Let's suppose that a normal chromosome carries genes labeled A through /. The centromere is located between genes B and C. As shown below, a chromosome with an inversion has a region where the order of certain genes is reversed. Note: The genes on the inverted chromosome carry recessive alleles that are designated with lowercase letters. Normal chromosome: A B Centromere C D E F G H I Chromosome with an inversion: a b Centromere c d h g fei A. If you ignore possible fertility issues, do you think this individual will otherwise be phenotypically normal or abnormal? Explain why. B. Let's suppose a single crossover during meiosis occurs between these two homologs in the region between genes F and G (and between g and f). Following the crossover, what is the order of genes (designated with upper and lower case letters) on the two resulting chromosomes. Include centromeres in your answer. Hint: Both of the resulting chromosomes will carry gene deletions and gene duplications.
Let's suppose that a normal chromosome carries genes labeled A through /. The centromere is located between genes B and C. As shown below, a chromosome with an inversion has a region where the order of certain genes is reversed. Note: The genes on the inverted chromosome carry recessive alleles that are designated with lowercase letters. Normal chromosome: A B Centromere C D E F G H I Chromosome with an inversion: a b Centromere c d h g fei A. If you ignore possible fertility issues, do you think this individual will otherwise be phenotypically normal or abnormal? Explain why. B. Let's suppose a single crossover during meiosis occurs between these two homologs in the region between genes F and G (and between g and f). Following the crossover, what is the order of genes (designated with upper and lower case letters) on the two resulting chromosomes. Include centromeres in your answer. Hint: Both of the resulting chromosomes will carry gene deletions and gene duplications.
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter11: Genome Alterations: Mutation And Epigenetics
Section: Chapter Questions
Problem 16QP: Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior...
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