Please provide correct answer Lipidomics has identified thousands of cellular lipids. LIPID MAPS is an online database containing over 40,000 unique lipidstructures, as well as information on the chemical and physical properties of each lipid. One important parameter when workingwith lipids is logP, where P is the octanol:water partition coefficient, an indicator of lipophilicity.Look up cholesterol, sphingosine, linoleic acid, and stearic acid in LIPID MAPS and use the reported log P values to place themin order of decreasing solubility in octanol.Most soluble in octanolstearic acidlinoleic acidcholesterolsphingosineLeast soluble in octanol Log P values are often studied by pharmacologists when developing new drugs.Select the statements that describe why knowing a drug's log P value would be informative.Log P determines a drug's binding affinity for receptors on the cell membrane.Log P determines the likelihood that a drug will be absorbed by fats and fatty tissues.Log P determines the ability of a drug to be transported through aqueous compartments of the body.Log P determines a drug's stability at higher temperatures.

Answered: Image /qna-images/answer/c4076f7f-a481-4de6-8693-76e10952c8e4.jpg

Lipidomics has identified thousands of cellular lipids. LIPID MAPS is an online database containing over 40,000 unique lipid structures, as well as information on the chemical and physical properties of each lipid. One important parameter when working with lipids is logP, where P is the octanol:water partition coefficient, an indicator of lipophilicity. Look up cholesterol, sphingosine, linoleic acid, and stearic acid in LIPID MAPS and use the reported log P values to place them in order of decreasing solubility in octanol.

Lipidomics has identified thousands of cellular lipids. LIPID MAPS is an online database containing over 40,000 unique lipid structures, as well as information on the chemical and physical properties of each lipid. One important parameter when working with lipids is logP, where P is the octanol:water partition coefficient, an indicator of lipophilicity. Look up cholesterol, sphingosine, linoleic acid, and stearic acid in LIPID MAPS and use the reported log P values to place them in order of decreasing solubility in octanol.

Chemistry: Principles and Reactions

8th Edition

ISBN:9781305079373

Author:William L. Masterton, Cecile N. Hurley

Publisher:William L. Masterton, Cecile N. Hurley

Chapter23: Organic Polymers, Natural And Synthetic

Section: Chapter Questions

Problem 46QAP: Glycolysis is the process by which glucose is metabolized to lactic acid according to the equation...

