Describe the development of internal and external sexual in individuals who inherit XX sex chromosomes and no genes from a SRY region. Be sure to mention 1) secretion of follicle-stimulating, luteinizing, anti-Müllerian hormones; 2) gonads and the hormones and gametes they produce; 3) external sexual traits that are developed
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- Discuss whether the following individuals (1) have male or female gonads, (2) are phenotypically male or female (Wolffian or Muellerian ducts. External genitalia) and (3) are sterile or fertile._____ is a form of 46,XY intersex that affects chromosomal males. It is by far the most common form of 46,XY intersex. These individuals have testes that produce testosterone, but their bodies lack working androgen receptors. When these individuals are born they often have female-typical genitalia, and they develop female secondary sex characteristics at puberty. They also tend to develop a female gender identity. A) Androgen insensitivity syndrome B) Turner's syndrome C)Congenital adrenal hyperplasia D) 5-alpha reductase deficiencyWhich of the following is true regarding the determinants of sexual development: the presence of the gene for HY antigen on the Y chromosome determines whether a testis develops from the gonadal ridge. the presence of MIS determines whether the Wolffian ducts develop. the presence of estrogen determines whether a vagina develops. the presence of DHT determines whether a prostate develops.
- Which of the following is TRUE about the mechanism of sex determination? A) The product of the SRY gene converts the bipotential gonads into testes. B) The development of an ovary is conditioned by the presence of two X chromosomes. (C) Testosterone promotes the degeneration of the Mullerian duct. D. The ovary produces a Wolffian inhibition factor that causes the Wolffian duct to degenerate. E) The "feminization" of accessory sex orgarts is promoted by the ovary.Discuss whether the following individuals (1) have male or female gonads, (2) are phenotypically male or female (Wolffian or Muellerian ducts. External genitalia) and (3) are sterile or fertile. a) XY, homozygous for a recessive mutation in the testosterone biosynthetic pathway, producing no testosterone b) XX, heterozygous for a dominant mutation in the testosterone biosynthetic pathway, which causes continuous production of testosteroneIn male fetuses, testosterone is converted into ___ Which is required for genitalia to develop into a penis and scrotum. Complications in the activity of this hormone can disrupt the development of external sex organs in male fetuses, and can produce intersex variations. A) estradiol B) dihydrotestosterone C) Müllerian inhibiting hormone D) luteinizing hormone
- The period of female fertility during each Month is short For fextilization to take place intercouce must occur each a) A few hours before ovalation up to 4-5 days after avulation b) Around 24 hours before ovulation up to around. 24 hours after ovulation C) Sometimes between 2-3 days before ovulation upto 2-3 days after ovulation d) Around 4-5 days before ovulation upto a few hours after ovulation E) Around 4-5 days before ovulation upto 4-5. after ovulation.Select the FALSE statement/s: A) The functional layer of the endometrium sloughs off when estrogen levels are at their lowest but progesterone levels at their highest. 1 OB) Every month, the 20 secondary follicles release 20 ova. OC) XX genotypic female exposed to high levels of androgen in utero will develop male-like exfernal genitalia OD) Both A and B OE) Both B and CIn vertebrate animals, spermatogenesis and oogenesis differ, in that 1.) Cytokinesis is unequal in oogenesis whereas it i equal in spermatogenesis 2.) spermatogenesis is not completed until after fertilization occurs, but oogenesis is completed by the time a girl is born 3.) Oogenesis produces four haploid cells, whereas spermatogenesis produces only one functional spermatozoon 4.) Oogensis ends at menopause. Whereas spermatogenesis is finished before birth 5.) Oogensis begins at the onset of sexual maturity whereas spermatogenesis happens in embryonic development
- With reference to sex determination in humans, discuss: i) X chromosome inactivation; and ii) Testicular feminizationa) Define Disorders of Sex Development (DSD). b) Explain why gene mutations affecting gonad development may lead to DSD conditions. c) What is sex-chromosome mosaicism? When and how may this mosaicism arise?What is the expected effect on reproduction on an individual with hormone levels shown above? Identify two physiological changes that will not occur due to the atypical hormone levels shown above. The graph above shows the estrogen and progesterone levels of an individual during a menstrual cycle of 28 days. The top light blue line indicates the progesterone levels and the bottom purple line indicates the estrogen levels. This individual is in luteal phase.This individual can be expected to have low levels of FSH and LH.