Phosphoric acid is a tri-acid. It is often associated to biological molecules (i.e. proteins, lipids) in the form of phosphate group. Its ionisation state depends on the pH of the solution and of its pKa values. Data: pka₁ = 2.1; pKa2 = 7.2 ; pka3 = 12.4 1- What are the forms present at physiological pH (7.4) ? 2- Indicate which form is the most prominent.

Chemistry: Principles and Practice
3rd Edition
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Author:Daniel L. Reger, Scott R. Goode, David W. Ball, Edward Mercer
Publisher:Daniel L. Reger, Scott R. Goode, David W. Ball, Edward Mercer
Chapter15: Solutions Of Acids And Bases
Section: Chapter Questions
Problem 15.135QE
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Phosphoric acid is a tri-acid. It is often associated to biological molecules (i.e.
proteins, lipids) in the form of phosphate group. Its ionisation state depends on the
pH of the solution and of its pKa values.
Data: pka₁ = 2.1; pKa₂ = 7.2 ; pka3 = 12.4
1- What are the forms present at physiological pH (7.4) ?
2- Indicate which form is the most prominent.
Transcribed Image Text:Phosphoric acid is a tri-acid. It is often associated to biological molecules (i.e. proteins, lipids) in the form of phosphate group. Its ionisation state depends on the pH of the solution and of its pKa values. Data: pka₁ = 2.1; pKa₂ = 7.2 ; pka3 = 12.4 1- What are the forms present at physiological pH (7.4) ? 2- Indicate which form is the most prominent.
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