See similar textbooks

Similar questions

Oceanic uptake of carbon dioxide is thus described:CO2 (g) + H2O ⇔ H2CO3, K = [H2CO3]/PCO2 = 3 x 10-2 M atm-1 H2CO3 ⇔ HCO3- + H+, K = [HCO3-][H+]/[H2CO3] = 9 x 10-7 moles/LHCO3- ⇔ CO32 - + H+, K = [CO32 -][H+]/[HCO3-] = 7 x 10-10 moles/LCharge balance equation:[H+] = [OH-] + [HCO3-] + 2[CO32 ] If the CO2 concentration in the atmosphere is 300 ppm, what is the pH of the ocean?
2 When 50 cm' of hydrochloric acid of concentration 2.0 mol dm is added to 50 cm' of sodium hydroxide solution of concentration 2.0mol dm, the temperature increase is 13.0°C HCl(aq) + NAOH(aq) + NaCl(aq) + H,O(1) The experiment is repeated using 25 cm of the same hydrochloric acid and 50 cm' of the same sodium hydroxide solution. What is the temperature increase? O A 4.9°C I B 6.5°C I C 8.7°C D 13.0°C
One technique for studying the energetics of protein structure is to monitor the struc- ture of the protein as a function of the osmotic pressure. In these experiments the os- motic pressure of the solution is varied by using polymers of different molecular weight and concentration. In an experiment poly(ethylene glycol) (PEG) with a molecular weight of 1000.0 g mol- was used. What concentration of PEG is needed to create an aqueous solution with an osmotic pressure of 150.0 Pa at 25°C? You may assume that PEG is uncharged and that it does not dissociate or aggregate.
The melting temperature of a DNA molecule (in the sense of the temperature at which it undergoes denaturation) can be determined by calorimetric methods. The following data were obtained in 0.010 M Na3PO4(aq) for a series of DNA molecules with varying base pair composition, with f the fraction of G-C base pairs:f 0.375 0.509 0.589 0.688 0.750Tm/K 339 344 348 351 354Estimate the melting temperature of a DNA molecule containing40.0 per cent G-C base pairs.
Use E5C.1(a) to Plot the data in excel. Place two data sets on the same graph: one for temp vs. x and one for temp vs y (remember, x and y are the mole fractions and they belong on the x-axis). Don’t forget to include the boiling points of the pure substances – they are data, too. Add a trendline (polynomial, 3rd order should work) to each of the coexistence lines separately. Scale the plot appropriately and use the graph to answer the questions. Then complete E5C.1(b)
You carry out an experiment on the physical properties of 3 organic compounds and observe the following data: Substance Solubility in Water medium Compound A low Compound B high Compound C You know that the 3 organic compounds are an alkene, ketone and alcohol of equal hydrocarbon length. Match the compounds above to their specific organic compound type based upon their solubility. And give a structural reason for the solubility observations that are observed. Substance Identity Reason Compound A Compound B Compound C
3. A bacteria is able to grow on hexadecane as a substrate: C16H34 + 16.28 O2 + 1.42 NH3 →1.65 C4.4HBO₂N8 + a CO₂ + 13.11 H₂O (a) What is the respiratory quotient (mol/mol)? (b) What is the cell formula for this microorganism? (c) Assuming 100% conversion, calculate the yield of cells from hexadecane (Yx/s) and from oxygen (YX/0₂).
(d) A sample contains a mixture of ammonium carbonate (NH4)2CO3, sodium carbonate Na2CO3, and sodium chloride NaCl. Thermogravimetric analysis indicates that a 0.0965-g portion of this sample loses 0.0574 g over a temperature range of 50-75 oC and then loses another 0.0124 g at 800 oC.(i) What causes the weight loss at 50-75 oC? (ii) What species will remain after being heated to 800 oC? (iii) What is the composition of the original sample? Given: Atomic masses: H = 1.008; C = 12.011; N = 14.007; Na = 22.99; O = 15.999;Cl = 35.45.
Calculate the equilibrium constant of the reaction in which glutamine is formed -O2CCH (NH3 +) CH2CH2CONH2 (hereinafter G) from glutamic acid -O2CCH (NH3 +) CH2CH2COOH (G ') in cells, under the action of the synthetase enzyme glutamine. This reaction is used to carry ammonia from the cells to the kidneys, where it is re-released and excreted. Use the value of the standard free reaction enthalpy G '(aq) + NH3 (aq) → G (aq) equal to +15.7 kJ / mol at 37 ° C. The reaction is driven by the feed-back of the ATP (aq) → reaction ADP (aq) + Pi (aq). the standard free enthalpy of which is -31 kJ / mol. What is constant equilibrium joint reaction: G '(aq) + NH3 (aq) + ATP (aq) → G (aq) + ADP (aq) + Pi (aq)?
(4.113+1 5. A monoprotic acid (HA) with K, of 8.76 x 10 has a partition coefficient of 3.9 (favoring octanol) when distributed between water and octanol, An aqueous solution (100.0 ml, pH 4.50) initially containing a 0.200 M formal concentration of HA is extracted once using 30.0 mL of octanol. a) What is the extraction efficiency? b) Calculate the formal concentration of the acid in both the water phase and the octanol phase after performing the extraction. Fwater = Foctanol = c) Would the extraction efficiency increase, decrease, or not change if the pH of the aqueous phase is adjusted to 7.00 prior to performing the extraction? no change Circle one: increase decrease Briefly explain:
(C) Write applications of bio-diesel.
Sucrose is oxidized according to the following formula. C12H22O11 + O2 → CO2 + H2O You are investigating cellular metabolism in vitro. Under your experimental conditions, you plate 12 million cells in a dish using 10 ml of cell culture media. You grow the cells in a special instrument that can measure metabolic gases. After 24 hours, you instrument has detected that 28.8 mg of oxygen have been consumed and the same mass of carbon dioxide released. Your previous tests have shown that these cells consume 75 μg/106 cells-h. (a) Determine the limiting reagent, (b) percent excess of the other reagent, percent conversion for both reactants, and (c)extent of reaction (ξ). (d) Your initial concentration of sucrose in your cell culture media is 13.0mM. Your instrumentation can only resolve sucrose concentration at 0.1 mM increments. Can you detect the change in sucrose concentration with your instrumentation?