Which is not a Limit test in the Sodium Chloride drug substance/raw material monograph? (Note: NaCl is used as a drug to counter hypotension (low blood pressure), and as a raw material in saline solution.)
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Which is not a Limit test in the Sodium Chloride drug substance/raw material monograph?
(Note: NaCl is used as a drug to counter hypotension (low blood pressure), and as a raw material in saline solution.)
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- What is the minimum volume of dissolution media required to provide sink condition in dissolution test of a tablet dosage form (its weight: 1350 mg; dose strength: 1000 mg) regarding the following conditions? The molecular weight of an active drug substance is 500 Da; the dissolution media is water and the solubility of active drug substance in water is 10 mg/Ml (4. SLAYT) 500 ml 1000 ml 1350 ml 100 ml 135 mlThe doctor ordered Oxacillin 650mg every 6 hours. The instructions on the 2gm vial states to reconstitute with powder with 11.5ml of sterile water for injection, yielding 220mg/1.5ml. How many ml will you administer? using dimensional analysis and show workA nurse wants to know the what volume of Water for Injection, BP to be added to a vial containing 500mg doxorubicin to produce an injection with a concentration of 2.5 mg/mL. The displacement volume of doxorubicin is 0.3 mL/10 mg.
- A prescription order calls for 1.25 g of vancomycin in 500 mL of NS (0.9%/100mL). After reconstitution vancomycin injection is available in a strength of 50 mg/mL. How many mL of vancomycin injection should be drawn up to prepare this prescription?A physician orders a 375 mg/m2 dose of Rituxan in 500 mL NS for a patient with a BSA of . Rituxan is available in 10 mL vials in a concentration of 10 mg/mL. How many mL will be added to the IV bag?Streptomycin sulfate 400 mg IM daily is ordered for a child weighing 77lbs. The recommended dosage is 20-40 mg/kg/day once daily. A 1 gram vial of streptomycin sulfate is available in powdered form with the following instructions: Dilution with 1.8 mL of sterile water will yield 400mg per mL. If safe, how many mLs will you give?
- Furosemide is packaged as 10 mg/mL. A pharmacy technician must make a preparation totaling 25 mL of 2 mg/mL concentration. How much drug and how much diluent are used? (Textbook says use %w/v to calculate and the answer key says 5 mL concentrate; 20 mL diluent. I'm looking for how to set up and solve this problem.)Both the physical properties of the API and the excipients are essential to ensure that the formulation is physically stable and suitable for administration to patients. Discuss the general formulation considerations. The instability of emulsions may be either reversible or irreversible. Cracking indicates the extensive coalescence of the internal phase, consequently, leads to the separation of the emulsion into two distinct layers. How the cracking is occurring in the emulsions? If an emulsion has cracked will it be recovered. If yes/no discuss the phenomena. Discuss the lyophilization and appraise its importance in the pharmaceutical industry with suitable examplesA 250 mL IV solution contains 25,000 units of heparin. The desired dosage is 8 units/kg/hr. The patient weighs 220 Ibs. The drop factor is 60 gtts/mL.. How many units of heparin are in 5 mL of solution? (Hint: how many are in 1 mL? Now, how many are in 5?)
- a) What are the methods used for cholesterol determination? Explain the basis of the method you used in your experiment by writing.b) In the experiment conducted for the determination of cholesterol, the function of the calibration curve obtained using standard cholesterol solutions of 25-400mg/dl was determined as y= 0.0009x.Since the absorbance of the serum sample was determined as 0.28, how many mg/L is the amount of cholesterol in the samplethis patient suffers from Parkinson’s disease and has been admitted with nausea, confusion and a fall. The most recent blood results and observations are shown below:Sodium – 136mmol/LPotassium – 4.0mmol/LCreatinine – 110micromol/LCRP – 25mg/LBp – 110/78mmHgWhich tests would you expect to be conducted in this patient? List below up to 4 patient issues that you have identified, think about who you would speak to about each of these: What are the typical issues associated with the administration of medication for Parkinson’s disease.A medication order for a patient weighing 70 Kg is 0.75 mg of ampicillin per Kg BW to be added to 900 mL of 5% dextrose injection. The ampicillin injection is to be obtained in 2.5 mg/mL ampule. What is the total volume in mL of the IV admixture? Choose the best answer.