Figure 2 illustrates how Pitx1 transcription is regulated in different tissues. The center image is that of a stickleback embryo. The drawings in the surrounding boxes show the Pitx1 gene region and activator proteins present in the jaw, pelvis, eye, or pituitary tissues. a. List all the tissues shown in Figure 2 that express the Pitx1 gene. b. If a fish does not produce activator 1 proteins because of a mutation in the gene that encodes those proteins, Pitx1 will be expressed in which of the following tissues? c. If a fish does not produce activator 3 proteins, Pitx1 will be expressed in which of the following tissues?
Figure 2 illustrates how Pitx1 transcription is regulated in different tissues. The center image is that of a stickleback embryo. The drawings in the surrounding boxes show the Pitx1 gene region and activator proteins present in the jaw, pelvis, eye, or pituitary tissues. a. List all the tissues shown in Figure 2 that express the Pitx1 gene. b. If a fish does not produce activator 1 proteins because of a mutation in the gene that encodes those proteins, Pitx1 will be expressed in which of the following tissues? c. If a fish does not produce activator 3 proteins, Pitx1 will be expressed in which of the following tissues?
Chapter11: The Great Communicator
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3. Figure 2 illustrates how Pitx1 transcription is regulated in different tissues. The center image is that of a stickleback embryo. The drawings in the surrounding boxes show the Pitx1 gene region and activator proteins present in the jaw, pelvis, eye, or pituitary tissues.
a. List all the tissues shown in Figure 2 that express the Pitx1 gene.
b. If a fish does not produce activator 1 proteins because of a mutation in the gene that encodes those proteins, Pitx1 will be expressed in which of the following tissues?
c. If a fish does not produce activator 3 proteins, Pitx1 will be expressed in which of the following tissues?
d. A fish inherits a mutation in the Pitx1 coding region. This is a nonsense mutation that introduces a premature stop codon, resulting in a nonfunctional protein. Where would you expect Pitx1 to be expressed in this scenario?
Transcribed Image Text:Jaw
Pelvis
Activator 1
Activator 2
Pituitary
switch
Pelvic
Pituitary
switch
Jaw
Jaw
Pelvic
switch
switch
switch
switch
Pitx1
Pitx1
Eye
Pituitary
Activator 3
Activator 4
Pituitary
Pituitary
switch
Jaw
Pelvic
Jaw
Pelvic
switch
switch
switch
switch
switch
Pitx1
Pitx1
Figure 2
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