CASE ANALYSIS A 30-year-old male rushed to ER presenting an undocumented intermittent fever, headache + dizziness for the last 2 days, with signs of dehydration and epistaxis. Initial assessment revealed oxygen saturation of 86% [95-100%]. Laboratory workup shows positive for Dengue IgM/IgG, and a platelet count of 15.0 mm3 (150,000 - 450,000 mm3). Consequently, the physician ordered a blood transfusion for the patient and managed the patient’s hydration status. 1.) Dehydration due to plasma leakage is brought by which of the following mechanisms? A.) Increase in fibrinogen B.) Alteration of blood vessel integrity C.) Decrease in albumin D.) Increase in hydrostatic pressure

CASE ANALYSIS A 30-year-old male rushed to ER presenting an undocumented intermittent fever, headache + dizziness for the last 2 days, with signs of dehydration and epistaxis. Initial assessment revealed oxygen saturation of 86% [95-100%]. Laboratory workup shows positive for Dengue IgM/IgG, and a platelet count of 15.0 mm3 (150,000 - 450,000 mm3). Consequently, the physician ordered a blood transfusion for the patient and managed the patient’s hydration status. 1.) Dehydration due to plasma leakage is brought by which of the following mechanisms? A.) Increase in fibrinogen B.) Alteration of blood vessel integrity C.) Decrease in albumin D.) Increase in hydrostatic pressure

Basic Clinical Laboratory Techniques 6E

6th Edition

ISBN:9781133893943

Author:ESTRIDGE

Publisher:ESTRIDGE

Chapter3: Basic Hemostasis

Section3.2: Disorders Of Hemostasis

Problem 14RQ

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I. A Case StudyA 30-year-old man was transported to the emergency room with an unexplained fever, headache, and dizziness for the past two days, as well as indicators of dehydration and epistaxis. An initial examination revealed an oxygen saturation of 86%. (95-100 percent ). A positive Dengue IgM/IgG test and a platelet count of 15.0 mm3 are found in the laboratory (150, 000-450, 000 mm3). As a result, the physician gave the patient a blood transfusion and monitored his hydration level. 1. What blood component is most likely to be impacted and exhausted based on the indications and symptoms (headache + dizziness)? 2. What plasma component is most likely to be altered (elevated) physiologically in the setting of dehydration in the patient's case? 3. In the patient's instance, which blood component was most likely decreased when he had epistaxis? 4. In the patient's situation, what type of WBC is elevated? What is the morphology and granularity of the nucleus?
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A 13-year-old girl with chronic myelogenous leukemia presented with respiratory distress 30 days after hematopoietic cell transplantation. There was an onset of breathlessness after 5-day history of hemoptysis and fever. Respiratory system showed bronchial breath sounds in right supraclavicular areas. Laboratory investigation showed mild elevation of AST/ ALT levels. Other blood parameters were normal. Initial work- up for fever, including malaria, dengue, scrub typhus, and leptospirosis tests, were negative. Hepatitis B surface antigen and HIV were also negative. Sputum samples for acid-fast bacilli were reported as negative. On the sixth day of admission, the patient’s sputum culture was reported positive for specific fungi. The green granulated colony of the cultured specimen revealed microscopically the presence of septate hyphae and small conidia. Questions: What is this patient’s most likely diagnosis? What are this patient’s most striking clinical and laboratory findings?…
A 13-year-old girl with chronic myelogenous leukemia presented with respiratory distress 30 days after hematopoietic cell transplantation. There was an onset of breathlessness after 5-day history of hemoptysis and fever. Respiratory system showed bronchial breath sounds in right supraclavicular areas. Laboratory investigation showed mild elevation of AST/ ALT levels. Other blood parameters were normal. Initial work- up for fever, including malaria, dengue, scrub typhus, and leptospirosis tests, were negative. Hepatitis B surface antigen and HIV were also negative. Sputum samples for acid-fast bacilli were reported as negative. On the sixth day of admission, the patient’s sputum culture was reported positive for specific fungi. The green granulated colony of the cultured specimen revealed microscopically the presence of septate hyphae and small conidia. Questions: What is this patient’s most likely diagnosis? What are this patient’s most striking clinical and laboratory findings?…
A 13-year-old girl with chronic myelogenous leukemia presented with respiratory distress 30 days after hematopoietic cell transplantation. There was an onset of breathlessness after 5-day history of hemoptysis and fever. Respiratory system showed bronchial breath sounds in right supraclavicular areas. Laboratory investigation showed mild elevation of AST/ ALT levels. Other blood parameters were normal. Initial work- up for fever, including malaria, dengue, scrub typhus, and leptospirosis tests, were negative. Hepatitis B surface antigen and HIV were also negative. Sputum samples for acid-fast bacilli were reported as negative. On the sixth day of admission, the patient’s sputum culture was reported positive for specific fungi. The green granulated colony of the cultured specimen revealed microscopically the presence of septate hyphae and small conidia. Questions: What are the clinical manifestations of the disease caused by the organism responsible for the patient’s infection?…