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- Drug X 100mg is administered as an intramuscular injection and has the following pharmacokinetic parameters:t1/2 = 8hrska = 1.5h−1 V= 10lF = 65%What will be the concentration at 12hrs after the dose is administered?The normal concentration of Ca2+ in blood is 5.0 mEq>L. How many milligrams of Ca2+ are in 1.00 L of blood?RMI are the following except?
- Michael (4 year old; 19 kg) has been admitted to hospital due to a paracetamol overdose. The antidote for a paracetamol overdose is acetycysteine at a dose of 50 mg/kg. The ampoules contain 2 g in 10 mL. The acetycysteine is infused over 4 hours in 500 mL of 5% dextrose. Calculate the volume (in mLs to 1 d.p.) of acetylcysteine to be drawn from the ampoules for the infusion.Plasma or serum LDL-Cholesterol (LDL-C) can be calculated by determining concentrations of total plasma (serum cholesterol (T-C), HDL-Cholesterol (HDL-C) and total plasma (serum) triglycerides(TG) using Friedewald equation: LDL-C = (T-C) - (HDL-C) - TG/5. What is the scientific basis for this equation? What are the limitations of this equation?Creatinine, C4H7N3O, is a by-product of muscle metabolism, and creatinine levels in the body are known to be a fairly reliable indicator of kidney function. The normal level of creatinine in the blood for adults is approximately 1.0 mg per deciliter (dL) of blood. If the density of blood is 1.025 g/mL, calculate the molarity of a normal creatinine level in a 10.0 mL blood sample.
- Sarah who weighs 67 kg is to receive acetylcysteine at a dose of 50 mg/kg infused over 4 hours for paracetamol overdose. The required volume of concentrated acetylcysteine solution (200 mg/mL) has been added to 500 mL of 5% glucose solution. What is the concentration of the solution to be infused (mg/mL)? (Answer to 1 decimal place.) Answer: 16.75 mg xThe concentration of glucose in blood is approximately 90 mg/100 mL. What is the mass/volume percent concentration of glucose? What is the molarity of glucose?Identify the predominant intermolecular forces in each of the given substances.
- a drug that will be administered as a 500mg oral solution has the following average pharmacokinetics parameters Ka= 1hr, Cl= 10l/he, V= 100ml, F= 0.5 what concentration would you expect 4 hr after the doseAnswer the following step by step A) If Dalmane is available as 15 mg capsules, what dosage is given with 2 capsules? B) Using 0.5 mg/kg of body weight for atropine by aerosol, what dose is needed for a 75-kg man? C) If Tempra is available as 120 mg/ 5 ml, how much dose is there in one-half teaspoon?Theoretically, the pI of myoglobin is 7.2. In phosphate buffer pH 6.0, what is the overall charge of myoglobin? How would it interact with CM Sepharose?