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Using PEN and PAPER ONLY, illustrate a SARS-CoV-2 virion. Label the ssRNA and the 4 structural
proteins. Indicate (write) the structural protein that has significant gene mutations in the Omicron
variant and that make the virus more contagious.
Please draw it and label.
Step by step
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- Using PEN and PAPER ONLY, illustrate a SARS-CoV-2 virion. Label the ssRNA and the 4 structuralproteins. Indicate (write) the structural protein that has significant gene mutations in the Omicronvariant and that make the virus more contagious.Illustrate a SARS-CoV-2 virion. Label the ssRNA and the 4 structural proteins. Indicate (write) the structural protein that has significant gene mutations in the Omicron variant and that make the virus more contagious.Indicate whether the following sentences is either True or False and CORRECT the wrong sentences ( please answer the two questions 1 and 2) : 1. Simian Virus 40 (SV40) is an example of is a circular ssDNA belong to Polyomavirus, was first isolated from primary cell cultures derived from rhesus monkey kidneys, and activates p53. 2. SARS-COV-2 is an enveloped, icosahedral virus that is surrounded by a lipid bilayer and causes COVID-19 pandemic .
- Names: The world is in a state of pandemic crisis due to the emergence of a new pathogen – SARS CoV2. Conduct outside reading in peer-reviewed journals or national sites such as CDC and integrate this information with material from class. 1. What is the distinction between SARS-COV2 and Covid-19? 2. Compare the molecular nature and size of the SARS-COV2 and HIV genomes and the contents and structure of their virions. 3. What interaction does the HIV virus use to enter cells versus the SARS CoV-2 virus? 4. How can a monoclonal antibody (Regeneron) be used therapeutically? What patient's may benefit from it? 5. What drug designed to treat Ebola is now in clinical trials for Covid-19? How does it work? 6. Explain three different types of ELISA tests. Describe how you could use one of them to detect SARS. 7. Why would ELISA or PCR be a better diagnostic test for Covid-19? 8. What are the limitations in using ELISA and PCR for Covid-19 diagnosis? 9. You are working on a research project…Answer the following and inlcude the references SARS-CoV-2, the virus that causes CoVid-19, belongs to the Coronaviridae family. Viruses under this family have a genome made of single-stranded positive-sense RNA. Is this similar to the viral genome of HIV? If so, do you think that – in theory – they would have similar replication cycles? Do you think that ART combinations/options might help in suppressing the viral replication of SARS-CoV-2? Expound.Using PEN and PAPER ONLY, illustrate a SARS-CoV-2 genome organization showing all the genes.Label the 4 structural genes and the 2 genes that code for the PP1a and PP1b and produces 16nonstructural proteins.
- Cite 3 critical differences between the genome and replication cycles of HIV and SARS-CoV-2. Explain how HIV interactions with the immune system differ from SARS-CoV-2. Discuss the possible mechanisms by which HIV causes a long-term chronic infection whereas Ebola infection is acute and often rapidly fatal.Briefly describe the events leading to the synthesis of viral proteins. Begin with the genome; assume this is a negative single-stranded RNA virus (-SSRNA).Choose all the true statements regarding coronavirus proteins. Vaccine preventable diseases include COVID-19. For coronaviruses, it is more likely to find evolving mutations in the portion of the spike protein than the nucleocapsid protein. Mutations in the genetic code for the spike protein will produce 3D changes that are more likely to affect vaccine efficacy than changes to the nucleocapsid protein code. The nucleocapsid protein interacts with viral nucleic acid specifically whereas the spike protein interacts with the host protein non-specifically.
- What is the best option for the COVID-19 vaccine and why? State your reason with more than 500 wordsWhat is the mode of replication of the virus? (this can be presented as a diagram with narrative description) What are its differences from HIV?Discuss how recombinant DNA technology could be used to develop a diagnostic method for the novel coronavirus SARS-CoV2 (ssRNA genome) currently causing the COVID-19 pandemic.