What would most likely occur to nuclear-cytoplasmic shuttling if the intrinsic GTPase activity of RAN was slowed down by 50%? All of the answers are likely O None of the answers are likely RAN would not bind to importin beta and protein cargo in the nucleus would not release Importin beta would not release from RAN in the cytoplasm and nuclear import would slow down O RAN would not bind exportin and proteins would accumulate in the nucleus

What would most likely occur to nuclear-cytoplasmic shuttling if the intrinsic GTPase activity of RAN was slowed down by 50%? All of the answers are likely O None of the answers are likely RAN would not bind to importin beta and protein cargo in the nucleus would not release Importin beta would not release from RAN in the cytoplasm and nuclear import would slow down O RAN would not bind exportin and proteins would accumulate in the nucleus

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter9: Cell Communication

Section: Chapter Questions

Problem 3ITD

See similar textbooks

Similar questions

Which describes an enzymatic activity/biochemical function of importin-beta? facilitate release of nuclear proteins after transport through the nuclear pore complex interact with/bind to nuclear localization sequences INLSS) interact with/bind to importin-alpha hydrolyze GTP to GDP + Pi
What would happen to nuclear transport if you removed all of the Ran-GAP? For a while nuclear import receptors will still deliver cargo to the inside of the nucleus Nuclear import receptors will be loaded with RanGTP and will gradually stop binding to the proteins with NLS signals Nuclear export receptors will no longer deliver their cargo to the outside of the membrane and will probably shuttle in and out of the nucleus full of cargo Ran-GDP will no longer be made All of the above
Cytokine receptors and tyrosine kinase receptors are similar in all of the following ways EXCEPT one. Which one is the exception? O They are both down-regulated by lysosomal degradation They both involve receptor exoplasmic domain dimerization They both result in an effector protein entering the nucleus O They both involve cytosolic domain phosphorylation
What is the role of the Ran-GAP protein in nuclear transport? Ran-GAP converts RanGTP to RanGDP Ran-GAP is a receptor on the nuclear membrane Ran-GAP is not directly involved in nuclear transport, it is a transcription factor Ran-GAP shuttles between mitochondria and the nucleus Ran-GAP converts RanGDP to RanGTP
TGF-B Receptor I (RI) phosphorylation of Smad2/3 does all of the following EXCEPT: activate Smad2/3 binding to the Co-Smad Smad4 dissociate intramolecular binding of Smad2/3 MH1 and MH2 domains. RI phosphorylation of Smad2/3 does all of these things. release Smad2/3 from the nucleus into the cytoplasm unmask the Smad2/3 nuclear localization signal (NLS).
Nucleation of straight, single line microfilaments is mediated by which of the following? Rho GTPase and Formin Rho GTPase and Arp 2/3 Cdc42 GTPase and Arp2/3 OCdc42 GTPase and Formin 14 < Previous
What is the role of the Ran-GEF protein in nuclear transport? Ran-GEF converts RanGTP to RanGDP Ran-GEF binds Ran-GAP on inside of nucleus to speed up transport Ran-GEF converts RanGDP to RanGTP Ran-GEF maintains the RanGTP concentration on the inside of the nucleus low Ran-GEF binds directly to the nuclear pore to facilitate transport
Some drugs can prevent the formation of new lysosomes. However, a cell would continue to make hydrolytic enzymes from the DNA still contained in the cell. Where would you most likely find these enzymes after the drug treatment? O Golgi Complex O Smooth Endoplasmic Reticulum O Nucleus O Mitochondrion Strikingly different signaling systems can operate in similar ways. For example, ethylene gas released by ripening fruits diffuses through the air from plant to
# 3 You've engineered a mutant cell where the FADD adapter was truncated. The mutant FADD only contains the Death Domain, and lacks the Death Effector Domain. What is the most likely phenotypic outcome for this mutant cell when presented with the Fas ligand? 20 E O The Fas/FasL oligomer is formed, but apoptosis is blocked O The Fas/FasL oligomer is formed, and apoptosis is hyperactivated O The Fas/FasL oligomer is not formed, and apoptosis is blocked O The Fas/FasL oligomer is not formed, but apoptosis is hyperactivated F3 $ 4 DOD 000 R F4 % 5 F5 T BARAT 6 tv @ MacBook Air F6 Y & 7 F7 U * ➤11 8 F8 · 9 F9
The small, monomeric protein Rho has acquired a mutation by which it is constitutively activated and evenly distributed along with the cytoplasmic leaflet of the plasma membrane. Describe the effects this would have on cell crawling. A complete answer will include a description of normal Rho distribution and activation, an explanation of Rho function in cell crawling, and a thoughtful argument for an overall effect of the mutation on cell crawling that is based on the specific roles of Rho.
DNA damage can suppress the activity of the following cyclin-dependent kinases EXCEPT G1/S-Cdk S-Cdk M-Cdk G1-Cdk Which phenomenon allows the formation of double and triple bonds between carbon atoms? * Reduction Radioactivity Oxidation Hybridization If an agent that disrupts microtubules activity was added to cells at M phase, the cells will ble expected to get arrested at Anaphase O Metaphase O Prophase Telophase O 0 O
Which statement about the M6P receptor is true/accurate? Answers: It is involved in retrieval of ER resident proteins from the Golgi and transport back to the ER. Due to no difference in pH in the lumen of each, it has the same affinity for M6P in the Golgi as in the endosome. Due to a slight difference in pH in the lumen of each, it has a high affinity for M6P in the Golgi and a low affinity for M6P in the endosome. Due to a slight difference in pH in the lumen of each, it has a low affinity for M6P in the Golgi and a high affinity for M6P in the endosome.