The four drugs A, B, C and D have the same IC50 values. Which of them has the highest efficacy? 100 H 50 % Response EC 50 A B C D ***************
The four drugs A, B, C and D have the same IC50 values. Which of them has the highest efficacy? 100 H 50 % Response EC 50 A B C D ***************
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Question
![QUESTION 7
The four drugs A, B, C and D have the same IC50 values. Which of them has the highest efficacy?
A
B
100
% Response
50
0
0.1
EC 50
A
B
C
D
1.0
10
100
[Drug] (nM/L) (semilog scale)](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fca0f63c5-9399-4a84-b7ec-fd5c52d6b740%2F91aff303-afff-4d07-9579-906b18511d01%2Fsqoims_processed.png&w=3840&q=75)
Transcribed Image Text:QUESTION 7
The four drugs A, B, C and D have the same IC50 values. Which of them has the highest efficacy?
A
B
100
% Response
50
0
0.1
EC 50
A
B
C
D
1.0
10
100
[Drug] (nM/L) (semilog scale)
Expert Solution
Introduction
Drugs are substances that can alter the body and mind, and are often used illegally to create a sense of pleasure or euphoria. They can have dangerous effects such as addiction, physical and mental health problems, and even death.
An IC50 curve is a graph that plots the concentration of a drug or other compound against its effect on a particular system. The IC50 value is the concentration at which the compound has a 50% effect on the system. The IC50 curve is used to determine the potency of a compound and may be used to compare different compounds.
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