Complexation reaction: true or false EDTA is slowly excreted via urine because it is not metabolized by the human body. Tetracycline can be administered with antacids to increase absorption in the gastrointestinal tract. Complexation can lead to poor solubility. EDTA should only be administered by mouth. Tetracycline’s aqueous solubility decreases when complexed with calcium ions. Proteins are not capable of complexing with other drug molecules. Cyclodextrin enhances absorption and bioavailability.
Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
Complexation reaction: true or false
- EDTA is slowly excreted via urine because it is not
metabolized by the human body.
- Tetracycline can be administered with antacids to increase absorption in the gastrointestinal tract.
- Complexation can lead to poor solubility.
- EDTA should only be administered by mouth.
- Tetracycline’s aqueous solubility decreases when complexed with calcium ions.
- Proteins are not capable of complexing with other drug molecules.
- Cyclodextrin enhances absorption and bioavailability.
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