Melphalan, a drug used in chemotherapy, reacts with itself in the body before binding with its target, as illustrated in the mechanism below. What is the first pattern of arrow pushing seen in this reaction? (Look at the first arrow coming from the Nitrogen with a lone pair).  a. rearrangement c. nucleophilic attack

Chemistry by OpenStax (2015-05-04)
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Chapter18: Representative Metals, Metalloids, And Nonmetals
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Problem 53E: In drawing Lewis structures, we learn that a hydrogen atom forms only one bond in a covalent...
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Melphalan, a drug used in chemotherapy, reacts with itself in the body before binding with its target, as illustrated in the mechanism below. What is the first pattern of arrow pushing seen in this reaction? (Look at the first arrow coming from the Nitrogen with a lone pair). 

a. rearrangement
c. nucleophilic attack
HO
Cod-For
HO
NH₂
melphalan
-N:-
NH₂
Transcribed Image Text:HO Cod-For HO NH₂ melphalan -N:- NH₂
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