Side-effects of non-steroidal anti- inflammatory drugs (NSAIDS) include all, except Peptic ulcer Reduced kidney function GIT bleeding O Seizures Ketoprofen: is a propionic acid derivative that inhibits both COX (non selectively) and * lipoxygenase True False
Q: Discuss disease states caused by the malfunctioning of glycolysis, PDH and the TCA cycle.
A: Major metabolic pathways in humans are glycolysis, citric acid cycle, oxidative phosphorylation,…
Q: Hydrocortisone is a drug with both (relatively mild) glucocorticoid AND mineralocorticoid effect.…
A: Addison's disease It is also called as adrenocortical insufficiency characterized by insufficient…
Q: Which of the following medications does not have hypoglycemic effects (does not augment insulin…
A: hypoglycemia occurs when the blood sugar (glucose) level is lower than normal values ie way less…
Q: When the production of acetyl-CoA exceeds the body’scapacity to oxidize it, acetoacetate,…
A: The primary energy source in the body is carbohydrate metabolism. When carbohydrates are present in…
Q: Name criterion, which is not indicate hypoparathyroidism: A.…
A: Hypoparathyroidism is a condition characterized by abnormally low levels of parathyroid hormone…
Q: Indicate whether each of the following statements is true or false. If false, correct the statement…
A: Glucose is the most abundant monosaccharide. It is mainly made by plants and most algae during the…
Q: Explain the Dietary Sources, RDA factors affecting absorption, function and deficiency…
A: iron is a very important mineral in our diet it is an essential component of hemoglobin, which is…
Q: List the effects of glucagon on the liver and their consequences.
A: Glucagon hormone is polypeptide hormone in nature which is produced by alpha cells of pancreatic…
Q: Calcitonin has the following biological effects, except:A. Inhibition of vitamin D activityB.…
A: Calcitonin is a peptide hormone secreted by the parafollicular cells of the thyroid gland in humans.…
Q: Excess intake of what vitamin can mask the early signs of a vitamin B12 deficiency and lead to…
A: Vitamin B12 is a water-soluble vitamin that is naturally present in some foods, added to others, and…
Q: Nancy suffers from insulin dependent diabetes Mellitus and is on insulin therapy. You administered…
A: Insulin dependent diabetes mellitus (IDDM) is known as type I diabetes. It typically occurs in…
Q: Explain why the drug cortisone (kor′ti sōn), a steroid closely related to cortisol, is prescribed to…
A: The drug cortisone is a man made version of the naturally occurring hormone cortisol. Both man made…
Q: Clinical picture of hypothyroidism includes all the following symptoms except:A. HyperdefecationB.…
A: Hypothyroidism: It is a condition in which thyroid gland of an individual is not able to produce…
Q: Alpha-glucosidase inhibitors are contraindicated in all of the following cases, except:A. Diabetic…
A: Alpha glucosidase inhibitors are generally used in the treatment of type-II diabetes. Alpha…
Q: d. Epinephrine stimulates breakdown of glycogen in muscles when there is an immediate need for…
A: d. When there is an immediate energy need, epinephrine, and glucagon trigger and stimulates the…
Q: Gluconeogenesis in the liver is activated by O increased circulating levels of glucagon O increased…
A: Gluconeogenesis is the metabolic pathway during which glucose is synthesized from non Carbohydrate…
Q: Define the following terms:a. Cori cycleb. glucagonc. glucose-alanine cycled. hypoglycemiae.…
A: Molecular biology is the field of biology which studies composition, structure, and interactions of…
Q: b. In addition to its effects on glucose homeostasis, which one of the following is an effect of…
A: A hormone is any individual from a class of flagging particles in multicellular life forms, that are…
Q: Insulin stimulates B-oxidation but inhibits fatty acid biosynthesis. O True False
A: Asked : Statement is true or false.
