PDFtrascCoenzyme A (abbreviated CoA, HS-CoA, or CoA-SH) is one of themajor coenzymes that play a central role in metabolic pathways. Animportant role of coenzyme A is to prepare molecules containingacyl group (R-CO-) for reactions with enzymes by forming athioester bond with them as shown in the following box:PDFTebb tilPDFAlkyl groupOR-C-Acyl groupThiol groupOOH+ HS-CoA +ATPCoenzyme AAcyl COAsynthetaseO||CH₂-CH₂-CH₂-C-OH + HS-CoA + ATPODeduce the missing product for the following reaction involvingcoenzyme A.→R-C-S-CoA+AMP+PPCH₂-CH₂-CH₂-C-S-CH₂8O Thioester bondSCH₂-CH₂-CH₂-C-0-CoAAcyl CoAAcyl CoAsynthetase? + AMP + PP₁O SearchPDPDRunizrecorpPClabPDFaccinper wAGle

This question is based on enzyme catalyze reaction.

Coenzyme A (abbreviated CoA, HS-CoA, or CoA-SH) is one of the major coenzymes that play a central role in metabolic pathways. An important role of coenzyme A is to prepare molecules containing acyl group (R-CO-) for reactions with enzymes by forming a thioester bond with them as shown in the following box: Alkyl group O Thiol group R-C-OH+ HS-CoA Acyl group Coenzyme A Acyl CoA synthetase +ATP-R-C-S-CoA+AMP+PP Acyl CoA Thioester bond Deduce the missing product for the following reaction involving coenzyme A. CH₂-CH₂-CH₂-C-OH + HS-CoA + ATP Acyl COA synthetase ? +AMP+ PP₁

Coenzyme A (abbreviated CoA, HS-CoA, or CoA-SH) is one of the major coenzymes that play a central role in metabolic pathways. An important role of coenzyme A is to prepare molecules containing acyl group (R-CO-) for reactions with enzymes by forming a thioester bond with them as shown in the following box: Alkyl group O Thiol group R-C-OH+ HS-CoA Acyl group Coenzyme A Acyl CoA synthetase +ATP-R-C-S-CoA+AMP+PP Acyl CoA Thioester bond Deduce the missing product for the following reaction involving coenzyme A. CH₂-CH₂-CH₂-C-OH + HS-CoA + ATP Acyl COA synthetase ? +AMP+ PP₁

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter21: Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions

Section21.SE: Something Extra

Problem 41MP

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