How could a false negative and false positive test occur in the antibody test for coronavirus? Explain your answer by discussing how the test works.
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How could a false negative and false positive test occur in the antibody test for coronavirus? Explain your answer by discussing how the test works.-A false postive can occur in a antibody test due to the test being highly specific. While the test is suppose to detetect the antibodies of Sars-Cov-2, an antibody test that has low specificity will detects other antibodies to other viruses
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- What part of the SARS-CoV-2 virus is a potential target site for a vaccine? Explain your reasoning; include in your discussion the following terms: antigen, epitope, and antibody.What component must have been present in the positive control solution (antigen, anti-HIV IgG antibodies, or secondary antibody)? Explain how you know this is true.COVID-19 is caused by infection with a novel corona virus, SARS-CoV-2. Testing someone for active infection involves examining samples taken from the nasal mucosa for fragments of the virus. Another type of testing involves examining blood for the presence of antibodies that can bind to SARS-CoV-2. Use what you've learned about the immune system. What are the suggested reasons why someone would possess antibodies to SARS-CoV-2.
- Answer the question in below and explain your answer in details with examples. Explain 3 types of vaccines that will be used against corona virus. compare whole virus(Sinovax), protein subunit(Novavax) and viral vector(AstraZeneca. explain their similarities and diffferences in detail.which would you pick, support your answer.Patient A, who is a recipient of USA-based poly X8650-CA vaccine for its autoimmune allergic rhinitis often visits the doctor twice a month to complain for “idiopathic colds”. Meanwhile Patient B, who is currently taking DOH pilot-used trial 1 mono E2128-PH vaccine for the same condition do not have to visit its doctor. Based on the principles of the antibody production, can you explain why patient A visits more often?All of the following are true about neutralizing antibodies, except: Group of answer choices Bind to the spike protein Bind to the ACE2 receptor binding domain Prevents virus from replicating in cells Have emergency approval use for use as treatment in COVID19 Allows viruses to enter cells and replicate
- 1) 286 individuals were newly diagnosed with Human Immunodeficiency Virus in 2018 in Minnesota. Of these individuals, 76% were male. HIV is an enveloped, ssRNA virus_ Baltimore classification VI. This virus targets CD4+ cells. CD4 refers to a glycoprotein which serves as a co-receptor for T-cells, located on T-helper and T-reg immune cells. a) What part of the HIV virus allows for specificity to CD4+ cells?You are interested in performing indirect immunofluorescence light microscopy to observe the localization of the catalase enzyme in the cultured HeLa cells, obtained historically from the cervical tumor of Henrietta Lacks. You were going through the lab stock and found a few primary and secondary antibodies. Which of the following secondary antibody can you use in your experiments? O All of the mentioned antibodies can be used in the experiment Goat anti-human antibody conjugated to 10 nm gold Goat-anti-human catalase conjugated to 10 nm gold O Human anti-catalase antibody conjugated to fluorescent rhodamine Goat anti-human antibody conjugated to fluorescent rhodamineThe indirect immunofluorescence ("fluorescent Ab") test shown below is performed to test for: + AA T. pallidum from Specific antibodies laboratory stock in serum of patient Antibodies bind to T. pallidum + ㅅ Fluorescent dye-labeled anti-human immune serum globulin (This will react with any immunoglobulin) Da Fluorescent spirochetes (see Figure 3.6b) None of the other four answers are correct The presence of T. pallidum bacteria in the patient's blood Whether the patient has made antibodies against other human antibodies Immunologic evidence of current or past infection with T. pallidum (i.e., Ab against T. pallidum) Growth of T. pallidum in culture from a syphilis patient
- How could you design a new SARS-CoV3 vaccine that elicits broad immunity with B cell memory to combat future mutant virus variants? Provide reasons to explain your answerYou are seeing a 4-year old girl who has a 6-week history of recurrent left knee pain and a limp. On examination, the joint is red, warm and tender but she is able to weight bear with a limp. Of the following, this girl is MOST LIKELY to test positive for:a. Anti-nuclear antibodyb. Rheumatoid factorc. Anti-double stranded DNA antibodyd. Anti-streptolysin O antibodyWhich of the following is NOT TRUE about immunological tests? Question 2 options: A Antibodies can be used to detect specific antigens B An agglutination reaction is the reaction of an antibody with a soluable antigen C An agglutination reaction is the result of a particulate antigen with a specific antibody D Based on reactions between antigen and antibody E Precipitation reactions cannot be seen with the naked eye