The X Factor

on X-Factor (“One Direction Biography” para. 1). These boys made it on to Season 7 of X-Factor (“One Direction Biography” para. 1). There were thousands of boy lined up for auditions on X-Factor and did not make it (“One Direction Biography” para. 2). Niall Horan, Zayn Malik, Harry Styles, Liam Payne, and Louis Tomlinson were boys that were lucky enough to make it through (“One Direction Biography” para. 2). Louis Tomlinson’s auditioning song for X- Factor was “Hey There Delilah” (“X-Factor para

circulatory system, and carries with it the essential ability to clot, or become thicker, which prevents excessive bleeding for a laceration. This clotting is caused by proteins in the blood, specifically the proteins known as coagulation factor VIII and coagulation factor IX, which work with tiny particles called platelets to form the clot. However, in a rare genetic disorder known as Hemophilia, these clotting proteins are either missing from the blood or found in lower does than in the blood of the

Hemophilia A and B are x-linked disorders that cause bleeding due to the absence of a coagulation factor, which arise from mutations in the VIII (FVIII) and IX (FIX) factor genes1. Recent advances in the field of gene therapy have unveiled the use of adeno-associated vectors (AAV) and adenovirus vectors (Ad) to increase the levels of expression of the VIII and IX factors, counteracting the effects of the mutation 1. Gene transfer methods of the coagulation factor IX using AAV has resulted in dogs

JamesFoley, a music journalist, describes this influence as follows: “Does [ The X Factor ] impact on thesigning and release schedules of other labels? Of course it does. They will do anything to avoid being up against JLS and Alexandra Burke and Leona Lewis [all previous The X Factor contestants], because they know they have automatic access to a promotions platform that other labels don't have” (Addley, par. 10).To reiterate, talent

Hemophilia A is an X-linked disorder caused by a deficient or defective clotting factor VIII (FVIII) protein, and characterized by spontaneous or traumatic bleeding into joints and muscles [Ragni]. It causes afflicted individuals to not be able to coagulate their blood very efficiently or at all when getting an injury in which blood is exposed either internally or externally. This disease can be very dangerous and fatal because major blood loss can occur if the patient has not received treatment

is caused by a deficiency of factor VIII (Carson-DeWitt, 2014). This deficiency can vary in severity. This is why each case of Hemophilia varies in each case. Most people have severe Hemophilia which means that the factor is functioning at a hundredth of what it should be.

Both result in very similar symptoms, however, they are caused by different mutations of genes on the X chromosome. The way in which the disorder is inherited is known as an “X-linked recessive pattern.” Since males only have one X chromosome, one gene mutation is all that is needed in order to obtain hemophilia. On the other hand, females have two X chromosomes meaning that two mutations (on on each X chromosome) are required to inherit hemophilia. For that reason, it’s far more unlikely for females

comes from two Greek words: haima - meaning blood and philia meaning to love. In order for the blood to clot properly, the plasma proteins also called factors need to be present in the blood. When the body forms antibodies to the clotting factors in the blood, it will stop the clotting factors from working. There are 13 types of clotting factors and they involve platelets to help the blood coagulate. Platelets also known as thrombocytes are small blood cells that form in your bone marrow to prevent

hemophilia, and they are hemophilia A and hemophilia B. Hemophilia A is also called classic hemophilia, and is caused by a mutated or missing factor VIII, which is a clotting protein. Hemophilia B is sometimes called Christmas disease, because the disorder was first reported in a patient with the last name Christmas. Hemophilia B is caused by a mutated or missing factor XI, which is also a clotting protein. Although it wasn’t named yet, hemophilia was recognized in the 2nd century AD, in a collection

clothing factor VIII. Hemophilia A is also known as the ‘Classic Hemophilia.’ According to the CDC, hemophilia will occur in approximately 1 in 5,000 live births. It is called classic hemophilia due to the fact that this hemophilia is four times more common as hemophilia B. This disorder is mainly a hereditary bleeding disorder which is caused by an inherited X linked recessive trait. Some acquired forms do exist as well, largely in older patients, due to autoantibodies directed against factor VIII.