What would be the effect on the activity of phosphofructokinase of the mutation of Asp103 to the unusual amino acid shown below? Explain in terms of actual structures of the side chains of Asp and this unusual amino acid.
Q: Complete the Haworth projection of B-D-fructose. The anomeric carbon is shown. C H Answer Bank OH…
A:
Q: The food industry often uses catalytic hydrogenation to convert double bonds in the fatty acids of…
A: Note:- Sorry, since you have posted multiple. questions, we will be solving the first one for you as…
Q: Construct the mechanism of a serine-protease with a catalytic triad.
A: A serine protease is an enzyme that cleaves peptide bonds in proteins and peptides. It possesses a…
Q: What is the net charge of cysteine in an aqueous solution at pH 9? Carboxyl group pKa = 1.92; Amino…
A: Cysteine is a polar but uncharged amino acid with thiol side group. The cysteine side group is…
Q: Put these three molecules in the order of most oxidized to least oxidized. нн нс-с-н нн H > > 0=…
A: In chemistry, the concept of oxidation state plays a crucial role in assessing the degree of…
Q: The ESI-MS spectrum in positive ionization mode for lysozyme is obtained. a. What is the molecular…
A: The y-axis of the ESI-MS spectrum reflects relative abundance and the x-axis the m/z (mass charge)…
Q: 19. Draw all 20 of the genetically encoded amino acids at (a) pH = 1; (b) pH = 1; (c) pH = 12.…
A: Amino acids are organic compounds that form the building blocks of proteins in cells. The structure…
Q: The toxic effect of Na+ ions can be avoided in some plant species by storing them in membrane-bound…
A: One kind of active transport that moves Na+ ions through a membrane is the Na+/H+ antiport…
Q: The fungus Aspergillus giganteus degrades wood using the ribonuclease a-Sarcin. Of the molecules…
A: The ribonuclease α-Sarcin is used by the fungus Aspergillus giganteus to decompose wood. By…
Q: Describe the structure and function of the bacterial cell wall, and explain it importance as a…
A: (1) Structure of bacterial cell wall - The bacterial cell wall is made up of peptidoglycan or…
Q: Why is having flexible and unstructured regions of a protein important for the function of the…
A: Proteins are polypeptide structures made up of one or more extended chains of residues from the…
Q: O A) H₂N H3N² B) D) H3N H₂N -CH-COO™ CH₂ CH₂ S CH3 -CH-COO CH₂ CH₂ CIO -o -CH-COO CH₂ OH -CH-COO CH₂…
A: Organic substances known as amino acids are the foundation of proteins and are important to many…
Q: 1. (a) By binding one L-tryptophan molecule/monomer, the trp repressor binds to DNA to sup- press…
A: An atom's or molecule's electrostatic charge, which can be either positive or negative depending on…
Q: protein Insulin (also see Fig 14.24) Ferritin Myoglobin Hemoglobin Ribonuclease a-keratin Collagen…
A: Insulin is a protein hormone, and its structure is quite fascinating. It's made up of two chains of…
Q: DNA sometimes has chemical groups attached, called methyl groups, that affect gene expression.…
A: Methyl groups on DNA have a significant role in epigenetics and gene regulation and have a strong…
Q: An enzyme inhibitor that decreases the apparent KM and reduces the Vmax can be classified as an…
A: Enzymes are high molecular weight proteins that catalyse biochemical reactions. They contain an…
Q: Many enzyme mechanisms involve transferring protons. Sidechains of an enzyme can act as catalytic…
A: Described in the image is the reaction catalysed by triosephosphate isomerase. In an electron…
Q: Write out the mechanism of TIM-catalyzed reaction in the direction it goes in glycolysis. Show…
A: In order to produce energy, glucose or other carbohydrates must be broken down. This process is…
Q: What are the molecular weights of the protein X polypeptides? (pick 1 only) - 50 kDa each - 60 kDa…
A: Native PAGE is a technique that uses non-denaturing gels (in the absence of SDS or any denaturing…
Q: The active form of insulin contains No disulfide bonds Intra-chain disulfide bonds Inter-chain…
A: Insulin is a peptide hormone secreted by beta cells of pancreatic islets of Langerhans that…
Q: A diploid organism with a 45,000-kb haploid genome contains 21% G residues. Calculate the number of…
A: According to Chargaff's rules, DNA from each cell of any organism should contain a 1:1 ratio (base…
Q: For the reaction A + B = C + D, assume that the standard change in free energy has a positive value.…
A: Consider the following general reaction:aA + bB ⇌ cC + dDAt equilibrium (steady state), the…
Q: Disulfide bridges can be formed by structures. O Methionine; tertiary and quaternary OCysteine;…
A: Cysteine is an amino acid that contains a sulfur atom in its side chain (R group). This sulfur atom…
Q: Given the data for Chymosin shown below: What are the catalytic constants (i.e. Km and Vmax) for…
A: Km is the catalytic constant which is equal to substrate concentration at half of maximal…
Q: write the one letter code for oligopeptide ser-cys-ille-glu-Asn-cys-glu and calculate the total…
A: Before calculating the total charge on the peptide, we need to be thorough with the principle behind…
Q: 3. Aspartate aminotransferase (AspAT) catalyzes the following reaction: COO™ C=O CH₂ COO…
A: Km is sometimes thoughtlessly used as an indicator of affinity of an enzyme for its substrate. But,…
Q: Each peak on the tandem mass spectrogram represents a product ion with a +1 charge. Use the…
A: Mass spectrometry is an analytical gel-free proteomics method used for identification of proteins,…
Q: the half life of metformin ( Glucophage) is 17.6 hours. What is the rate of decay?
