Cyclin B-cdk1 controls entry into mitosis. What is the cyclin B-cdk1 doing to cause mitosis to occur? Phosphorylating proteins involved in nuclear membrane structure. Phosphorylating proteins involved in forming the spindle fibers. Phosphorylating proteins involved in chromosome condensation. All of the above.
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- Choose all of the TRUE statements. Hint: 4 statements are true. Cytokinesis occurs the same way in both plant and animal cells. Sister chromatids are genetically identical. The term chromosome can be used to describe both chromosomes composed of one and two chromatids. Mitosis results in daughter cells that are genetically identical to the parent cell. All eukaryotic somatic cells are diploid. Cyclin dependent kinases are present but not active in cell cycle regulation without the presence of cyclin proteins. Chromosomes are always visible in the cell.The cell in image is ... in interphase S phase mitosis G1 phase and one conclusion that can be drawn is : TRAP150 co-localizes with DNA TRAP 150 is cytoplasmic a clear conclusion cannot be drawn TRAP 150 does not co localize with dnaWhich of the following is NOT correct answer about telophase of mitosis: The mitotic spindle is formed in this phase Two new nuclei form, and two sets of chromosomes Nuclear membrane and nucleoid reappear in this phase The enzyme aminoacyl TRNA synthetase charges the TRNA molecules with the correct amino acids FRNA molecules with the correct amino acids MRNA molecules with the correct amino acids
- Which of the following statements regarding cyclin B is FALSE? Group of answer choices It is a component of the mitosis or maturation promoting factor (MPF) Its production and activation is linked to extracellular stimuli It interacts and activates CDK1 protein kinase Its destruction by APC/C signals the end of mitosis All of the above are trueIn the mitotic spindle, astral microtubules function to: connect the spindle poles attach chromosomes to the spindle carry out cytokinesis anchor the spindle poles to the plasma membraneThe activity of cyclin dependent kinases is regulated by: B Their concentration inside the cell D Their concentration outside the cell C Changes in the concentration of cyclins The G1, G2 and M checkpoints The start and end of mitosis
- The centromeric connections between chromatids fail to be severed. Kinetochores from sister chromatids become attached to microtubules from the same pole. A motor protein at the kinetochore is not functional. The chromosomes fail to attach to the kinetochore microtubules. Chromosomes will not move to the metaphase plate. Chromatids will not separate during anaphase. One kinetochore will detach from the spindle. Chromosomes will not move toward centrosome during prometaphase.Which statement is likely true given the infomation in the diagram? Net1 Cdc20 APC АРС Cdc5/Polo Cdc14 -- Cdc20 APC АРС Hct1 Hct1 Lag Mad2 Cdc20 Hct1 Cdc14 APC APC Incomplete spindle Sict Sic1 В Cdk1-cyclin Anaphase inhibitors Mitotic cyclins S/G2 Metaphase Anaphase Spindle disassembly Cytokinesis DNA re-replication O Cdc5/Polo is a phosphatase. O An overactive, gain of function mutation in Mad2 would cause metaphase arrest. O A overactive, gain of function mutation in Cdc14 would cause prolonged metaphase or metaphase arrest. O The outcome of Cdh1/Hct1 activity is a rapid rise in MPF/M-CdkC activity. H-1Which of the following events does not normally occur in mitosis? Separation of sister chromatids from each other Formation of synaptonemal complexes Attachment of spindle fibers to centromeres Movement of sister chromatids to opposite poles Alignment of chromosomes along the metaphase plate
- // Which one of these does CDK1/cyclin mitotic kinase NOT do to induce mitosis? Phosphorylates Histone H1 to condense chromosomes Phosphorylates pore proteins to disassemble pores Phosphorylates transcription factors to shut off transcription Phosphorylates lamins for lamin assemblyMitosis occurs in stages. Which represents best the correct order? O Anaphase>Metaphase>Prometaphase>Prophase>Telophase>Cytokinesis O Prometaphase> Metaphase>Anaphase> Telophase>Prophase>Cytokinesis O Cytokinesis>Anaphase>Metaphase>Prometaphase>Prophase>Telophase O Metaphase>Anaphase> Telophase>Prophase>Cytokinesis> Prometaphase O Prophase >Prometaphase> Metaphase>Anaphase> Telophase>CytokinesisB. Cyclin-dependent Kinase 1. What are the proteins that determine the forward momentum of the cell cycle? 2. What essential nutrient (aside from protein) is needed so that the cycle may grow or develop? 3. What do you infer, in what conditions will the cell may advance the cell cycle? Explain briefly. CDK Activity G₁ G₁ Checkpoint The cyclin-CDK system checks for favorable environmental conditions and damaged DNA. DNA Replication Checkpoint The cyclin-CDK system checks for stalled replication machinery and damaged DNA. Time G₂ G₂ Checkpoint The cyclin-CDK system checks for unreplicated or damaged DNA. Metaphase Checkpoint The cyclin-CDK system checks that all chromo- somes are attached to spindle microtubules.