Iodine-131 is commonly used for the treatment of Graves' disease, which is a disease of the thyroid gland. The

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
Chapter9: Administration By The Parenteral Route
Section: Chapter Questions
Problem 16CRQ
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Iodine-131 is commonly used for the treatment of Graves' disease, which is a disease of the thyroid gland. The number of 131I used depends on the size of the patient's thyroid gland. If the dosage for 131I is 86 microcuries per gram of the thyroid gland, and assuming all the iodine given will accumulate in the thyroid gland, then:

a. What activity dose of 131I should be given to a patient who has a thyroid gland weighing 15 grams?
b. What is the value of the decay rate constant I-131 if the half-life = 8.07 days?
c. How many grams of 131I to give?
d. How many grams of 131I are left in the patient after 1 month?

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