how do I fix the folowing issues identified in this synthesis where the N bonds to the cyclohexane ring as indiacted: 1. Ithas a major end-game issues 2. show the synthesis of 1 - chloropropane. 3. Friedel - Crafts alkylation of primary alkylhalides suffers from rearrangement to form branched products 4. The KMnO4 reaction does not form the correctproduct, which would be oxidative cleavage of the benzylic C(sp3)-C(sp3) bond to make benzoic acid in your case.SIBAL-HCH₂ CH₁₂ CH₁₂ Cl₂AICI 3OCH2CH3H2Pd/C/-CH3JKMnO4• CH₂ CH₂ CHноон0-оно"ноNавниNH₂ LiAlHH2OCENsoczKCN

Certainly! The issues mentioned in the synthesis represent challenges or problems encountered during…

Answered: how do I fix the folowing issues…

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter16: Chemistry Of Benzene: Electrophilic Aromatic Substitution

Section16.SE: Something Extra

Problem 30MP: The carbocation electrophile in a Friede1-Crafts reaction can be generated by an alternate means...

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What is or are the expected major product(s) for the reactions below? If applicable, include stereochemistry. Br₂ a) 2-methylbut-2-ene CCI. b) c) a MeOH H₂SO4 1. BH, THF 2. H₂O₂. NaOH
10) What is the major product of the following reactions? CH3 + HCI H₂O H* ? CH3CO3 H HBr 11) Which is more highly regioselective the addition of HCl to methylenecyclohexane or to 1- methylcyclohexene? Explain. What product(s) is/are formed when the following compound react with ozone and then with dimethyl sulfide (i.e. ozonolysis)? a) b)
4. Propose a synthesis to obtain methyl propanoate from chloropropane (lesson: nucleophytic substitution reactions of acyl) A partir de: CH3 a. How can you make sure you got the expected product after purification is complete if you have no way to do spectroscopic analysis? Explain b. Considering the physical properties of the starting material and the product, what will be the biggest challenge when carrying out the reaction, separating and purifying the product?
CH3 CH3 CH3 CH;=ĊCH,CHCH;OH H2SO4, H3C H3C Referring to the above reaction: 1. Which atom does the H2SO4 first remove? 2. Identify the reaction if it's hydrogenation, hydrohalogenation, etc. 3. Propose a mechanism for the reaction, using the arrow formalism to indicate the flow of electrons.
Q1: B: How does alkylation with sulphuric acid and hydrofluoric acid work, and what are the governing process parameters? Which one is preferred for alkylation and why?
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