Q: A man with Type 2 diabetes is receiving a combination of oral drugs to maintain glycemic control. He…
A: Diabetes mellitus is the condition in which there is an excess amount of sugar in the body. It is…
Q: Glucagon affects liver cells, causing increased glycogenolysis. true or false
A: Glycogenolysis is the biochemical process by which the glycogen is broken down into…
Q: In people with diabetes mellitus Type 1, explain the reason for:(a) ketoacidosis, and (b) ketonuria.
A: The condition in which the blood has high glucose level is called diabetes or diabetic mellitus.…
Q: A deficiency in sorbitol dehydrogenase cause all of the following except: Select one: a. pathologic…
A: Enzymes are biocatalyst that speeds up the chemical reaction. They play an important role in…
Q: Mutations in glucokinase which lower the kcat for the enzyme or elevate the Km for glucose result in…
A: Introduction : Glucokinase is a protein that works with phosphorylation of glucose to…
Q: What are the two most important hormones for regulating changes in glucose and fat metabolism (e.g.…
A: Amylase is not a hormone, so out of answers for this. Epinephrine, Norepinephrine and Cortisol are…
Q: Describe how metabolism can be altered
A: Metabolism can be defined as the set of chemical reactions that occur in the body that help the body…
Q: Laboratory findings show elevation of TSH concentration and increment in T3 and T4 level. State the…
A: Thyroid stimulating hormone, additionally called thyrotropic hormone, may be a glycoprotein hormone…
Q: Describe the effects of hyperaldosteronism.
A: The zona glomerulosa cells present in the cortex of the adrenal glands produce a mineralocorticoid…
Q: Alpha cells in the pancreas secrete in response to blood sugar levels, which is defined as and…
A: Hypoglycemia occurs when your blood sugar (glucose) level is lower than normal. Glucose is your…
Q: After 16 hours of fasting, your brain cells need energy and since brain uses glucose as a major…
A: Introduction Fasting:- It is abstinence from food or drink or both for health, ritualistic,…
Q: Insulin gives a signal to inactivate hormone-sensitive lipase by dephosphorylation. TRUE/FALSE
A: Glucose refers to the sugar (carbohydrate) found in the blood that is used as the primary energy…
Q: A client with Type 1 diabetes mellitus is admitted to the hospital in a semi-conscious state with…
A: Diabetic ketoacidosis is acute complication of type 1 DM
Q: During prolonged starvation or in uncontrolled diabetes mellitus, the formation of acetyl-CoA…
A: Since you have asked multiple subparts in single question. Am answering first three subparts and for…
Q: Type I diabetes is a type of diabetes in which the body produces little to no insulin. a type of…
A: A gland is an organ that is located throughout the body and it releases certain substances that…
Q: Dietary fiber delays gastric emptying time and shortens intestinal transit time. What metabolic…
A: Shorter the gastric emptying time and longer the intestinal transit time , more is the absorption of…
Q: Discuss the 3 mechanisms of abnormal carbohydrates metabolism that result in the development of…
A: Acetone, beta-hydroxybutyrate and acetoacetate are three ketone bodies. Acetyl CoA is the precursor…
Q: What is the most dangerous adverse effect following use of biguanides?A. Lactic acidosisB.…
A: Introduction The glucose is the main source of energy and the simplest carbohydrate which is…
Q: The following clinical features of Addison’s disease are all correct, except:A. Diffuse…
A: Endocrine glands are important glands that secrete various hormones. These hormones are essential…
Q: Adverse effects of oral hypoglycemic agents. What is hepatotoxity and why is it serious.
