Continuation of question 1 (c) An enzyme expressed by HIV, which has become a target for its treatment, is a peptidase with two aspartate groups within its catalytic region (Figure Q1 (C)). This enzyme has been shown to hydrolyse polyproteins into the shorter mature protein components of an infectious HIV virion. Ph ° R OH Asp-25 Substrate Water O-H Figure Q1(c) Catalytic Region Asp-25 (5 marks)

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter31: Immunochemistry
Section: Chapter Questions
Problem 31.72P
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Continuation of question 1
(c) An enzyme expressed by HIV, which has become a target for its
treatment, is a peptidase with two aspartate groups within its catalytic
region (Figure Q1 (C)). This enzyme has been shown to hydrolyse
polyproteins into the shorter mature protein components of an infectious
HIV virion.
Ph
°
R
OH
Asp-25
Substrate
Water
O-H
Figure Q1(c)
Catalytic Region
Asp-25
(5 marks)
Transcribed Image Text:Continuation of question 1 (c) An enzyme expressed by HIV, which has become a target for its treatment, is a peptidase with two aspartate groups within its catalytic region (Figure Q1 (C)). This enzyme has been shown to hydrolyse polyproteins into the shorter mature protein components of an infectious HIV virion. Ph ° R OH Asp-25 Substrate Water O-H Figure Q1(c) Catalytic Region Asp-25 (5 marks)
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