The quantitative differences in biological activity between the two enantiomers of a compound are sometimes quite large. For example, the D isomer of the drug isoproterenol, used to treat mild asthma, is 50 to 80 times more effective as a bronchodilator than the L isomer. Identify whether each of the indicated atoms in isoproterenol is a chiral center or achiral. chiral center OH ST HO H HO achiral CH₂ Isoproterenol H H chiral center -N-C-CH₂ CH 3 achiral

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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The quantitative differences in biological activity between the two enantiomers of a compound are sometimes quite large. For
example, the D isomer of the drug isoproterenol, used to treat mild asthma, is 50 to 80 times more effective as a bronchodilator
than the L isomer.
Identify whether each of the indicated atoms in isoproterenol is a chiral center or achiral.
HO
HO
chiral center
OH
C.
H
achiral
CH₂
Isoproterenol
H H
H—
- N
с
CH 3
achiral
chiral center
CH 3
Transcribed Image Text:The quantitative differences in biological activity between the two enantiomers of a compound are sometimes quite large. For example, the D isomer of the drug isoproterenol, used to treat mild asthma, is 50 to 80 times more effective as a bronchodilator than the L isomer. Identify whether each of the indicated atoms in isoproterenol is a chiral center or achiral. HO HO chiral center OH C. H achiral CH₂ Isoproterenol H H H— - N с CH 3 achiral chiral center CH 3
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