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Q: Rank the labeled N atoms in the anticancer drug imatinib (trade name Gleevec) in order of increasing…

A: According to Lewis acid-base theory, the acidic and basic nature of the substance. A Lewis base can…

Q: Rank the following compounds in the order of INCREASING acidity. но но он II II IV

A: Ans) 2<4<3<1

Q: Which among the given compounds are less acidic than compound I? II and IV   II and III   III and…

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Q: please help?

A: Here we can decide by using electronegativity factor,  Oxygen have  highest electronegativity then…

Q: Rank the following compounds in order of increasing basicity in aqueous solution, east basic first…

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Q: Rank the following compounds in order of increasing basicity. NH2 NH2 CONH2

A: Basicity is the ability of a compound to donate electron pair to the other electron deficient…

Q: Rank the following in order of increasing acidity. HS. H3C° НО. A

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Q: Decide which N atom in each molecule is most basic and draw the product formed when each compound is…

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Q: Decide which N atom in each molecule is most basic and draw the product formed when each compound is…

A: In above compound nitrogen atom marked as 1 is more basic .  Because the lone pair of electron of…

Q: Answer the following questions about erlotinib and terbinafine. Erlotinib, sold under the trade name…

A: Since your question has multiple sub-parts, we will solve only first three sub-parts for you. If you…

Q: Rank the attached compounds in order of increasing acidity.

A: The ability of a compound to donate hydrogen ions is called acidity. The acidic nature or acidity is…

Q: Caftaric acid is found in grapes, wine, and raisins. Rank the labeledprotons in caftaric acid in…

A: Acidity order: Carboxylic acid> phenol>alcohol>alkene

Q: Arrange the following compounds or anions in each group in order of decreasing basicity: (a) H3C−,…

A: There is a relationship between the strength of an acid and its conjugate base. The weaker the acid…

Q: Arrange the following compounds in order of decreasing their acidity (most first) I. H20 II. C2H6…

A: The acidic strength of any compound depends on the stability of their conjugate bases. with the…

Q: What is the correct rank of the following compounds in order of decreasing acidity? LOH _NH2 он II…

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Q: Rank the following organic compounds in order of increasing basicity. A)I< III < || CH2 B) I| < III…

A: The explanation is given below-

Q: 3. Explain which compound is more acidic and circle the most acidic proton.

A: Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: Decide which N atom in each molecule is most basic, and draw the product formed when each compound…

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Q: Propranolol is an antihypertensive agent – that is, it lowers blood pressure. (a) Which proton in…

A: Propranolol is an antihypertensive agent and it lowered the blood pressure. Structure of propranolol…

Q: Draw the structure of a constitutional isomer of compound B that fits each description. a. an isomer…

A: The given compound is,

Q: Rank the following compounds from strongest acid to weakest acid:

A: pKa value for the given compounds are,

Q: b. diethylamine, with sulfuric acid diethylamine – weak base sulfuric acid – strrong acid -…

A: The reaction of sulphuric acid with diethyl amine۔

Q: Which of the N atoms are basic in ciprofloxacin? Explain A) N1      B.) N9            C.) N12

A: The basicity of a base depends on the availability of lone pairs. The higher the availability of…

Q: Rank the compounds in each group in order of increasing basicity.

A:

Q: Rank the nitrogen atoms in each compound in order of increasing basicity. Isoniazid is a drug used…

A: Since the basicity of N depends on 2 factors. 1) whether its lone pair electrons are involved in…

Q: Which compound would be the weakest acid? O CH3CHCICHCICO2H O CHCI2CH2CH2CO2H CH3CCI2CH2CO2H O…

A: minus Inductive effect  is directly proportional to acidic character

Q: Maraviroc, a drug used to treat HIV, is prepared by reductive amination of aldehyde A with amine B.…

A: Reductive amination reaction- Reaction of amine with carbonyl compounds produces imine. Imine on…

Q: Amphetamine is a powerful stimulant of the central nervous system. (a) Which proton in amphetamine…

A: Acidic hydrogen is the one that can be easily removed from the compound.  Removal of hydrogen or…

Q: Rank the following compounds in order of increasing acidity. А: В: С:

A: Applying concept of aromaticity and %s character.

Q: Rank the following compounds in order of increasing acidity

A:

Q: Rank the compounds in each group in order of increasing basicity.

A: Basicity- The ability of compound to donate lone pairs of electrons or accept protons is called…

Q: Rank the compounds in each group in order of increasing basicity. NH2 NH2 NH2 а. NHз -NH2 -NH2 O,N…

A: According to Lewis theory the compound which can donate lone pair of electrons is called base, and…

Q: Which among the given compounds are more basic than compound I? II and III   IV and V   III and IV

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Q: Which of the following would be the best base for performing the following elimination reaction? *…

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Q: Rank the labeled nitrogen atoms in each compound in order of increasing basicity. Histamine causes…

A: Increasing order of basicity of nitrogen atoms in each compound depends on the involvement of the…

Q: Which compound in each pair is the stronger acid?

A: Since the strength of acid depends on the stability of its conjugate base formed after removing…

Q: с. d. .CI HO

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Q: Following is the structure of pyridoxamine. CH2NH2 CH2OH но. H3C N. a) Which nitrogen atom of…

A: Please find your solution below : (a) Amines are Lewis base and hence act as electron donor. The…

Q: Rank the following compounds from strongest acid to weakest acid

A: pKa value for the given compounds are,

Q: СООН ОН CH3 СООН NO2 CI

A: The order of acidity is as follows: I&gt;II&gt;IV&gt;III Acidity is basically, the tendency to loose…

Q: Amphetamine is a powerful stimulant of the central nervous system. (a) Which proton in amphetamine…

A: a) Since the H which on removal by forming a -ve charge on atom gives most stable -ve charge will be…

Q: Which N atom in each compound is more basic? What product is formed when each compound is treated…

A: The availability of lone pair of electrons will indicate the basicity of N atom. In amides, the…

Q: Decide which N atom in each molecule is most basic, and draw theproduct formed when each compound is…

A: Different organic compounds have different functional groups. The reactivity of the organic…

Q: The following three derivatives of succinimide are anticonvulsants that have found use in the…

A: Acidity of compound is mainly depending upon the Ka value or the acid dissociation constant.The…

Q: Rank the following compounds in order of decreasing basicity ( N' NH NH C

A: A base is an electron pair donor and basicity is the ability of a base to accept protons. Basicity…

Q: Draw the structure of a constitutional isomer of compound B that fits each description. an isomer…

A: The given compound is,

Q: Quinapril (trade name Accupril) is a drug used to treat hypertension andcongestive heart failure.…

A: To determine the most basic site, first look for the non-halogen atoms having lone pairs i.e.…

Q: (a) NCH3 (b) NH2 -

A:

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.