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- Example 5 Anti-A 0 Problem: Causes: Resolution: Anti-B 2+mf A1 Cells 3+ B Cells 0B2. During a mass spectrometry experiment, the spectrum of vascular endothelial growth factor A (VEGF-A) was acquired. The absolute error of VEGF-A, having a mass of 1024.5210 Da was 0.06 Da. Calculate the relative error (ppm). (10 marks)explain the most likely steps of what might happen inside a MDA-MB-231 cell after it is exposed to UV light.
- 5 1 point What are the units used to measure the concentration of phage in a lysate? plaques/uL Oplaques/mL plaque forming units/mL plaque forming units/uL Previous1) Explain the principle of the electrical impedance cell counting. 2) State 3 Haematology analyzer and their manufacturers. 3) CV for automated instrument is +/- 1% to +/- 2% compared to manual count with CV +/- 10%. Can you explain their differences?talk about Von willebrand factor test Within two pages
- 4 Natalizumab is a therapeutic monoclonal antibody that targets the cell- adhesion molecule a4-integrin and is used as a second-line therapy for severe Crohn's disease. What might be its mechanism of action?22:23 1O 000 · 11:24 A9 OB1 r ll l 52% . +964 782 734 3923 2m541139927815107... Patient Encounter Part 3 The pretreatment workup is summarized below. Pathology: 47-year-old female with new diagnosis of infiltrating intraductal adenocarcinoma involving the left breast and regional node. Further tests on tumor samples indicated ER (8%), PR (negative), HER2 (negative), Ki-67 (72%), and grade (poorly differentiated). Intrinsic subtype (luminal B, HER2-negative). Radiology: FDG-PET/CT indicated a 5.3 x 2.5 cm mass in the left breast which appeared to extend to the epidermis of the skin; one node in the left axilla was also involved with tumor. No other evidence of distant disease was visualized. Laboratory: CBC, liver, and kidney function tests WNL, alkaline phosphatase and calcium are normal also. Stage: IB (T, N, M,) List the most important prognostic factors in this patient with newly diagnosed breast cancer. Assess the patient's level of risk for relapse. 50 SECTION 16 | ONCOLOGIC…B. The concentration profile of drug diffusion in a tumor spheroid is given by: Qr3 ди + C = r². 3D ar a. Derive an equation for u in terms of r b. Find u, when drug dissolves only to 10% from the surface of the spheroid (assume the radius of the spheroid as b; the concentration of drug at the surface as up). c. Plot the tumor spheroid concentration profile.
- Compare and contrast GPCRs with RTK. Please keep brief - 10 sentences/dot points max.What is the working principle of Lateral flowimmunochromatographic assays (LFIAs)? Supported with a figure and reference plzwhat is the frequency of the rarest variant you can detect during deep sequencing of a tumor cell if you coverage is 250X? - 0.5% - 0.4% - 25% - 4%