Genotypes of leopard frogs from a population in central Kansas were determined for a locus (M) that encodes the enzyme malate dehydrogenase. The following numbers of genotypes were observed: Calculate the genotypic and allelic frequencies for the population (round to the nearest thousandth). f(M1M1) =

Genotypes of leopard frogs from a population in central Kansas were determined for a locus (M) that encodes the enzyme malate dehydrogenase. The following numbers of genotypes were observed: Calculate the genotypic and allelic frequencies for the population (round to the nearest thousandth). f(M1M1) =

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter19: Population Genetics And Human Evolution

Section: Chapter Questions

Problem 9QP: Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic...

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Genotypes of leopard frogs from a population in central Kansas were determined for a locus (M) that encodes the enzyme malate dehydrogenase. The following numbers of genotypes were observed: Genotype Number M1M1 20 M1M2 45 M2M2 42 M1M3 4 M2M3 8 M3M3 6 Total 125 a. Calculate the genotypic and allelic frequencies for this population. b. What would the expected numbers of genotypes be if the population were in Hardy–Weinberg equilibrium?
What is the first variable that can be calculated given these data, and what is the final variable we are requesting you to calculate? "In Finland, 256 people out of 10,000 are homozygous for the CCR5 allele mutation resulting in HIV resistance. Assuming the locus is in Hardy-Weinberg equilibrium, what is the expected genotype frequency of heterozygous carriers for the CCR5 mutation?"
Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic frequencies of the MN blood group locus (see Question 2 for a description of the MN blood group) in a small human population. You find that for 1-year-old children, the genotypic frequencies are MM = 0.25, MN = 0.5, and NN = 0.25, whereas the genotypic frequencies for adults are MM = 0.3, MN = 0.4, and NN = 0.3. a. Compute the M and N allele frequencies for 1-year-olds and adults. b. Are the allele frequencies in equilibrium in this population? c. Are the genotypic frequencies in equilibrium?
A study on blood types in a population found the following genotypic distribution among the people sampled: 1101 were MM, 1496 were MN and 503 were NN. i) calculate the allelic genotypic frequencies. ii) using x² test, determine whether or not this population is in Hardy-Weinberg equilibrium. Important information from the x² distribution is given in the picture attached.
The gamma globulin of human blood serum exists in two forms, Gm(a+) and Gm(a-), specified respectively by an autosomal dominant gene Gm(a+) and its recessive allele Gm(a-). Broman et al. (1963) recorded the tabulated phenotypic frequencies in three Swedish populations. Assuming the populations were at Hardy-Weinberg equilibrium, calculate the frequency of heterozygotes in each population.
Jean Manning, Charles Kerfoot, and Edward Berger studied genotypic frequencies at the glucose-6-phosphate isomerase (GPI) locus in the water flea. They collected 176 animals from a single location in Union Bay in Seattle, Washington, and determined their GPI genotypes using a technique known as electrophoresis. The data are presented below: Genotype Number s1s1 s¹ s² $²$² What is the allelic frequency of the S2 variant within this population? O a. 0.004 O b.0.023 O c.0.131 O d. 0.216 Oe. 0.869 4 38 134
What is the expected genotype frequency of the heterozygous genotype under the Hardy-Weinberg equation P = 0.7?
A total of 1000 members of a Central American population are typed for the ABO blood group. In the sample, 421 have blood type A, 168 have blood type B, 336 have blood type O, and 75 have blood type AB. Part A Use this information to determine the frequency of ABO blood group alleles in the sample. Recall that when considering genes with three alleles whose frequencies are represented by the variables p, q, and r, the sum of genotype frequencies resulting from trinomial expansion is: (p+q+r)² =p² + 2pq+q2+2pr+r²+2gr = 1
Cystic fibrosis is an autosomal recessive disease characterized by two copies of a mutated CFTR gene. If one in 100 (hypothetical scenario, not reality) people in the United States have cystic fibrosis, calculate the p and q frequency for the normal allele (p) and the mutated allele (q). Based on those calculations, what percentage of individuals would be expected to be homozygous dominant?
The following frequencies were gathered in an African population affected with sickle-cell anemia: SS, 75.5%; Ss, 23.0%; ss, 1.5% (S = normal hemoglobin allele; s = mutant hemoglobin allele). Calculate the genotypic frequencies and determine whether this data represent a population that is in HWE.
Suppose there is an autosomal locus of 2 alleles, A1 and A2, with probabilities (frequencies) p1 and p2, and the genotype probabilities (frequencies) are P(A1A1) = p1*p1, P(A1A2) = 2*p1*p2, and P(A2A2) = p2*p2, respectively. Prove the Hardy-Weinberg Law, i.e., after one generation of random mating, the genotype probabilities (frequencies) in the offspring are also P(A1A1) = p1*p1, P(A1A2) = 2*p1*p2, and P(A2A2) = p2*p2. Hint: List all possible combinations of random mating. Then list the probabilities of the resulting genotype probabilities (frequencies) in the offspring. Combine the probabilities of random mating and resulting genotype probabilities (frequencies) in the offspring.
A population of wookies is polymorphic for the fur color, which is controlled by two loci. 230 have black hair, 64 have brown hair, and 32 have yellow hair. You test suspect that the epistatic interactions between the two loci are reponsible for this ratio and wish to test that hypothesis using a X^2 test. a) What is the most likely epistasis? b) Complete the following X^2 table. For the first three columns, enter your answer as intergers with no demical points. For the last column, enter your answer to two deimal points e.g 4.36 Fur Observed Expected O-E (O-E)^2 (O-E)^2/E Black 240 Brown 64 yellow 32 total 336 X^2