decrease in*The following reaction occurs during the glycolysis pathway:glucose-6-phosphatea)b)AG°¹fructose-6-phosphate+0.4 kcal/molDetermine the value for the equilibrium constant in a mammalwhose body temperature is 37°C.In red blood cells, normal observed cellular concentrationsinclude 83 μM glucose-6-phosphate, and 14 μM fructose-6-phosphate. Under these conditions, is this reaction atequilibrium? If not, will it favor formation of morefructose-6-phosphate or more glucose-6-phosphate?What structural feature do NAD+ NADP+ and FAD have in common?

In a general reaction such as: aA + bB ⇌ cC + dD At equilibrium (steady state), the concentration of…

Answered: *The following reaction occurs during…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Similar questions

Intracellular concentrations in resting muscle are as follows: fructose- 6-phosphate, 1.0 mM; fructose-1,6-bisphosphate, 10 mM; AMP, 0.1 mM; ADP, 0.5 mM; ATP, 5 mM; and P, 10 mM. Is the phosphofructokinase reac- tion in muscle more or less exergonic than under standard conditions? By how much?
Calculate glucose concentration. Na (sodium) and glucose secondary active transport. Na transport (which drive glucose import) G=R*T*In(Na in/ Na out)+Z*F*Y(psi symbol) Na in=14mM Na out=145MM Z=+1 F=96.5 KJ/V*mol Y(psi)=-0.05V What is the glucose in and out concentration? Please be very through when explaining this calculation. (I am stuck at why the energy sign changes from negative to positive when using the calculated energy from sodium to glucose)
While fatty acids longer than 20 carbons are rarely found in foods, lignoceric acid (24:0) is found in a variety of tree nuts. Answer the following based on the conversion of a molecule of lignoceric acid to 8-hydroxybutyrate. (a) What are the 8-oxidation products and how many ATP are required during activation for one molecule of lignoceric acid? (b) Given the following, how many molecules of 8-hydroxybutyrate can be produced? CoA 2 2 CoA NADH NAD+ H+ OH ẞ-hydroxybutyrate (c) Based on the total NADH and FADH2 available after converting lignoceric acid into 8-hydroxybutyrate, what is the maximum yield of ATP that can be produced in the liver? Don't forget to include any ATP required for activation steps.
Intracellular concentrations in resting muscle are as follows: fructose6-phosphate, 1.0 mM; fructose-1,6-bisphosphate, 10 mM; AMP, 0.1 mM;ADP, 0.5 mM; ATP, 5 mM; and Pi, 10 mM. Is the phosphofructokinasereaction in muscle more or less exergonic than under standard conditions?By how much?
Intramitochondrial ATP concentrations are about 5 mM, and phosphate concentration is about 10 mM. If ADP is five times more abundant than AMP,calculate the molar concentrations of ADP and AMP at an energy charge of 0.85. Calculate ∆G for ATP hydrolysis at 37 °C under these conditions.The energy charge is the concentration of ATP plus half the concentration of ADP divided by the total adenine nucleotide concentration.
is this stement false? Intracellular concentrations in resting muscle are as follows: Fructose-6-phosphate (1.0 mM)Fructose-(1-6)-bisphosphate (10.0 mM)AMP (0.1 mM)ADP (0.5 mM)ATP (5.0 mM)Pi (10.0 mM)Under the above conditions the Phosphofructokinase reaction in muscle is more exergonic than under standard conditions.
Consider the following equilibrium at 25ºC :Glucose-1-Phosphate Glucose-6-PhophateUsing the equilibrium concentrations of [Glucose-1-Phosphate] = 0.35 M and [Glucose-6-Phosphate] = 1.65 M, calculate BOTH K′eqand Gº′ for this reaction. Is this reaction exergonicor endergonic? R = 8.314 J/K·mol
Calculate delta G of glucose transport into the cell if the concentration of clugoce is 1mM inside the cell and 100uM outside. R=2cal/mol*K and T=300K
Isomaltose (an isomer of maltose), one of the degradation products of starch is further hydrolyzed into its monosaccharide components prior to its intestinal absorption and entry into the glycolysis. Calculate the no. of ATP molecules produced from the digestion and complete oxidation of 1 molecule of isomaltose considering the glycerol-3-phosphate shuttle. Answer the ff.: a) Total no. of glucose molecules entering glycolysis b) Total no. of pyruvate mols. produced at the end of glycolysis c) Total no. of mitochondrial NADH produced after pyruvate is acted upon by pyruvate dehydrogenase complex d) Total no. of CO2 released right after the pyruvate dehydrogenase complex reaction e) Total no. of acetyl CoA mols. entering the Citric Acid Cycle f) Total no. of net cytosolic ATP mols. produced right after glycolysis g) Total no. of all NADH mols. produced after complete oxidation h) Total no. of all FADH2 mols. produced after complete oxidation i) Total no. of all mitochondrial…
Calculate what the intracellular glucose concentration should be if to transport glucose in active form from the external medium (c1 = 5 mM) at 37 ºC, a energy input of + 2970 J / mol.
Imagine that in red blood cells (RBCS) the following concentrations were noted for the "adenylate pool": [ATP] = 2000 uM; [ADP] = 270 uM; and [AMP] = 30 uM. ASsume that the pH is 7 and remains constant. a) calculate the Energy change (EC) (to four decimal places for RBCS given the above values. Show work b) If the [ATP] decreases by 5%, calculate the new [ATP], [ADP], and [AMP] given that the concentrations of all three species are "connected" by the adenylate kinase reaction, which is shown below. You will need to use the quadratic equation for this one. show your work. %3| %3D ADP + ADP ATP + AMP Keq = 0.44
Rat heart muscle operating aerobically fills more than 90% of its ATP needs by oxidative phosphorylation. If each gram of tissue consumes O2 at the rate of 12.0 micromol/min, with glucose as the fuel source. (a) Calculate the rate at which the heart muscle consumes glucose and produces ATP. (b) Consider an alternate scenario – what would be the rate of consumption if the energy source was a solely triglycerides whose fatty acyl chains were each 14-C in length and saturated? (Assume the O2 consumption rate remains at 12.0 micromol/min) (c) For a steady-state concentration of ATP of 6.0 micromol/g of heart muscle tissue, calculate the time required (in seconds) to completely turn over the cellular pool of ATP if glucose us used as the sole fuel source. What does this result indicate about the need for tight regulation of ATP production? (Note: Concentrations are expressed as micromoles per gram of muscle tissue because the tissue is mostly water.)

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