Epithelium–Mesenchyme transitions (MET or EMT) are crucial morphogenetic events occurring during gastrulation. Give at least 3 specific examples of embryonic structures that develop in this manner, and the regulatory mechanisms that govern this transition. How would our understanding of this regulation affect cancer prognosis and treatment?

Epithelium–Mesenchyme transitions (MET or EMT) are crucial morphogenetic events occurring during gastrulation. Give at least 3 specific examples of embryonic structures that develop in this manner, and the regulatory mechanisms that govern this transition. How would our understanding of this regulation affect cancer prognosis and treatment?

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter51: Animal Development

Section51.5: Organogenesis

Problem 3C

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What statement best describes the difference between "fate maps" and "specification"? If cells are transplanted from their normal region in an embryo to a different region in a recipient embryo, such cells will alter their fate, but not their specification. Cell fate map describes the allocation of cells to the germ layers, ectoderm, mesoderm, or endoderm, whereas specification describes the exact tissues that each cell will ultimately become. The fate map of an embryo does not change during development -- the fate map of an egg is the same as the fate map of a late blastula -- whereas the specification map of an embryo changes continually as the embryo's development proceeds. The fate map of a cell is determined by labelling that cell and following it during normal development, whereas the specification state of a cell is determined by culturing a cell in an artificial medium and observing what tissues form from it.
If cells choose to become trophoblast, they will end up in the placenta. If they choose to become ICM, they will give rise to the 3 germ layers that will make up the rest of the body of the embryo. Explain what rpocesses or mechanisms will guide them to make the right decision. Do they have a choice?
A classical experiment studying the fate determination of stem cells in the developing embryo uses the transplantation of somites from one organism to another. In such an experiment, a scientist transplanted somites 20, 21, and 22 from the right side of the neural tube from five-day-old developing quail embryos into chick embryos. The transplantation was performed in two orientations so that the order of the somites was sometimes reversed. Use the passage to answer the question. Central self-tolerance in the immune system arises when maturing T cells in the thymus undergo apoptosis when they bind to self-antigens. Based on this information, what would MOST likely occur as the chick immune system develops? A. T cells would recognize transplanted quail somites as foreign and rapidly divide. B. T cells would recognize transplanted quail somites as foreign and undergo apoptosis. C. T cells would recognize transplanted quail somites as self and rapidly divide.…
A classical experiment studying the fate determination of stem cells in the developing embryo uses the transplantation of somites from one organism to another. In such an experiment, a scientist transplanted somites 20, 21, and 22 from the right side of the neural tube from five-day-old developing quail embryos into chick embryos. The transplantation was performed in two orientations so that the order of the somites was sometimes reversed. Use the passage to answer the question. Suppose that somite stem cells commit to their cell fates by three days post fertilization. Which result would be MOST likely in the chick embryos receiving somites transplanted in the reverse order? A. The organs arising from quail somites develop in a normal order because local signaling molecules appropriately pattern the developing organs. B. The organs arising from quail somites develop in a normal order because transcriptional programs activated in the nucleus cannot be reversed.…
A classical experiment studying the fate determination of stem cells in the developing embryo uses the transplantation of somites from one organism to another. In such an experiment, a scientist transplanted somites 20, 21, and 22 from the right side of the neural tube from five-day-old developing quail embryos into chick embryos. The transplantation was performed in two orientations so that the order of the somites was sometimes reversed. Use the passage to answer the question. Observations of the developing chick embryo reveal that skeletal muscles develop from the transplanted somites even though motor neurons innervating those muscles arise from chick neural crest cells. Based on these observations, what is MOST likely true? A. Neural crest cells differentiate into somites. B. Neural crest cells fuse with developing somite cells. C. Neural crest cells develop from migrating somite cells. D. Neural crest cells send projections into developing…
A classical experiment studying the fate determination of stem cells in the developing embryo uses the transplantation of somites from one organism to another. In such an experiment, a scientist transplanted somites 20, 21, and 22 from the right side of the neural tube from five-day-old developing quail embryos into chick embryos. The transplantation was performed in two orientations so that the order of the somites was sometimes reversed. Use the passage to answer the question. As the somite cells develop into muscles, regular depolarizations in the muscles are required for the brain to properly form circuits with developing organs. Based on this observation, which prediction is MOST likely true? A. The muscles release neurotransmitters to stimulate the innervating neurons. B. The innervating neurons release neurotransmitters to stimulate the muscles. C. The muscles release hormones to stimulate the innervating neurons. D. The innervating neurons…
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Researchers investigated the step-by-step processes of cell differentiation in somites through experiments in which cells were transplanted from one location to another early after somite formation. What did these experiments show? The cells of a somite are determined as the somite matures in response to cell-to-cell signals. The cells of a somite are irreversibly determined as soon as the somite is formed, based on cell-to-cell signals. The cells of a somite are determined as the somite matures in response to internal cytoplasmic signals. The cells of a somite are irreversibly determined as soon as the somite is formed, based on internal cytoplasmic
In neurulation, what cell types are involved? What morphogens are present (and antagonists)? What transcription factors are there? What tissues/tissue types are there? What are the signaling pathways used and how do each function? What's the end goal, and what is the response in development? Draw a labeled diagram or detailed flow chart of neurulation in embryos to show this.(FYI, this is one practice question. No grading involved.)
Zygote Embryo Muscle cells Intestinal cells Liver cells Blood cells Nerve cell Cardiac cells (1) Specialization occurs, resulting in the formation of a great variety of cell types. (2) Genes are inserted into the zygote to allow for the formation of different cell types. (3) The expression of genes responsible for the different cell types is controlled by the placenta. (4) The genetic information in the zygote is divided to produce a complete set for each cell type
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cells of other germ layers such as neuronal cells from ectodermal lineage. This Mesenchymal stem cells are one of the adult stem cells with a germ spesific mesodermal differentiation capacity as well as partial specialization ability into qualification of adult stem cells 103 31200103 A. plasticity B. immortalization totipotency E. pluripotency D0103 31200103 31200103 31 31200103 D3 31200103 31200103 31200103 31200103 31200103 31200107 31200103 31200103 31200103 31200103 3120