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Q: #3
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- 1. y-linked recessive 2. autosomal recessive 3. autosomal dominant 4. X-linked dominant 5. Pleiotrophic 6. X-linked recessive7 A heterozygote will display an autosomal recessive trait True or false3. Huntington's disease is an autosomal dominant condition in humans. The disease is often not diagnosed until adulthood, sometimes after the person has had children (and possibly passed the Huntington's allele to their children). People with Huntington's disease are usually heterozygous and not homozygous dominant. Assume that a person with Huntington's disease has a child with a person who does not have Huntington's disease. What is the probability that the child will have Huntington's disease? Support your answer with a Punnett square (on next page). 1
- What is the most likely mode of inheritance for this trait? I 1 2 1 2 3 4 6 7 OLO 2 3 4 5 6 7 8 9 10 4 5 6 II E III IV 1 □□ 1 2 3 X-linked dominant X-linked recessive Y-linked autosomal recessive autosomal dominant 516. A couple has two children; one with a widow's peak and one without. If both parents have a widow's peak what do you know to be true? 1. Both parents are heterozygous for the trait 2. Both parents are homozygous dominant for the trait 3. Both parents are homozygous recessive 4. One parent is homozygous dominant the other is homozygous recessive1. If a man, dominant homozygote for tongue rolling, is expecting a child with a woman that is heterozygotic for the trait – what is the probability for their firstborn to be a daughter being dominant homozygotic for tongue rolling? 2. A color-blind female is expecting with a color seeing male – what is the probability of a male child to see color? 3. In Sweden 1/500 are born with an autosomal recessive disorder called thalassemia. What is the carrier frequency within the population?
- 1. Mary and Joe are both healthy individuals. Joe has a mother who suffered from cystic fibrosis, an autosomal recessive disorder. Mary has been genetically tested in order to find out if she has the allele responsible for this disease and her tests came out positive. They are planning on having two children together in the near future. What is the probability that she and Joe will have either 2 boys who have the disorder, OR that they have one boy who has the disorder and one boy who does not? (in other words, what is the probability that any of these two outcomes takes place? a) 1/8 b) 1/16 c) 3/32 d) 1/64 e) 9/6426. Given that E=unattached earlobes and e=attached earlobes, which of the following best describes an individual that is homozygous recessive for this trait? 1. Attached earlobes; Ee 2. Attached earlobes; ee 3. Unattached earlobes; EE1-Polydactyly is an example of what type of allele? a-X-linked Dominant b-Dominant Lethal c-Autosomal Dominant d-Autosomal Recessive 2-Achondroplasia is an example of what type of allele? a-X-linked Dominant b-Dominant Lethal c-Autosomal Dominant d-Autosomal Recessive
- Part B 1. For the remaining characteristics, you will be looking at homozygous and heterozygous traits. Each trait will be determined to be homozygous recessive, homozygous dominant, or hetero- zygous. Letters representing the alleles will be given to you; the uppercase letter is always dominant and the lowercase letter is always recessive. If both dice rolled are even numbers, it indicates homozygous dominant alleles; if both are odd, it indicates homozygous recessive alleles; if one is odd and the other even, it indicates heterozygous alleles. 2. Eyebrows: Use the alleles "A" and "a" for this trait. Two separate brows are the dominant trait, whereas the unibrow (or one continuous brow) is recessive. 3. Eye shape: Use the alleles "R" and "r" for this trait. Round eyes are the dominant trait; almond shaped eyes are recessive. 4. Hitchhiker's thumb: Use the alleles "H" and "h" for this trait. Straight thumbs are dominant; Hitchhiker's thumbs (the curving upward of the thumb) are…1. Hemophilia is a disease inherited as a X-linked recessive trait while pattern baldness is controlled by an autosomal gene that is dominant in males and recessive in females. A hemophilic man who is also homozygous for baldness has children with a woman who is not hemophilic but a carrier and heterozygous normal-haired. Show the parental genotypes, the Genotypic ratio (GR) of the offspring and their phenotypic ratio. Separate the total number of the male offspring from female offspring. For example, if there are 8 total number of offspring, count how many are females and how many are males. So if there are 4 females, then the denominator for the genotypic ratio and phenotypic ratio for female offspring is 4. You can convert it to percentage if you want. Answer the following: a. Among the female offspring, what is the probability of having hemophilic but normal haired child? b. Among the male offspring, what is the chance of having a child with normal blood clotting but bald?re ||| E 6. Label the genotypes for this pedigree of an X-linked recessive disorder (red- green colorblindness). (a) 2 2 3 1 3 a. How do you know? b. Label the genotypes. 4 O To 2 4 5 5 6 6 7. Is the following pedigree autosomal recessive, autosomal dominant or X-linked recessive? 2 8 O T 58