A: Oral hypoglycaemia agent is the drug used to decrease blood glucose level. Lifestyle modification…
Q: Identify the statements that are TRUE regarding Glucagon. SELECT ALL THAT APPLY A. Glucagon…
A: Glucagon and insulin are antagonostic hormones that are secreted by alpha and beta cells of pancreas…
Q: Adverse effects of oral hypoglycemic agents
A: As per our policy, we are answering the first question only. For the rest of the questions, kindly…
Q: Which of the following side effects is not usually seen with overdose of calcitriol (vitamin D3)…
A: Hypoparathyroidism is a disorder that occurs when the body secretes low level of the parathyroid…
Q: All of the following qualities apply to nateglinide, except:A. Short half-lifeB. Minimal risk for…
A: Diabetes mellitus is also known as hyperglycemia, is an endocrine disorder of the pancreas. In this…
Q: Insulin is obligatory in the following states, except:A. Light course of type 2 diabetes mellitusB.…
A: Diabetes is a metabolic disorder that results in high blood glucose level in the body Insulin…
Q: Alcoholism is often associated with hepatomegaly (due to lipid deposits) and lactic acidosis.…
A: Fatty liver disease is a condition that occurs when the liver stores too much fat. Consumption of…
Q: cortisol is responsible for adjusting homeostasis under conditions of chronic stress shuch as…
A: Starvation is a condition in which there is a severe deficiency of energy in the body due to very…
Q: Discuss the differences in the response of a diabetic person compared to those of a nondiabetic…
A: Your body uses glucose for energy. Glucose metabolism requires insulin, a hormone produced by your…
Q: Sorbitol accumulates in diabetics leading to reduced Na+/K+-ATPase activity in the retinal cells.…
A: Diabetic retinopathy is a major problem in health issues. In the polyol pathway, the glucose is…
Step by step
Solved in 3 steps
- escribe some of the general effects of ibotenic acid/muscimol poisoning and list the two main species responsiblefor this type of poisoning. Describe the effects of coprine poisoning and relate this to alcohol consumption. Describe the effects of psilocybin poisoning. Describe the effects of poisoning with gastrointestinal irritantsWhich of the following medications, when taken prior to eating, is especially effective for correcting postprandial hyperglycemia after a high-carbohydrate meal, so that hypoglycemia post dosing is minimized? Acarbose Glyburide Glitazone Tolbutamideamlodopineisosorbide monontrate extended releasemetoprolol succinate extended releasethese are name of medications Please do not plarized no hand written thank you
- One of the indications for prescribing nateglinide is:A. Depletion of pancreatic beta-cellsB. Significant postprandial hyperglycemiaC. Tendency to develop lactic acidosisD. Resistance to sulfonylureasE. Insulin resistancePossible treatments, if any, along with their biochemical basis of inherited metabolic disease of Congential Adrenal Hyperplasia . Show the chemical structures of any drugs that are discussed as well as their mechanism of action.Aspirin can alleviate clinical because it inhibits the synthesis of certain eicosanoids. True O False
- Dexamethasone 1 Dexamethasone is a glucocorticoid administered as an anti-inflammatory agent and immunosuppressant. It is structurally similar to cortisol produced naturally by your adrenal glands. It treats a number of conditions including inflammation, arthritis, autoimmune conditions, skin and eye conditions, asthma, multiple sclerosis, blood or bone marrow disorders, different types of cancer (e.g. leukemia and lymphoma), and severe allergies. This medication is also administered to patients with severe COVID-19 symptoms to decrease mortality rates*. Given that it is a steroid, which family of macromolecules does dexamethasone belong to? *research from the University of Oxford, "Randomised Evaluation of COVID-19 Therapy" trial, recovery.net 2 Given the structures of dexamethasone (left) and cortisol (right) below, and that they both bind to the same receptor, would you expect the binding of dexamethasone to be to the active or allosteric site of the receptor? 3 Based on the…Give a brief pathophysiology of diabetic kito acidosis.Including the signs and symptoms of DKAPHARMACOLOGY IN PRACTICE SAFE DRUG ADMINISTRATION A client with diabetes mellitus and hypertension is on insulin and enalapril for the hypertension. Which of the following interactions would occur with the combined administration of both drugs? 1. Increased risk of hypersensitivity reaction 2. Increased risk of electrolyte imbalance 3. Increased risk of hypoglycemia 4. Increased risk of hypotensive effect
- Clinical picture of hypothyroidism includes all the following symptoms except:A. HyperdefecationB. DrowsinessC. Slow speechD. Weight gainE. Pernicious anaemiaAdherence to guidelines of administration of oral ketoconazole can be demonstrated by?Overdose of paracetamol causes liver damage, How? what is the mechanism behind this? Explain at your own words