H-C FADH₂ FAD H₂O COO™ 1 C-H COO™™ Fumarate ADP ATP COO™ HO–CH CH₂ COO™ Malate NAD COO™ CH₂ CH₂ COO™ Succinate GTP NADH +H* Fumarase Succinate dehydrogenase Malate dehydrogenase COO H₂O Acetyl CoA C=0 CH₂ COO™ Oxaloacetate HS-CoA Succinyl CoA synthase GDP+P₁ CH₂-C-CoA COO™ CH₂ CH₂ C=0 S-CoA Succinyl COA HS-COA Citrate synthase Citric Acid Cycle a-ketoglutarate dehydrogenase CO₂ HS-CoA NADH NAD +H* COO™ CH₂ HO-C-COO™ CH₂ COO™ Citrate Isocitrate dehydrogenase COO™ CH₂ CH₂ C=0 COO a-Ketoglutarate Aconitase COO™ CH₂ H-C-COO™ HO–C-H COO™ Isocitrate NAD CO₂ NADH +H*

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Question

1. When combined with the electron transport chain, ONE turn of the citric acid cycle

 produces ___________ATP.  The citric acid cycle is shown below.

2. When all the NADH coenzymes generated from ONE turn of the citric acid cycle enter the electron transport chain, how many ATP molecules are produced? 

 

H-C
FADH,
FAD
H₂O
COO
C-H
COO™
Fumarate
ADP
ATP
COO™
HO–C-H
CH₂
COO™
7 Malate
Fumarase
Succinate
dehydrogenase
NAD+
COO
CH₂
CH₂
COO™
Succinate
GTP
NADH
+H*
Malate
dehydrogenase
COO™
C=0
CH₂
COO™
Oxaloacetate
HS-CoA
Succinyl CoA
synthase
GDP+P₁
H₂O Acetyl CoA
CH₂-C-CoA
COO™
CH₂
CH₂
C=0
S-CoA
Succinyl COA
HS-COA
Citrate
synthase
Citric Acid Cycle
a-ketoglutarate
dehydrogenase
CO₂
NADH NAD
+H*
HS-COA
COO™
CH₂
HO-C-COO™
CH₂
COO™
Citrate
Isocitrate
dehydrogenase
СОО
CH₂
C=0
СОО
a-ketoglutarate
Aconitase
COO™
CH₂
H-C-COO™
HO-C-H
COO™
Isocitrate
NAD
CO₂
NADH
+H*
Transcribed Image Text:H-C FADH, FAD H₂O COO C-H COO™ Fumarate ADP ATP COO™ HO–C-H CH₂ COO™ 7 Malate Fumarase Succinate dehydrogenase NAD+ COO CH₂ CH₂ COO™ Succinate GTP NADH +H* Malate dehydrogenase COO™ C=0 CH₂ COO™ Oxaloacetate HS-CoA Succinyl CoA synthase GDP+P₁ H₂O Acetyl CoA CH₂-C-CoA COO™ CH₂ CH₂ C=0 S-CoA Succinyl COA HS-COA Citrate synthase Citric Acid Cycle a-ketoglutarate dehydrogenase CO₂ NADH NAD +H* HS-COA COO™ CH₂ HO-C-COO™ CH₂ COO™ Citrate Isocitrate dehydrogenase СОО CH₂ C=0 СОО a-ketoglutarate Aconitase COO™ CH₂ H-C-COO™ HO-C-H COO™ Isocitrate NAD CO₂ NADH +H*
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