Progeny resulting from crosses of yellow x yellow mice Yellow Non-yellow Investigators progeny progeny pi Cuénot 263 100 Castle and 800 435 Little Both 1063 535 combined
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In the early 1900s, Lucien Cuénot studied the genetic basis of yellow coat color in mice (). He carried out a number of crosses between two yellow mice and obtained what he thought was a 3 : 1 ratio of yellow to gray mice in the progeny. The following table gives Cuénot’s actual results, along with the results of a much larger series of crosses carried out by Castle and Little (W. E. Castle and C. C. Little. 1910. Science 32:868–870).
Q.Combine the results of Castle and Little and Cuénot and determine whether they are significantly different from a 3 : 1 ratio and a 2 : 1 ratio.
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