A: A substance's half-life is the amount of time it requires for half of it to degrade or change into a…
Q: Calculate the equilibrium fraction of GAP from the above, at 37 ∘C?
A: The standard change in free energy is related to equilibrium constant by the equation Keq=…
Q: A gel filtration column was calibrated by measuring elution volumes for two proteins of known mass:…
A: The established amounts of the elution volumes for the two proteins with determined masses can be…
Q: Diisopropylphosphofluoridate (DIPF) inactivates chymotrypsin by covalently modifying serine 195.…
A: Diisopropylphosphofluoridate (DIPF) is an irreversible inhibitor of chymotrypsin. It forms a…
Q: Amino acids with ionizable side chains are found in all groups except: negatively-charged…
A: There are four classes of biological macromolecules: proteins, nucleic acids, lipids,…
Q: The molecule below is found in 0 ORNA. HO Osteroids. Oprotein. Ostarch. ODNA. .0 N OH OH NH 0
A: From the structure you can see there is a pentose sugar along with nitrogenous base.. This kind of…
Q: Describe two conditions when it is more advantageous to use carbohydrates as a metabolic fuel rather…
A: Carbohydrates are organic molecules that consist of carbon, hydrogen, and oxygen atoms in a ratio of…
Q: Mary Jo prepared a series of diluted samples by taking 1 mL of sample and adding it to 4 mLs of…
A: Here, Mary Jo is undertaking serial dilution (i.e. a series of consecutive dilutions) comprising of…
Q: Draw the structure of the products formed when Arabinose shown above undergoes the following…
A: Chemically a carbohydrate is polyhydroxy aldehyde or ketone. Based on the size, carbohydrate can be…
Q: Determine whether each of the carbohydrates is a monosaccharide, disaccharide, or polysaccharide.
A: Carbohydrates are biomolecules that comprise carbon, hydrogen and oxygen atoms. The hydrogen-oxygen…
Q: For the reaction glutamate (aq) + oxaloacetate2- (aq) a-ketoglutarate²- (aq) + aspartate- (aq) the…
A: When temperature and pressure are held constant, the amount of work that can be done in a…
Q: EP 1: Enzyme(E)+Substrate(S)=Enzyme-Substrate Complex (ES) FAST EP 2: Enzyme-Substrate Complex(ES)…
A: Enzyme catalyzed reaction occurs rapidly because it decreases activation energy hence causes the…
Q: Decide whether each of the following statements is true about pyruvate decarboxylase. It…
A: It is an enzyme which catalyses the reaction of decarboxylation of pyruvic acid in to acetaldehyde.…
Q: The graph shows the oxygen-binding curves for myoglobin and hemoglobin. Label the graph and answer…
A: Fractional Saturation (θ) is the fraction of protein molecules saturated with ligands. (since it is…
Q: In a reaction system, the concentrations of Enzyme-Substrate complex [ES], free enzyme [E] and free…
A: An indicator of the degree to which two molecules are bound together, the equilibrium association…
Q: Which one of these molecules would not be in a membrane? HC-0 НО HC-0 HC-0 image A D Galactose is a…
A: The most prevalent lipid molecules found in plasma membranes, commonly referred to as cell…
Q: 1: QAMGRAGDLKYLGLHSV Peptide 2: ALMALFMVMALVLVSVLFIA Peptide 3: MVEDLLKQIARYLISE (a) Circle all of…
A: We are authorized to provide three sub parts at a time; since you have not mentioned which part, we…
Q: The amino acid shown below has an ionizable side chain with a pka of 4. When this amino acid is in a…
A: There are four types of biological macromolecules- proteins, nucleic acids, lipids and…
Q: how do telomeres protect against replicative shortening
A: Telomeres occur as repetitive regions found towards the end of a chromosome. Telomeres occur in a…
Q: The table below lists experimental conditions that can be applied to a reaction catalyzed by a…
A: For a one-substrate enzyme-catalyzed reaction, the Michaelis-Menton equation shows the quantitative…
Q: beach in California and caught cute little crab and wanted to take it home. Knowing that it wouldn't…
A: Strength of a solution = mass of solute in grams / volume of solute in litresHere the solute is…
Q: Consider the following isomerization reactions of some simple sugars and values for their standard…
A: Details
Q: Part C If, in addition to the constraints on glucose concentration listed previously, we have in the…
A: Pi + Glucose -> Glucose-6-Phosphate + H2OFor the above reaction, ΔG°’ = + 13.8 kJ/mol and…
What would be the effect on the activity of phosphofructokinase of the mutation of Asp103 to the unusual amino acid shown below? Explain in terms of actual structures of the side chains of Asp and this unusual amino acid.
Step by step
Solved in 3 steps with 1 images
- Difference between polypeptide and proteinI-D-E-L-Y-S-Q-V-C-S-H-L-D-T-V-R The amino acid sequence above forms an alpha helix. Place the amino acids on the wheel given below. L1 represents Leu.b. In superhelical proteins, such as collagen, several polypeptide helices are intertwined. What is the function of this superhelical twisting?