELHCDKLHVDPENFRLLGNVLVVVLSHHFGKEFTPOVQAAYQKVVAGVANALAHKYH- hsphtstht.Lup.Hss+h+lssc.hchluphll.VLt.hast-FtsphpushpKhlthht.shutpy+. hsphtstht.Lup.Hss+h+lssc.hchluphll.VLt.hast-FtsphpushpKhlthht.shutpy+ hsphcutht.Lup. HssKh+lssc.hchluss11.VLth+aut-FsspsQuuhpKhlthhtsslut+Y+. hsphcuphtpLUE.HssKh+lssc.hchluslllhVLtt+aut-Fss-SQAuhpKh1phhtsslAt+Y+ 155 80
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